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Analisis Antibodi Ireguler pada Reaksi Inkompatibel Darah Transfusi Irna Diyana Kartika; Hilma Yuniar Thamrin; Rachmawati Muhiddin; Mansyur Arif; Ibrahim Abdul Samad
UMI Medical Journal Vol 5 No 2 (2020): UMI Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/umj.v5i2.93

Abstract

Latar belakang: Terjadi kasus inkompatibilitas karena pemberian darah yang inkompatibel dapat disebabkan oleh dua hal, yang pertama akibat ketidakcocokan golongan darah saat melakukan transfusi sehingga terjadi reaksi hemolisis intravaskular akut dan juga dapat disebabkan oleh reaksi imunitas antara antigen dan antibodi karena adanya golongan darah lain atau antibodi ireguler. Penelitian ini bertujuan untuk menganalisis antibodi ireguler pada hasil inkompatibilitas darah transfusi uji silang serasi darah transfusi. Metode: Penelitian ini merupakan penelitian observasional dengan menggunakan metode cross sectional. Sampel penelitian sebanyak 70 sampel inkompatibel uji silang serasi yang ditemukan di Unit Bank Darah RSUP Dr. Wahidin Sudirohusodo Makassar dan Unit Donor Darah PMI Makassar. Dilakukan pemeriksaan golongan darah dan uji silang serasi jika sampel yang telah di lakukan uji silang serasi dan hasilnya terjadi reaksi inkompatibel golongan darah maka sampel tersebut diambil kemudian di lanjutkan ke Direct antiglobulin test. Sampel yang Direct antiglobulin test positif dilanjutkan dengan pemeriksaan monospesifik yaitu tes IgG dan C3d. Analisis data menggunakan Metode analitik, yaitu dengan uji Chi Square untuk menilai variabel yang berhubungan dengan antibodi ireguler. Hasil: Penelitian menunjukkan bahwa, dari 70 sampel yang mengalami reaksi inkompatibilitas ternyata hanya 7 sampel yang positif memiliki antibodi ireguler, di antaranya Anti E 3 (4,29%), anti CDEd 1 (1,42%), dari ketujuh sampel yang positif terdapat 2 (2,86%) sampel yang positif semua pada sebelas sel panel tersebut dan terdapat 1 (1,42%) sampel yang positif pada sel panel kecil (sel 1 dan sel 2) untuk skrining antibodi. Kesimpulan: Kejadian inkompatibel golongan darah sebagian besar bukan karena adanya antibodi ireguler, hanya sekitar 10% inkompatibel akibat antibodi ireguler terjadi maka skrining antibodi ireguler belum menjadi urgensi di setiap Unit pelayanan Transfusi darah maupun di unit Bank darah Rumah sakit.
ZAT BESI DI PENDONOR TERATUR DAN YANG TIDAK TERATUR (Iron in Regular and NonRegular Donors) Irna Diyana Kartika; Lince Wijoyo; Syahraswati Syahraswati; Rachmawati Muhiddin; Darwati Muhadi; Mansyur Arif
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 21, No 3 (2015)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v21i3.1277

