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All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Innovative: Journal Of Social Science Research
Wiriansya , Edward Pandu
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Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Other

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Efikasi Herba Timi (Thymus Vulgaris L.) Sebagai Antibiotik Terhadap Klebsiella Pneumoniae Nasrun, Muhammad Fikri; Wiriansya , Edward Pandu; Musa, Inna Mutmainnah; Kanang, Indah Lestari Daeng; Muchtar, Amrizal
Innovative: Journal Of Social Science Research Vol. 3 No. 6 (2023): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v3i6.8338

Abstract

Thymus vulgaris dianggap sebagai antiseptik, antimikroba, disenfektan dan obat-obatan bersifat tonik. Thymus vulgaris L. dapat digunakan sebagai bahan makanan dan bahan pengobatan karena komposisinya dengan turunan monoterpen termasuk p-cymene, thymol dan carvacrol. T. vulgaris L. memiliki sifat hepatoprotektif serta memiliki efektivitas sebagai agen ekspektoran, agen anti-jerawat, dan menjadi obat fungisida serta antivirus. Tujuan dari penelitian ini adalah untuk menilai kemampuan Thymus vulgaris L. sebagai antiobiotik terhadap Klebsiella pneumoniae dengan mengambil serbuk dari daun tanaman ini. Penelitian yang digunakan adalah penelitian experimental post test dengan menggunakan metode disc diffusion (metode Kirby Bauer) untuk melihat efektivitas dari ekstrak Herba timi (Thymus vulgaris) pada pertumbuhan bakteri Klebsiella pneumoniae. Hasil penelitian menunjukkan bahwa ekstrak daun Herba timi (Thymus vulgaris L.) tidak memiliki aktivitas sebagai antibakteri sehingga tidak dilakukan pengukuran zona hambat pertumbuhan bakteri dan mengkategorikan daya hambat bakteri Klebsiella pneumoniae, walaupun terdapat senyawa kimia aktif dalam daun Herba timi (Thymus vulgaris L.) yaitu alkaloid, saponin, flavonoid, terpenoid, steroid dan tanin.
Relationship between Serum Vitamin D Levels and Asthma Control in Adult Patients Sabaruddin, Haeriah; Djamaluddin, Fauzan; Ilyas, Muh.; Iskandar, Harun; Lihawa, Nurjannah; Nurisyah, Siti; Wiriansya , Edward Pandu
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 31 No. 1 (2024)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v31i1.2376

Abstract

Asthma is a heterogeneous disease characterized by respiratory symptoms that vary both over time and in intensity, along with limited expiratory airflow. This heterogeneity is related to the patient's genetic and environmental phenotype. Vitamin D levels can affect the severity of asthma and the success of asthma treatment. Vitamin D can also influence the effectiveness of glucocorticoid therapy as an anti-inflammatory. This study aimed to determine the relationship between serum vitamin D levels and asthma control, severity, obstruction, and exacerbation levels. This research was a descriptive cross-sectional study on asthma patients at Wahidin Sudirohusodo Hospital and its network for the period October–December 2023. Each research subject had a venous blood sample taken and then checked vitamin D levels at the Hasanuddin University Teaching Hospital Research Laboratory. This research involved 72 research subjects. Most of the research subjects were female (61.1%), aged <45 years (52.8%), worked as housewives (29.2%), had overweight BMI (33.3%), and had a history of atopy (59.7%). The degree of airway obstruction in the study subjects was mostly mild (66.7%) and the degree of severity was intermittent, persistent, and the degree of exacerbation in the same sample (33.3%). The results of the study showed a relationship between vitamin D levels and nutritional status, history of atopy, degree of asthma control using the ACT questionnaire, degree of stable asthma, and exacerbations where p<0.05. Also, it is found that a weakly positive connection (R: 0.2–0.4) between vitamin D levels and ACT, FEV1, FEV/FVC. There is a relationship between vitamin D levels and nutritional status, history of atopy, degree of asthma control using the ACT questionnaire, degree of stable asthma, and exacerbations. There was a relationship between vitamin D levels and the degree of obstruction assessed by spirometry in this study.
Co-Authors Amrizal Muchtar djamaluddin, fauzan Ilyas, Muh. Iskandar, Harun Kanang, Indah Lestari Daeng Lihawa, Nurjannah Musa, Inna Mutmainnah Nasrun, Muhammad Fikri Sabaruddin, Haeriah Siti Nurisyah