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LITERATURE REVIEW: EFEKTIVITAS MADU DALAM MENGHAMBAT PERTUMBUHAN BAKTERI STAPHYLOCOCCUS AUREUS Widias Puji; Arif Yusuf Wicaksana; Dhiah Novalina
Journal of Mandalika Literature Vol. 3 No. 1 (2022)
Publisher : Institut Penelitian dan Pengembangan Mandalika (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (106.367 KB) | DOI: 10.36312/jml.v3i1.989

Abstract

Penyakit kulit di Indonesia saat ini masih sangat marak terjadi. Hal yang paling umum terjadi hingga saat ini adalah bisul. Penyebab paling umum terjadinya bisul ialah akibat infeksi dari bakteri Staphylococcus aureus. Staphylococcus aureus merupakan flora normal yang dapat menjadi patogen apabila terjadi trauma ataupun abrasi pada permukaan mukosa. Studi di Amerika Serikat dan Eropa menunjukkan bahwa bakteri Staphylococcus aureus merupakan bakteri tersering yeng menyebabkan infeksi dengan prevalensi sebesar 18-30%, dan di Asia memiliki angka kejadian yang hampir sama. Penelitian ini bertujuan untuk menganalisis pengaruh penggunaan madu sebagai antibakteri alami dalam menghambat pertumbuhan bakteri Staphylococcus aureus. Metode yang digunakan dalam penelitian ini yaitu dengan metode literature review. Hasil menunjukkan bahwa berdasarkan diameter zona hambat, madu konsentrasi 100% lebih efektif dalam menghambat pertumbuhan bakteri Staphylococcus aureus tetapi tidak memiliki nilai rata-rata yang signifikan jika dibandingkan dengan konsentrasi lain. Madu jenis Algeria lebih besar zona penghambatannya terhadap Staphylococcus aureus, sehingga dapat dikatakan efektif dan juga memiliki nilai rata-rata yang signifikan jika dibandingkan dengan madu jenis lain.
Analysis of The Presence of Pathogen Bacteria in Rectal Swab of Food Handler at The Yogyakarta Health and Calibration Laboratory: Analisis Keberadaan Bakteri Patogen pada Rectal Swab Penjamah Makanan di Balai Laboratorium Kesehatan dan Kalibrasi Yogyakarta Ratna Kusumaningtyas; Dhiah Novalina; Irfani, Farida Noor
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 7 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i2.1760

Abstract

Food handlers are workers who are responsible for handling food from preparation to serving. In accordance with the Regulation of the Minister of Health of the Republic of Indonesia Number 1096/MENKES/PER/VI/2011, food handlers must be checked periodically every six months by carrying out anal swabs to find out whether the food handler is free. of pathogenic bacteria and act as carriers or not. This study aims to find out whether food handlers who work at Food Management Places (TPM) in Yogyakarta act as careers or not through identifying pathogenic bacteria in rectal swab samples. The type of research used was descriptive qualitative with a cross-sectional approach by taking data at BLKK Yogyakarta from January to December 2023. The sample in this study amounted to 86 data using a purposive sampling technique based on inclusion and exclusion criteria. Data were analyzed for frequency distribution and Chi-Square and Odds Ratio statistical tests were carried out. The results of the study showed that the examination was dominated by the TPM type, namely catering class B (hospital) as many as 4 (40,0%) applicants, the early adult age group (18-40 years) as many as 73 (84,9%) and gender men were 44 (51,2%) food handlers. The results of the rectal swab examination showed positive Escherichia coli bacteria (carrier) in 33 (38,4%) food handlers and there was a significant relationship between the results of the examination for pathogenic bacteria and TPM sanitation (p-value 0,023), but there was no significant relationship between results of examination of pathogenic bacteria with age (p-value 0,531) and gender (p-value 0,695).
LITERATURE REVIEW: ANALISIS PENGARUH LIFE STYLE (PEROKOK DAN NON PEROKOK) TERHADAP POSITIFITAS HASIL PEMERIKSAAN MIKROSKOPIS BAKTERI TAHAN ASAM (BTA) Fetiara Dewi; Wahid Syamsul Hadi; Sri Martuti; Dhiah Novalina; Tri Dyah Astuti
Journal Transformation of Mandalika, e-ISSN: 2745-5882, p-ISSN: 2962-2956 Vol. 2 No. 12 (2021): Desember
Publisher : Institut Penelitian dan Pengembangan Mandalika Indonesia (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jtm.v2i12.972