Abstract

Blood donation is a process of taking blood from someone, either voluntarily or as a replacement donor blood banked for later usein blood transfusions. Regular donors are donors who regularly donate blood between 3−4 times a year. Nonregular donors are thosewho do not routinely donate blood in a year. Each donor donating one bag of blood, suffered a loss of approximately 200 mg of iron.The purpose of this study was to know the differences in the levels of iron profiles in regular and nonregular donors. The study wasconducted cross sectional on 65 samples of blood from the UPTD Transfusi Darah South Sulawesi Provincial Health Office, consisting of34 regular donors and 31 nonregular donors. Serum iron and TIBC levels were examined using ABX Pentra 400 with colorimetric andimmunoturbidimetry method. Ferritin level was examined using Elecsys with ECLIA principle. The data were then analyzed by unpairedT test. In this study, the regular donors showed an average serum iron level of 87.09 μg/dL, TIBC level 255.41 μg/dL and ferritin level121.27 μg/dL. The nonregular donors, showed an average serum iron level of 83.26 μg/dL, TIBC level was 261.80 μg/dL and ferritinlevel was 158.62 μg/dL. The results showed no significant differences between the levels of iron profiles in regular and nonregulardonors. Based on this study, it can be concluded that regular and nonregular blood donation did not affect the levels of iron profiles. Itis recommended to conduct a further cohort research to know the levels of iron profiles in blood donors by comparing before and afterdonating blood.
Testing The Antimicrobial Effectiveness of Manila Sauce Leaves (Manilkara Zapota L) against Bacteria Escherichia Coli: In Vitro Study Azizah, Namirah Nurjiranah; Kartika, Irna Diyana; Hasbi, Berry Erida; Muchtar, Amrizal; Arsal, Andi St. Fahirah
Journal La Lifesci Vol. 5 No. 2 (2024): Journal La Lifesci
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallalifesci.v5i2.1173

Abstract

Diarrhea remains a significant public health concern globally, particularly affecting children under five years old. Traditional herbal remedies, including Manila Sapodilla (Manilkara zapota L) leaves, have been utilized in Indonesia for treating diarrhea due to their perceived efficacy and safety. This in vitro study aimed to assess the antimicrobial effectiveness of Manila Sapodilla leaf extract against Escherichia coli bacteria, a common cause of diarrhea. True experimental design was employed, utilizing various concentrations (25%, 50%, 75%, and 100%) of Manila Sapodilla leaf extract. The extract was obtained through maceration using ethanol followed by dilution with distilled water. Antimicrobial activity was evaluated using the Kirby-Bauer diffusion method, measuring inhibition zones formed around Escherichia coli colonies. Results demonstrated that Manila Sapodilla leaf extract exhibited inhibitory effects against Escherichia coli at all tested concentrations, albeit with varying degrees of effectiveness. The inhibition zones ranged from 5.37 mm to 8.53 mm, indicating resistance. Positive control using Ciprofloxacin displayed a significantly larger inhibition zone (21.75 mm), indicating sensitivity. These findings suggest the potential of Manila Sapodilla leaf extract as an alternative treatment for Escherichia coli infections. However, further research, including phytochemical analysis and exploration of different extraction methods and concentrations, is warranted to elucidate its therapeutic potential fully. This study contributes to the ongoing search for alternative herbal-based antibiotics to combat bacterial infections effectively.
Pencegahan Risiko Kesehatan Penggunaan Pupuk Anorganik Pada Petani di Desa Borisallo, Kec. Parangloe, Kab. Gowa Ulfah Sulaiman; Irna Diyana Kartika; Nasruddin Syam; Wardiah Hamzah
Indonesia Bergerak : Jurnal Hasil Kegiatan Pengabdian Masyarakat Vol. 2 No. 1 (2024): Januari : Indonesia Bergerak: Jurnal Hasil Kegiatan Pengabdian Masyarakat
Publisher : Asosiasi Riset Ilmu Teknik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/inber.v2i1.157

