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Analysis Potential of Dadih as a Treatment for Diabetes Mellitus Based on Histopathological Images of the Pancreas in Mice (Mus musculus) L., Marlin Brigita; Armal, Hadits Lissentiya; Amien, A. Zakaria
Journal Of Health Science (Jurnal Ilmu Kesehatan) Vol 8 No 1 (2023): JOURNAL OF HEALTH SCIENCE (JURNAL ILMU KESEHATAN) (IN PRESS)
Publisher : Fakultas Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24929/jik.v8i1.2452

Abstract

The pathogenesis of Diabetes Mellitus is complex with one of the basic factors causing the disease is oxidative stress. Foods containing probiotics are reported to suppress oxidative stress. Probiotics containing L.acidophillus and L.casei are known to reduce oxidative stress and are antidiabetic. This happens because casei can reduce oxidative stress and suppress CD4 cells effectively, accompanied by a reduction of pro-inflammatory molecules so that it has an antioxidant effect but can also modulate the immune system. To see the role of dadih in this study, the research will be conducted using mice which are divided into three groups, namely the negative control group, the positive control group and the treatment group randomly. Blood sampling aims tomeasure blood glucose levels of mice using a glucometer. Histological observation of the mice's pancreatic organs was carried out to determine theantidiabetic effect of curd. The results of the One-Way ANOVA test showed that there was a significant difference in each treatment group (p=0.000). Giving curd can improve the pancreas of mice with diabetes mellitus seen from the histopathological picture that has pyknosis. The pathogenesis of Diabetes Mellitus is complex with one of the basic factors causing the disease is oxidative stress. Foods containing probiotics are reported
PENYULUHAN KESEHATAN MASYARAKAT MELALUI PEMERIKSAAN LABORATORIUM SEDERHANA SEBAGAI UPAYA PEMANTAUAN KESEHATAN MANDIRI Sugiarti, Mimi; Hartanty, Hartanty; Dinutanayo, Wimba Widagdho; Purnomo, Agus; Nurminha, Nurminha; Chaniago, Yusrizal; Amien, A. Zakaria; Djayasinga, Rodhiansyah
Jurnal Pengabdian Masyarakat Kesehatan Indonesia Vol. 3 No. 2 (2024): Jurnal Pengabdian Masyarakat Kesehatan Indonesia
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jpmki.v3i2.1622

Abstract

The number of cases of non-communicable diseases in Indonesia continues to increase every year. This incident can be caused by the lack of awareness of individuals in the community to carry out routine health checks so that early detection of non-communicable diseases (NCDs) based on health services becomes less effective.  Prevention of NCDs risk factors and community-based prevention is one solution that can be done to reduce the risk of mortality rate due to NCDs. The purpose of this activity is to conduct health checks in the form of screening blood glucose, uric acid, and hemoglobin levels for the community in the LKSA environment of Sholawatul Fallah Orphanage, Bandar Lampung. The implementation time is Friday, August 26, 2022, at LKSA Sholawatul Fallah Orphanage, Bandar Lampung. This activity was attended by 43 residents who checked blood glucose, uric acid, and hemoglobin levels. The results obtained that as many as 43% had high blood glucose levels, 28% had high uric acid levels, and 10% with hemoglobin results below normal. The results of the examination are recommended for further examination to the Puskesmas for the Community with high blood glucose and uric acid levels.