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All Journal JOURNAL OF HEALTH SCIENCE (JURNAL ILMU KESEHATAN) Jurnal Kesehatan Jurnal Pengabdian Masyarakat Kesehatan Indonesia
Amien, A. Zakaria
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Dentistry Education Health Professions Medicine & Pharmacology Nursing Public Health

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Analysis Potential of Dadih as a Treatment for Diabetes Mellitus Based on Histopathological Images of the Pancreas in Mice (Mus musculus) L., Marlin Brigita; Armal, Hadits Lissentiya; Amien, A. Zakaria
Journal Of Health Science (Jurnal Ilmu Kesehatan) Vol 8 No 1 (2023): JOURNAL OF HEALTH SCIENCE (JURNAL ILMU KESEHATAN) (IN PRESS)
Publisher : Fakultas Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24929/jik.v8i1.2452

Abstract

The pathogenesis of Diabetes Mellitus is complex with one of the basic factors causing the disease is oxidative stress. Foods containing probiotics are reported to suppress oxidative stress. Probiotics containing L.acidophillus and L.casei are known to reduce oxidative stress and are antidiabetic. This happens because casei can reduce oxidative stress and suppress CD4 cells effectively, accompanied by a reduction of pro-inflammatory molecules so that it has an antioxidant effect but can also modulate the immune system. To see the role of dadih in this study, the research will be conducted using mice which are divided into three groups, namely the negative control group, the positive control group and the treatment group randomly. Blood sampling aims tomeasure blood glucose levels of mice using a glucometer. Histological observation of the mice's pancreatic organs was carried out to determine theantidiabetic effect of curd. The results of the One-Way ANOVA test showed that there was a significant difference in each treatment group (p=0.000). Giving curd can improve the pancreas of mice with diabetes mellitus seen from the histopathological picture that has pyknosis. The pathogenesis of Diabetes Mellitus is complex with one of the basic factors causing the disease is oxidative stress. Foods containing probiotics are reported
PENYULUHAN KESEHATAN MASYARAKAT MELALUI PEMERIKSAAN LABORATORIUM SEDERHANA SEBAGAI UPAYA PEMANTAUAN KESEHATAN MANDIRI Sugiarti, Mimi; Hartanty, Hartanty; Dinutanayo, Wimba Widagdho; Purnomo, Agus; Nurminha, Nurminha; Chaniago, Yusrizal; Amien, A. Zakaria; Djayasinga, Rodhiansyah
Jurnal Pengabdian Masyarakat Kesehatan Indonesia Vol. 3 No. 2 (2024): Jurnal Pengabdian Masyarakat Kesehatan Indonesia
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jpmki.v3i2.1622

Abstract

The number of cases of non-communicable diseases in Indonesia continues to increase every year. This incident can be caused by the lack of awareness of individuals in the community to carry out routine health checks so that early detection of non-communicable diseases (NCDs) based on health services becomes less effective.  Prevention of NCDs risk factors and community-based prevention is one solution that can be done to reduce the risk of mortality rate due to NCDs. The purpose of this activity is to conduct health checks in the form of screening blood glucose, uric acid, and hemoglobin levels for the community in the LKSA environment of Sholawatul Fallah Orphanage, Bandar Lampung. The implementation time is Friday, August 26, 2022, at LKSA Sholawatul Fallah Orphanage, Bandar Lampung. This activity was attended by 43 residents who checked blood glucose, uric acid, and hemoglobin levels. The results obtained that as many as 43% had high blood glucose levels, 28% had high uric acid levels, and 10% with hemoglobin results below normal. The results of the examination are recommended for further examination to the Puskesmas for the Community with high blood glucose and uric acid levels.
Analysis of the Relationship between Neutrophil-Lymphocyte Ratio (NLR) Values and Body Mass Index in Tuberculosis Patients Nurfiyana, Wahyu; Amien, A. Zakaria
Jurnal Kesehatan Vol 17 No 1 (2026): Jurnal Kesehatan (In Progress)
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v17i1.5529

Abstract

Tuberculosis (TB) is a communicable infectious disease that remains a major public health problem, particularly in Indonesia. Low nutritional status can impair immune function and worsen the clinical course of TB. Body Mass Index (BMI) is commonly used to measure nutritional status. In contrast, the neutrophil–lymphocyte ratio (NLR) is a simple inflammatory biomarker reflecting the balance between innate and adaptive immune responses. This study aimed to analyze the relationship between NLR and BMI among TB patients undergoing treatment. This cross-sectional study involved 32 tuberculosis patients receiving treatment at Puskesmas Sukabumi, Bandar Lampung. NLR values were obtained from blood tests using a hematology analyzer and calculated as the neutrophil count divided by the lymphocyte count. BMI was determined from body weight and height measurements. Statistical analysis included Spearman's correlation test to examine the relationship between NLR and BMI, and a One-Way ANOVA to assess differences in NLR across BMI classifications. The results showed that the mean BMI was 20.4±3.0 kg/m², and the median NLR was 2.7. A significant negative correlation was found between BMI and NLR (r = -0.379; p = 0.03), indicating that lower BMI was associated with higher NLR. Significant differences in NLR were also observed among BMI categories (p = 0.003), with underweight subjects demonstrating the highest NLR values. These findings suggest a relationship between nutritional status and systemic inflammatory responses in TB patients. BMI and NLR may serve as simple indicators for assessing inflammatory status and monitoring treatment progress in tuberculosis patients. 
Co-Authors Agus Purnomo Armal, Hadits Lissentiya Chaniago, Yusrizal Dinutanayo, Wimba Widagdho Hartanty, Hartanty L., Marlin Brigita Nurfiyana, Wahyu NURMINHA, NURMINHA Rodhiansyah Djayasinga Sugiarti, Mimi