Abstract

Increased food production requires fertilizers and pesticides. Fertilizers are used to increase soil fertility and pesticides are used to eradicate pests in food crops and plantations. Problems of farmers in Pucak Village, Kec. Tompobulu as a partner does not know the level of exposure to pesticides, does not know the impact of pesticides on health problems and does not have Personal Protective Equipment (PPE) when spraying. The solutions are: (1) Counseling on prevention and the impact of the use of fertilizers and pesticides on the incidence of dermatitis, (2) Provision of PPE in the form of masks and gloves in fertilizing and spraying pesticides. The results of community service are (1) Counseling on prevention and the impact of using fertilizers and pesticides on the incidence of dermatitis, which is carried out by conducting home visits. Farmers experienced an average increase in knowledge of safe and healthy fertilizing and pesticide spraying management, (2) Provision of PPE, especially hats, masks and gloves to farmers. Abstract: Increasing food production requires fertilizer and pesticides. Fertilizer is used to increase soil fertility. Fertilizer has a negative impact in the form of disease and poisoning on farmers in Borisallo Village, Kec. Parangloe, Kab. Gowa as a partner does not yet know how to prevent exposure to organic fertilizers on health, there is no provision of micronutrient supplementation (Calcium, Magnesium, Zinc, Boron and Vitamin D) as an increase in body immunity and detoxification of fertilizer exposure poisoning and there is no availability of Personal Protective Equipment in managing fertilizers in the form of masks and gloves for farmers. The solutions are: (1) Counseling on preventing fertilizer exposure to farmers, (2) Providing micronutrient supplementation (Calcium, Magnesium, Zinc, Boron and Vitamin D) to increase body immunity and detoxify fertilizer poisons, (3) Providing Personal Protective Equipment (PPE) in the form of masks and gloves when carrying out inorganic fertilization on farmers. The results of community service are (1) Counseling on prevention and the impact of using organic fertilizer on health, which is carried out by conducting home visits. Farmers experienced an average increase in knowledge of safe and healthy management of fertilization and pesticide spraying, (2) providing micronutrients and explaining sources of other food ingredients containing micronutrients in their environment, (3) Providing PPE, especially hats, masks and gloves to farmers
NARRATIVE REVIEW : KARAKTERISTIK PENDERITA SINDROM PASCA COVID-19 (LONG COVID-19) Haring, Andi Muh. Batara Sakti; Wiriansya, Edward Pandu; Nurmadilla, Nesyana; Kartika, Irna Diyana; Hamzah, Pratiwi Nasir
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 3 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i3.37083

Abstract

Coronavirus disease 19 (Covid-19) saat ini menjadi masalah serius dunia dan jumlah kasusnya terus meningkat setiap harinya. Tanda dan gejala umum infeksi Covid-19 termasuk gejala gangguan pernapasan akut seperti demam, batuk, dan sesak napas. Beberapa gejala bertahan atau kambuh selama bermingguminggu atau bahkan berbulan-bulan setelah pemulihan awal. Kajian gejala Covid-19 oleh King's College London menemukan bahwa 4 juta orang yang sudah memiliki gejala Covid-19 dan hasil PCR positif lebih rentan terkena infeksi di usia lanjut, disusul fase akut, terutama yang disertai suara serak, Indek massa tubuh yang lebih, sesak napas dan jenis kelamin perempuan sering terjadi masa gejala berkepanjangan. Secara umum penelitian ini bertujuan untuk mengetahui  karakteristik penderita sindrom pasca covid-19 (long covid-19). Sedangkan secara khusus, penelitian ini bertujuan untuk untuk mengetahui  karakteristik penderita sindrom pasca covid-19 (long covid-19) berdasarkan manifestasi klinis, usia, dan jenis kelamin.  Penelitian ini menggunakan Literature Review dengan pendekatan Narrative Review. Jenis penelitian ini dipilih karena peneliti ingin mencari tahu mengenai karakteristik penderita sindrom pasca covid19 (long covid-19).  Data yang digunakan dalam literatur ini merupakan data sekunder. Data diperoleh dengan cara menelaah artikel dan jurnal ilmiah berupa penelitian terkait karakteristik penderita sindrom pasca Covid-19. Berdasakan penelitian ini disimpulkan bahwa COVID-19 dapat menyebabkan gejala persisten yang dikenal sebagai Long-Covid, yang dapat berdampak pada fungsi fisik, kognitif, dan kualitas hidup pasien.
GAMBARAN HASIL LEUKOSIT DAN NEUTROFIL PADA PASIEN APENDISITIS AKUT DI RUMAH SAKIT IBNU SINA MAKASSAR 2021-2023 Rusfandi, Alfath Aldhana; Kartika, Irna Diyana; Hasbi, Berry Erida; Purnamasari, Reeny; HB, Irmayanti
Jurnal Kesehatan Tambusai Vol. 5 No. 4 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i4.35175

