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All Journal Damianus Journal of Medicine Jurnal Medika Farmaka Pharmaceutical Science Journal
Sahara, Khalipatun
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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ANALISIS EFEKTIVITAS BIAYA OBAT ANTIHIPERTENSI DOSIS TUNGGAL PADA PASIEN HIPERTENSI TANPA PENYAKIT PENYERTA: SYSTEMATIC LITERATURE REVIEW Fahriati, Andriyani Rahmah; Fadilah, Adam Rizki; Rahmawati, Adelia; Denisa, Dila; Chasanah, Eneng Uswatun; Sahara, Khalipatun; Nurhakiki, Nurhakiki; Agustian, Rizki Zaidan; Fauziah, Shifa
PHRASE (Pharmaceutical Science) Journal Vol 4, No 2 (2024): Pharmaceutical Science Journal Vol 4 No 2
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v4i2.902

Abstract

Hypertension is a disease that occurs in various countries, especially Indonesia, where financing and health care are increasingly expensive. Based on data from the World Health Organization (WHO) in 2019, there were around 1,13 billionhypertension sufferers worldwide. Hypertension is a condition where a person experiences an increase in blood pressure above normal limits which can cause disease and even death. Pharmacoeconomic research is considered a suitable solution for policy makers in determining cost-effective clinical alternative treatments. The increasing costs of chronic diseases make access and quality of health services increasingly expensive, so solutions are needed to reduce health financing problems. The method used is cost effectiveness analysis (CEA). This systematic literature review aims to analyze single antihypertensive drugs in hypertensive patients without comorbidities using various related literature. Data were collected prospectively that met the inclusion and exclusion criteria. CEA analysis is calculated by looking at the ACER (Average Cost Effectiveness Ratio) value. From the overall results of the literature review, the most cost-effective antihypertensive drug is amlodipine, with the highest ACER range of 955.66 and the lowest 7,611. So it can be concluded that the most cost-effective antihypertensive therapy is amlodipine.
Artikel Review: Analisis Kadar Klorin pada Pembalut dengan Metode Volumetri Sahara, Khalipatun; Nurohmah, Alivia; Maelaningsih, Firdha Senja; Cahyani, Lufitha Evelyne
Jurnal Medika Farmaka Vol 1 No 3 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i3.16

Abstract

Introduction: Sanitary napkins are a hygiene product that women very commonly use during menstruation. The safety and quality of sanitary napkins are essential to prevent adverse impacts on health. One crucial aspect that needs to be considered is the level of chemical pollution, such as chlorine, which has the potential to endanger health. The volumetric method is one of the most commonly used methods to measure the chlorine content in various products. In this article, the volumetric method for analyzing chlorine content in sanitary napkins consists of three methods: iodometric titration, iodometric titration, and argentometric titration. This article aims to summarize a literature review that discusses various studies regarding the analysis of chlorine levels in sanitary napkins using the volumetric method. Method: The method used in the article review is a literature review by taking journal articles containing analysis of chlorine levels in sanitary napkins using the volumetric method. Results: A review of various studies showed variations in chlorine levels in the sanitary napkin samples tested. Conclusion: Chlorine levels in sanitary napkins can be analyzed using the volumetric method, with the chlorine results that can be analyzed being in the range of 0.0022% w/v-0.0022% w/v.
Hubungan antara kualitas tidur dan depresi pada remaja: studi cross sectional Indonesian Family Life Survey 5 Suswanti, Ika; Yulia; Rahesi, Inggri Dwi; Nurmiwiyati; Sahara, Khalipatun
Bahasa Indonesia Vol 24 No 2 (2025): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v24i2.6539

Abstract

Pendahuluan: Kesehatan mental saat ini menjadi isu yang menarik untuk diteliti khususnya di kalangan remaja. Aspek biologis dan psikososial seringkali menjadi faktor penyebab depresi pada remaja. Studi ini bertujuan untuk mengetahui hubungan kualitas tidur dan aktivitas fisik terhadap kejadian depresi pada remaja berdasarkan data sekunder Indonesian Family Life Survey (IFLS) 5.   Metode: Penelitian dengan design studi potong lintang menggunakan data sekunder IFLS-5 pada periode pengumpulan data tahun 2014 sampai 2015 yang melibatkan 3.580 remaja usia 14-19 tahun. Penilaian depresi menggunakan instrument Center for Epidemiological Studies Depression Scale (CESD-10) dengan kategori depresi apabila ditemukan skor lebih dari 10 poin. Variabel lain yang diukur meliputi karakteristik demografi (usia, tempat tinggal, jenis kelamin, tingkat pendidikan), aktivitas fisik, kualitas tidur dan indeks masa tubuh. Untuk melihat hubungan antara faktor risiko dengan kejadian depresi dilakukan analisis secara bivariat menggunakan Chi Square dan multivariat menggunakan regresi logistik. Hasil: Mayoritas subjek penelitian adalah perempuan, tempat tinggal di urban, dan pendidikan SMA. Kejadian depresi pada remaja ditemukan sebesar 30,2%. Secara independen jenis kelamin perempuan, aktivitas fisik berat, serta kualitas tidur yang buruk (p<0,001) berkaitan dengan kejadian depresi pada remaja. Analisis multivariat menujukkan faktor kualitas tidur yang buruk meningkatkan kecenderungan 2,728 kali lebih tinggi untuk mengalami depresi. Sementara aktivitas fisik rendah meningkatkan 1,655 kali untuk terjadinya depresi pada remaja.   Simpulan: Angka kejadian depresi pada remaja mencapai 30,2%, memperbaiki pola hidup termasuk kualitas tidur dan aktivitas fisik menjadi faktor penting untuk mengurangi kecenderungan kejadian depresi pada remaja. Pentingnya intervensi berbasis pola tidur sehat dan peningkatan aktivitas fisik dalam upaya pencegahan depresi pada remaja.
Co-Authors Adelia Rahmawati Agustian, Rizki Zaidan Andriyani Rahmah Fahriati Cahyani, Lufitha Evelyne Chasanah, Eneng Uswatun Denisa, Dila Fadilah, Adam Rizki Fauziah, Shifa Firdha Senja Maelaningsih Ika Suswanti Inggri Dwi Rahesi Nurhakiki, Nurhakiki Nurmiwiyati Nurohmah, Alivia yulia