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All Journal Narra J JURNAL ABDI MASYARAKAT INDONESIA (JAMIN) Jurnal Abdimas Kesehatan Terpadu
Ranggaini, Dewi
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Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Other

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Penyuluhan dan Pelatihan Peningkatan Kemampuan Menjaga Kebersihan Gigi dan Mulut serta Tatalaksana ke Dokter Gigi selama Pandemi COVID-19 Ranggaini, Dewi; Sadono, Melanie; Halim, Himawan; N Santosa, Didi
JURNAL ABDIMAS KESEHATAN TERPADU Vol. 3 No. 2 (2024): Jurnal Abdimas Kesehatan Terpadu
Publisher : Fakultas Kedokteran Gigi, Universitas Trisakti bekerjasama dengan Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jakt.v3i2.21744

Abstract

COVID-19 cases in Indonesia have increased to require comprehensive efforts in case management and efforts to break the chain of transmission. The community in the RW. 07 Benteng Sub-district, Warudoyong District, Sukabumi City have oral health problems such as cavities, swelling of the gum, and bad breath. At the time of the COVID-19 pandemic, people are terrified to go to the dentist because of the information that dental care considers having a higher risk of COVID-19. Based on the above problems, the FKG Trisakti University’s Team provided education in counseling and training to the community in RW. 07 Sukabumi City. The case emergency, even though during the COVID-19 pandemic to get dental care, so as not to aggravate further the situation where unchecked, the swelling might interfere with breathing and endanger personal safety. they are also informed about the management to go to the dentist. To minimize the transmission of the virus such as always using a mask, carrying out the WHO standard 6-step hand washing procedure, sneezing or coughing ethics, and doing physical restrictions. While in the waiting room, also when in the practice room, the dentist and other health teams use Personal Protective Equipment (PPE), disinfection, cleaning, and handling of tools and the patient rinses his mouth with Povidone-iodine mouthwash before starting treatment. We can maintain Oral hygiene and teeth remain healthy if brushing teeth is doing appropriately, using dental floss, mouthwash from natural ingredients such as betel leaf, and avoiding foods that contain lots of sugar.
Apium graveolens leaf ethanolic extract triggers apoptosis in human tongue cancer cells via caspase-3 and poly(ADP-ribose) polymerase pathways: An in vitro study Sandra, Ferry; Hartono, Tiffany; Hayuningtyas, Ria A.; Ranggaini, Dewi; Halim, Johni; Lee, Kyung H.
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1634

Abstract

Recent advances in cancer treatment have focused on developing alternative therapies with reduced adverse effects. Chemoprevention using natural products derived from plants has gained significant attention. Apium graveolens has demonstrated anticancer properties against various cancer cell types, suggesting its potential efficacy against tongue cancer cells. The aim of this study was to evaluate the cytotoxic effects and mechanisms of action of Apium graveolens leaf ethanolic extract (AGLEE) on the HSC-3 tongue cancer cell line. The leaves were processed and extracted with 70% ethanol to obtain an ethanolic extract. HSC-3 cells were cultured, subjected to starvation, and pre-treated with or without Z-DEVD-FMK, a caspase-3 inhibitor. Subsequently, the cells were treated with or without doxorubicin or varying concentrations of AGLEE. To assess cell viability and apoptosis, MTT and sub-G1 assays were performed. Additionally, treated HSC-3 cells were collected, lysed, and analyzed for levels of cleaved-caspase-3 and cleaved-poly (ADP-ribose) polymerase (cleaved-PARP) using ELISA. The inhibitory concentration (IC50) value of AGLEE for reducing viable HSC-3 cells was determined to be 48.29 μg/mL. AGLEE significantly decreased HSC-3 cell viability and increased the percentage of apoptotic cells. It exhibited a concentration-dependent reduction in cell viability and an increase in apoptosis. Furthermore, the extract elevated the levels of cleaved-caspase-3 and cleaved-PARP in HSC-3 cells. Pre-treatment with Z-DEVD-FMK reduced the levels of cleaved-caspase-3 and cleaved-PARP induced by AGLEE. Taken together, AGLEE could be proposed as a potential natural therapeutic agent by inducing apoptosis through the caspase-3/PARP pathway in tongue cancer cells.
PENYULUHAN GURU-GURU SEKOLAH MENENGAH TENTANG GANGGUAN MUSKULOSKELETAL PADA REMAJA Marpaung,SpPros.,PhD, Carolina Damayanti; Hanin, Isya; Anggraini, Wita; Juliawati, Mita; Ranggaini, Dewi; Krisna, Yohanes; Michelle, Michelle; Putri, Ni Luh
Jurnal Abdi Masyarakat Indonesia (JAMIN) Vol 6 No 2 (2024): JURNAL ABDI MASYARAKAT INDONESIA (JAMIN)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jamin.v6i2.19187

Abstract

Musculoskeletal disorders are common issues that affect various age groups, including children and adolescents. In dentistry, a frequently encountered musculoskeletal disorder is temporomandibular disorder, which can significantly impact the quality of life of those affected. Schools play a crucial role in preventing and detecting musculoskeletal disorders among students. However, the literature indicates that teachers' knowledge regarding musculoskeletal disorders generally remains relatively low. Therefore, education and training programs must enhance teachers' understanding of these issues. As part of its commitment to health education, the Community Service Team (PkM) of Universitas Trisakti conducted an awareness program for 100 secondary school teachers at IPEKA Tomang. The program was carried out in two stages, focusing on general musculoskeletal and orofacial disorders. The evaluation results showed an improvement in teachers' understanding of both topics, which is expected to contribute to the prevention and early management of musculoskeletal disorders in schools. 
Co-Authors Ferry Sandra Halim, Johni Hartono, Tiffany Hayuningtyas, Ria A. Himawan Halim Isya Hanin Juliawati, Mita Krisna, Yohanes Lee, Kyung H. Marpaung,SpPros.,PhD, Carolina Damayanti Michelle, Michelle N Santosa, Didi Ni Luh Putri Sadono, Melanie Wita Anggraini