Abstract

Apendisitis akut adalah keadaan darurat perut yang paling umum ditemui. Diagnosis apendisitis akut ditegakkan berdasarkan penilaian klinis dan pemeriksaan penunjang, khususnya hitung leukosit dan neutrofil. Penelitian ini untuk mengetahui profil leukosit dan neutrofil pada pasien apendisitis akut di RS Ibnu Sina Makassar. Penelitian ini menggunakan desain deskriptif kuantitatif. Pasien dengan radang usus buntu akut yang terdaftar di RS Ibnu Sina Makassar dari tahun 2021 hingga 2023 diikutsertakan. Pasien apendisitis akut berjumlah 98 orang, mayoritas berusia 17-25 tahun (38,8%), berjenis kelamin laki-laki (55,1%), dan memiliki pekerjaan sedang (69,4%). Hasil laboratorium menunjukkan leukositosis pada 79,6% kasus, dengan pergeseran ke kiri pada 53,1%. Perawatan yang paling umum adalah operasi terbuka (91,8%). Ciri-ciri penderita apendisitis akut didominasi pada kelompok umur 17-25 tahun, berjenis kelamin laki-laki, dengan leukositosis, jumlah neutrofil bergeser ke kiri, dan ditangani dengan pembedahan terbuka.
Edukasi Pencegahan dan Detoksifikasi Pajanan Pestisida pada Petani Melalui Suplementasi Mikronutrien di Desa Borisallo, Kec. Parangloe, Kab. Gowa Nasruddin Syam; Arni Isnaini Arfah; Wardiah Hamzah; Irna Diyana Kartika
Jurnal Pengabdian Bidang Kesehatan Vol. 2 No. 4 (2024): Jurnal Pengabdian Bidang Kesehatan
Publisher : PPNI UNIMMAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jpbidkes.v2i4.140

Abstract

Increasing food production requires pesticides to eradicate pests and leafhoppers that interfere with the growth of food crops and plantations. Pesticides have a negative impact in the form of disease and poisoning on farmers. Farmers are a work that is mostly carried out by the community in Borisallo Village, Parangloe District, Gowa Regency and is a partner in this service. The problems faced by partners are the lack of preventive counseling caused by pesticide exposure to farmers, the lack of micronutrient supplementation to increase body immunity and detoxification of pesticide exposure poisoning, and the unavailability of PPE in managing pesticides in the form of masks and gloves for farmers. The solutions are: (1) Counseling on the prevention of pesticide exposure to farmers, (2) Providing micronutrient supplementation to increase body immunity and detoxify pesticide toxins, (3) Providing PPE in the form of masks and gloves in spraying pesticides on farmers. The activity was carried out for 4 months with funding from the UMI Waqf Foundation. The results of the implementation of PKM (1) Counseling on the prevention of fertilizer exposure to 15 existing farmers, (2) Then continued with the provision of micronutrients and explanation of other food sources that contain micronutrients around the environment (3) Ended with the provision of PPE in the form of masks and gloves that can be used when managing and spraying pesticides. It is recommended to have thorough and periodic health checks on farmers, technical guidance related to healthy and safe fertilization methods continuously and switch to the use of organic or plant-based pesticides
Connection Amount Type Leukocytes on Student Faculty Medicine of Muslim University of Indonesia Based on Index Mass Body (IMT) M Syahwal; Sri Julyani; Andi Alamanda Irwan; Irna Diyana Kartika; Nesyana Nurmadilla
Jurnal EduHealth Vol. 16 No. 01 (2025): Jurnal EduHealt, Edition January - March, 2025
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Leukocytes play an important role in the body's immune response and can reflect a person's health condition, including the presence of infection or inflammation. In certain conditions, such as obesity, the number of types of leukocytes can change in response to inflammation that occurs in the body. The purpose of this study is to see connection amount type leukocytes with Index Mass Body (BMI) on student Faculty Medicine of Muslim University of Indonesia. Using method study quantitative with design cut cross sectional, with Technique Analysis Univariate and Multivariate. Results study show that, there was no relationship between BMI status and leukocyte count in students of the Faculty of Medicine, Muslim University of Indonesia. Researchers believe that a healthy lifestyle, higher levels of physical activity, and younger age may play a role in preventing significant inflammatory impacts in this population.
LITTERATURE REVIEW : HUBUNGAN ZIKIR DENGAN KECERDASAN EMOSIONAL PADA MAHASISWA PROGRAM PROFESI DOKTER Mohammad, Fatmawati; Mokhtar, Shulhana; Kartika, Irna Diyana
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 2 (2025): AGUSTUS 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i2.45899

