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All Journal Macca: Science-Edu Journal Hayyan Journal Mammiri: Jurnal Pengabdian Masyarakat
Nur, Andi Bulqiah
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Education Engineering Languange, Linguistic, Communication & Media Medicine & Pharmacology Social Sciences Other

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Journal : Hayyan Journal

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Literature Review on Chemical Compounds from Natural Ingredients that Function as Anti-Hypertension Nur, Andi Bulqiah
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.2479

Abstract

Hypertension is one of the most common health problems worldwide and is a major risk factor for cardiovascular diseases such as coronary heart disease and stroke. Many synthetic drugs are available to manage hypertension, but they often have significant side effects. Research on chemical compounds from natural materials that have antihypertensive activity is very important. This literature review aims to evaluate various chemical compounds that are derived from natural materials and have potential as antihypertensive agents. Some of the plants that have been identified as having active chemical compounds include Hibiscus sabdariffa which contains anthocyanins, Allium sativum (garlic) which contains allicin, and Andrographis paniculata which contains andrographin. Recent studies have shown that these compounds are effective in lowering blood pressure through various mechanisms such as vasodilation, diuresis, and inhibition of angiotensin-converting enzyme (ACE). This study highlights the importance of using natural ingredients as a safer and more effective alternative to synthetic drugs for the management of hypertension. However, more research is needed to develop more effective drug formulations and to test their effectiveness clinically in human populations.
Co-Authors Afni, Nur' Faathir Almur Faathir Almur Hastuti Agussalim Hastuti Agussalim Nur Afni Sitti Faika Sri Agustini