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Hubungan Dukungan Sosial Dengan Citra Diri Pada Pasien Ca Mamae Post Mastektomi Di Murni Teguh Memorial Hospital Syafitri, Indah; Sagala, Lam Murni
Indonesian Trust Nursing Journal Vol 2 No 3 (2024): Indonesian Trust Nursing Journal
Publisher : Universitas Murni Teguh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37104/itnj.v2i3.278

Abstract

Mastectomy is one of the recommended surgical procedures for breast cancer patients. As a result of this action the patient will experience a disturbance in self-image. Social support is believed to be able to influence the occurrence of an increase in one's body image, because with the involvement or acceptance of the closest people it can help in the progress of one's re-integrity so that individuals can accept the physical changes that occur in themselves. The objective of this study is to identify the relationship between social support with self-image in patients with ca mamae post mastectomy at Murni Teguh Memorial Hospital. This study was conducted on 30 respondents using a descriptive correlative methodology with a cross-sectional approach and using simple random sampling technique. The instruments used social support and self-image questionnaire on post-mastectomy patients which have been tested for validity and reliability. Statistical test using Spearman correlation test. The results of this study indicate that there is a relationship between social support and self-image in post-mastectomy breast cancer patients at Murni Teguh Memorial Hospital Medan. Statistical test using Spearman correlation test showed p value <0.005 (p value = 0.002). It is concluded that there is a relationship between social support and self-image in post-mastectomy mammary patients at Murni Teguh Memorial Hospital Medan in 2022
Potential and toxicity effects of fish omega-3 fatty acid as a chemopreventive agent in colorectal cancer: A scoping review Syafitri, Indah; Rahmawati, Riana; Miladiyah, Isnatin
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 15, No 1, (2024)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol15.Iss1.art12

Abstract

Colorectal cancer (CRC), a malignancy that affects the colon and rectum, is influenced by gene mutations, epigenetic changes, local inflammation, and lifestyle risk factors. New cases of CRC globally account for 10%, with mortality at 9.4%, while Indonesia occupies the top four incidence and mortality cases. A family history of CRC requires preventive measures, including consuming functional foods to maintain the colon microenvironment. This article aims to review the potency and toxicity effects of omega-3 fish fatty acids as a chemopreventive agent against CRC. The data sources were original articles about omega-3 fish fatty acids as CRC chemopreventive agents, published in 2012-2022 and in English or Indonesian. Databases used are Ovid, ScienceDirect, ProQuest, PubMed, Springer Link, EBSCO, and Google Scholar using Boolean search. The selection of studies followed the PRISMA-ScR method. Of the nine articles selected, fish omega-3 fatty acids had the potential as a chemopreventive agent against CRC, with several variations in daily dose ranges accompanied by a good lifestyle. Oral omega-3 fish supplementation gave benefits in the range of 96 mg–2,000 mg of eicosapentaenoic acid (EPA) and between 360 mg–1,000 mg of docosahexaenoic acid (DHA), with a daily intake varying between 0–14 grams/day. One study reported a toxic effect of fish omega-3 fatty acids, which raised the risk of post-operative infection after parenteral (intravenous) administration. There are no reported side effects across eight studies following oral preparation administration. The omega-3 fish fatty acid shows potential as a chemopreventive therapy for CRC; further studies are required to explore the parenteral administration-associated toxic effects.