Abstract

Mahasiswa program profesi dokter dihadapkan pada beban akademik yang berat, tekanan emosional tinggi, serta tantangan klinis yang kompleks. Kecerdasan emosional menjadi kompetensi penting yang mendukung keberhasilan akademik maupun profesional, mencakup kesadaran diri, empati, pengendalian emosi, serta motivasi internal. Penelitian ini bertujuan untuk mengkaji hubungan antara praktik zikir dengan penguatan kecerdasan emosional pada mahasiswa profesi dokter melalui pendekatan kualitatif berbasis studi pustaka. Data dikumpulkan dari 10 artikel ilmiah nasional dan internasional, kemudian dianalisis secara tematik. Hasil kajian menunjukkan bahwa zikir berkontribusi positif terhadap pengelolaan stres, peningkatan empati, serta pembentukan ketahanan mental (resilience) dalam menghadapi tekanan dunia medis. Praktik zikir juga terbukti selaras dengan konsep mindfulness dalam psikologi modern, menjadikannya sebagai strategi efektif dalam regulasi emosi dan pembentukan karakter spiritual mahasiswa kedokteran. Temuan ini menggarisbawahi pentingnya pendekatan spiritual dalam pendidikan kedokteran sebagai pelengkap pembentukan kompetensi klinis.
PERSEPSI MAHASISWA KEDOKTERAN TERHADAP PERILAKU PROFESIONALISME (HONOR AND INTEGRITY) Afdhaliyah, Nur; Mokhtar, Shulhana; Kartika, Irna Diyana
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 2 (2025): AGUSTUS 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i2.46126

Abstract

Profesionalisme merupakan kompetensi inti dalam pendidikan kedokteran. Nilai honor dan integritas menjadi aspek penting dalam membentuk karakter dokter yang profesional. Namun, kurangnya keberanian melaporkan pelanggaran serta ketidakpercayaan terhadap sistem penanganan etika menunjukkan perlunya evaluasi terhadap pemahaman dan penerapan nilai-nilai ini di kalangan mahasiswa. Penelitian ini bertujuan untuk mengetahui persepsi dan refleksi diri mahasiswa profesi dokter terhadap perilaku profesionalisme, khususnya aspek honor dan integritas, di lingkungan pembelajaran klinis. Penelitian ini menggunakan pendekatan deskriptif kuantitatif dengan menyebarkan kuesioner kepada 100 mahasiswa profesi dokter di Fakultas Kedokteran Universitas Muslim Indonesia. Data dianalisis secara deskriptif menggunakan skala Likert dengan interpretasi skor berdasarkan kategori persepsi dan refleksi diri terhadap profesionalisme. Hasil penelitian menunjukkan bahwa persepsi mahasiswa terhadap nilai honor dan integritas berada dalam kategori sangat positif dengan skor rata-rata 4,38. Refleksi diri mahasiswa juga tergolong sangat positif dengan rata-rata skor 4,53, yang mengindikasikan bahwa nilai-nilai profesionalisme telah dipahami dan diinternalisasi dengan baik. Meskipun demikian, ditemukan skor yang relatif rendah pada aspek keberanian melaporkan pelanggaran profesionalisme. Dengan demikian, dapat disimpulkan bahwa mahasiswa memiliki persepsi dan refleksi diri yang sangat positif terhadap profesionalisme, khususnya terkait honor dan integritas. Meski demikian, institusi pendidikan perlu memperkuat budaya pelaporan dan sistem pendukung etika agar nilai-nilai ini dapat diterapkan secara lebih konsisten dalam praktik klinis.