Abstract

Tuberculosis (TB) is a disease with potentially infectious cough symptoms caused by the bacterium Mycobacterium tuberculosis. Half of the deaths caused by TB occur in men due to smoking habits and 3.2 times smokers can be at risk of developing pulmonary tuberculosis. Early diagnosis of tuberculosis cases can be done through microscopic analysis of sputum with Ziehl-Neelsen staining in order to prevent tuberculosis cases from increasing and reducing mortality due to tuberculosis. The objectives of this study are to determine the level of positivity of the results of microscopic examination of acid-fast bacteria (AFB) in smokers and non-smokers, to determine the effect of cigarettes on the results of microscopic examination of acid-fast bacteria (AFB), and to determine the risk factors that influence the positivity of the results of acid-fast bacteria (AFB) in smokers and non-smokers. This study employed literature review method with the PICO method on two databases, namely PubMed and Google Scholar. The level of positivity of AFB microscopic examination results in smokers found AFB results +3, +1, and +2 while in non-smokers found AFB results +1 and +3. The risk factors affecting the level of AFB positivity in smokers and non-smokers included more found in male than female, productive age, and smoking history. In smokers, the level of positive of the microscopic inspection of AFB revealed the most AFB +3 result, whereas non-smokers revealed the most AFB +1 results. Male, productive age (15-64 years), and smoking history are all risk factors for AFB positive in smokers and non-smokers (type of bidi cigarettes, consumption of 10-20 cigarettes per day, and the presence of exposure to cigarette smoke).
Analisis Hasil Uji Sensitivitas Bakteri pada Ulkus Penderita Diabetes Melitus Tipe 2 di Salah Satu Rumah Sakit Yogyakarta Fadhilah Zalfa Cahyaningrum; Dhiah Novalina; Monika Putri Solikah
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 4 No. 3 (2025): Juli 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v4i3.6153

Abstract

Diabetic ulcers are a condition that occurs in individuals suffering from diabetes mellitus due to damage to the nerves and peripheral arteries, leading to wound infections and damage to the skin tissue. The focus of this research is to determine the prevalence by gender, the types of bacteria that infect diabetic ulcers, and the patterns of antibiotic sensitivity at a hospital in Yogyakarta in 2024. This research employs a descriptive analytic design using a cross-sectional approach. The sampling technique uses total sampling, selecting all members of the population who meet inclusion and exclusion criteria. The data for this study were obtained from medical records during the period from January 1st to December 31st, 2024, with a total sample size of 86 diabetic ulcer patients. Of these patients, 53 are male and 33 are female who suffer from Type 2 Diabetes Mellitus with complications of diabetic ulcers. In addition, this research found 26 types of bacteria, where gram-negative bacteria are more dominant with 51 samples, while gram-positive bacteria amount to 35 samples. The most dominant type of gram-negative bacteria detected is Escherichia coli, while the most commonly identified gram-positive bacteria is Staphylococcus aureus. The antibiotics that are sensitive to gram-negative bacteria are meropenem, cefepime, and chloramphenicol. Meanwhile, the effective antibiotics against gram-positive bacteria are linezolid, gentamicin, and ciprofloxacin.
GAMBARAN HASIL PEMERIKSAAN URINALISIS PADA PASIEN INFEKSI SALURAN KEMIH DI RSA UGM YOGYAKARTA Alifia Zulfi Lailliah; Widaninggar Rahma Putri; Dhiah Novalina
Indonesian Journal of Health Research Innovation Vol. 2 No. 3 (2025): Indonesian Journal of Health Research Innovation
Publisher : Yayasan Menawan Cerdas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64094/17zkzh09

Abstract

Infeksi saluran kemih (ISK) disebabkan oleh mikroorganisme di dalam saluran kemih. Departemen Kesehatan Republik Indonesia (DEPKES RI) tahun 2020 mengatakan sekitar 90 sampai 100 kasus ISK per 10.000 penduduk. ISK sering terjadi pada perempuan sebanyak 75 pasien dan terjadi pada usia 19-59 tahun dalam kategori dewasa. Penelitian ini merupakan penelitian deskriptif kuantitatif dengan pendekatan retrospektif, yang bertujuan untuk memberikan gambaran tentang kasus ISK. Penelitian ini dilakukan di RSA UGM Yogyakarta, dengan  sampel berupa data sekunder pasien ISK, populasi pasien ISK dari bulan Januari-Desember 2024, dengan cara consecutive sampling dan sampel sebanyak 100 sampel pasien ISK. Variabel independen: hasil urinalisis (nitrit, leukosit esterase, leukosit, eritrosit, epitel, bakteri), dan kultur urin. Variabel dependen: karakteristik pasien ISK. Hasil leukosit esterase menunjukkan 87 pasien (87%) dengan hasil positif, sel leukosit menunjukkan 89 pasien (89%) dengan hasil abnormal dan sel epitel 87 pasien (87%) abnormal. Bakteri penyebab utama yaitu E.coli sebanyak 6 pasien (25%) dari 24 pasien (24%) yang melakukan pemeriksaan kultur urin. Uji Chi- Squre menunjukkan terdapat hubungan yang signifikan antara jenis kelamin dengan hasil sel eritrosit ((p=0,010; OR=0,298, epitel p= 0,004; OR= 4,005, dan kultur urin p= 0,001; OR= 4,846)). Serta uji Chi- Square usia dengan sel eritrosit (p= 0,003; OR= 7,619). ISK lebih umum terjadi pada perempuan usia produktif dan E.coli merupakan salah satu bakteri penyebab utama ISK. Hasil pemeriksaan leukosit dan epitel yang abnormal juga menunjukkan adanya infeksi atau peradangan pada sebagian besar pasien.