Claim Missing Document
Check
Articles

Found 3 Documents
Search

Antioxidant Activity Test On Ethanol Extract Of Cassava Leaves (Manihot Esculenta C.) Using DPPH Method Husain, Muhammad Hafizh; Febrianti, Dewi Retno; Salsabillah, Salma; Rolita, Ninda Norma; Amrullah, Kammal Nizam; Bawani, Elen Ayu; Ramadhani, Lailatul; Pratiwi, Lidia Wahyu; Yaqin, Ngainul; Jayanti, Angelina; Rafsanjani, Ramizard; Januarista, Terra; Faisal, Faisal; Ramadhan, Majida
Biopedagogia Vol 6, No 2 (2024): November
Publisher : Program Studi Pendidikan Biologi Universitas Borneo Tarakan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35334/biopedagogia.v6i2.5533

Abstract

Cassava leaves (Manihot esculenta Crantz) are herbs used in traditional medicine. Cassava leaves contain secondary metabolite chemicals such as vitamin C, flavonoids, tannins, saponins, and triterpenes. Cassava leaves are pharmacologically active as anti-inflammatory, antibacterial, and antioxidants. To identify the sample's active antioxidant components using the DPPH technique. The DPPH method is a method of determining the antioxidant activity of a sample by examining its capacity to neutralize free radicals of the 2,2-diphenyl-1-picrylhydrazyl molecule. The antioxidant activity of quercetin from cassava leaf extract (Manihot esculenta Crantz) yielded an IC50 value of 210.33. The IC50 value shows that cassava leaves (Manihot esculenta Crantz) have modest antioxidant lower. Cassava leaves (Manihot esculenta Crantz) have antioxidant activity of 210.33 g/mL so they are included in the weak category in this study.
Potensi Antikapang Ekstrak Etanol Daun Benalu teh (Scurrula atropurpurea (Bl.) Dans) terhadap Candida albicans Secara in Vitro Husain, Muhammad Hafizh; Sjakoer, Nour Athiroh Abdoes; Faisal, Faisal
BioEksakta : Jurnal Ilmiah Biologi Unsoed Vol 7 No 2 (2025): BioEksakta
Publisher : Fakultas Biologi Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.bioe.2025.7.2.15801

Abstract

Benalu teh (Scurrula atropurpurea (Bl.) Dans) merupakan tanaman yang mengandung senyawa bioaktif seperti flavonoid, alkaloid, tanin, fenolik, dan terpenoid yang berpotensi sebagai antifungi alami. Candida albicans adalah jamur oportunistik yang secara alami terdapat dalam tubuh manusia, namun dapat menyebabkan infeksi apabila terjadi ketidakseimbangan sistem imun atau perubahan lingkungan mikroba. Penelitian ini bertujuan untuk mengetahui efektivitas ekstrak etanol daun benalu teh dalam menghambat pertumbuhan Candida albicans secara in vitro. Metode yang digunakan adalah eksperimen dengan desain Rancangan Acak Lengkap (RAL) menggunakan teknik pengenceran bertingkat (serial dilution) dan metode sebar (spread plate) pada media Potato Dextrose Broth (PDB) dan Potato Dextrose Agar (PDA). Hasil penelitian menunjukkan bahwa ekstrak mulai efektif terhadap Candida albicans pada konsentrasi ≥12,5%, dengan Kadar Hambat Minimum (KHM) optimal pada 6,25% (OD 1,310 nm). Uji ANOVA menunjukkan adanya perbedaan yang signifikan terhadap pertumbuhan Candida albicans (p<0,05). Ekstrak etanol daun benalu teh memiliki potensi sebagai antifungi terhadap Candida albicans. Kata kunci : Antikapang, Benalu teh, Candida albicans.
Phytochemical Screening and Determination of Total Flavonoid Content of Keji Beling Leaves Ethanol Extract (Strobilanthes crispa Bl.) Mahyantika, Seftya Putri; Husain, Muhammad Hafizh; Nirwana, Linggar; Aldina, Devana Rahma; Gemilang, Satria; Nafisa, Nafisa; Ramadhan, Majida; Sjakoer, Nour Athiroh Abdoes; Faisal, Faisal
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.219-224

Abstract

This study aims to determine the total flavonoid content in the ethanol extract of keji beling (Strobilanthes crispa) leaves using the UV-Vis spectrophotometric method with AlCl3 reagent. The research process includes maximum wavelength testing, preparation of quercetin standard solution, and analysis of total flavonoid levels. The results showed that the total flavonoid content in the extract was 144.347 ± 134.854 mg QE/g extract, with an extract yield of 0.4% and extract moisture content of 5.256%, which showed good potential in preventing the growth of microorganisms. Phytochemical screening revealed the presence of alkaloids, flavonoids, and tannins, while saponins, triterpenoids, and steroids were not detected. These findings confirm the importance of secondary metabolite compounds in plants and the potential of keji beling leaf extract as a source of active compounds with health benefits, including antioxidant and antibacterial activities. This study provides a basis for further research into the medical applications of this plant extract.