Permana, Annes Rindy
Institute Of Technology, Science, And Health RS Dr. Soepraoen

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PERBEDAAN WAKTU PULIH SADAR PENGGUNAAN PESFLURAN DAN SEVOFLURAN ANESTESI BEDAH MODIFIED RADICAL MASTECTOMY Rodli, Muhammad; MR, Merisdawati; Negoro, Widigdo Rekso; Permana, Annes Rindy
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 1 (2025): APRIL 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i1.40826

Abstract

Tujuan penelitian ini mengetahui perbedaan waktu pulih sadar antara penggunaan anestesi inhalasi desfluran dan sevofluran pada pasien general anestesi dengan bedah modified radical mastectomy di Rumah Sakit Tk II 17.05.01 Marthen Indey. Penelitian ini menggunakan desain korelasi dengan pendekatan cross sectional. Dalam penelitian ini, peneliti menggunakan 100 populasi yang merupakan pasien Rumah Sakit Tk II 17.05.01 Marthen Indey yang menjalani tindakan anestesi desfluran dan sevofluran. Dari 100 populasi tersebut, kemudian ditentukan sampel penelitian dengan menggunakan rumus slovin dan diperoleh sampel sebanyak 76. Dari total sampel yang diperoleh, sampel tersebut kemudian dibagi menjadi dua kelompok, sebanyak 38 responden sebagai sampel desfluran dan 38 sisanya sebagai sampel sevofluran. Dari 76 responden diperoleh sebanyak 38 responden menjalani tindakan anestesi desfluran, dimana sebanyak 97,4% responden memiliki waktu pulih sadar cepat dan sisanya hanya 2,6% responden memiliki waktu pulih sadar lambat. Sebanyak 38 responden menjalani tindakan anestesi sevofluran, dimana terdapat 78,9% responden memiliki waktu pulih sadar cepat dan sisanya sebanyak 21,1% responden memiliki waktu pulih sadar lambat. Hasil pengujian statistic dengan Teknik Chi-Square diperoleh nilai =0,014 yang berarti bahwa terdapat perbedaan waktu pulih sadar antara penggunaan anestesi desfluran dengan sevofluran pada pasien general anestesi dengan bedah modified radical mastectomy di Rumah Sakit Tk II 17.05.01 Marthen Indey. Berdasarkan hasil perbedaan waktu pulih sadar pasien dan hasil pengujian statistic pada data penelitian, dapat disimpulkan bahwa terdapat perbedaan waktu pulih sadar pasien yang menjalani tindakan anestesi desfluran dan sevofluran dengan Teknik bedah modified radical mastectomy di Rumah Sakit Tk II 17.05.01 Marthen Indey.Tujuan penelitian ini mengetahui perbedaan waktu pulih sadar antara penggunaan anestesi inhalasi desfluran dan sevofluran pada pasien general anestesi dengan bedah modified radical mastectomy di Rumah Sakit Tk II 17.05.01 Marthen Indey. Penelitian ini menggunakan desain korelasi dengan pendekatan cross sectional. Dalam penelitian ini, peneliti menggunakan 100 populasi yang merupakan pasien Rumah Sakit Tk II 17.05.01 Marthen Indey yang menjalani tindakan anestesi desfluran dan sevofluran. Dari 100 populasi tersebut, kemudian ditentukan sampel penelitian dengan menggunakan rumus slovin dan diperoleh sampel sebanyak 76. Dari total sampel yang diperoleh, sampel tersebut kemudian dibagi menjadi dua kelompok, sebanyak 38 responden sebagai sampel desfluran dan 38 sisanya sebagai sampel sevofluran. Dari 76 responden diperoleh sebanyak 38 responden menjalani tindakan anestesi desfluran, dimana sebanyak 97,4% responden memiliki waktu pulih sadar cepat dan sisanya hanya 2,6% responden memiliki waktu pulih sadar lambat. Sebanyak 38 responden menjalani tindakan anestesi sevofluran, dimana terdapat 78,9% responden memiliki waktu pulih sadar cepat dan sisanya sebanyak 21,1% responden memiliki waktu pulih sadar lambat. Hasil pengujian statistic dengan Teknik Chi-Square diperoleh nilai =0,014 yang berarti bahwa terdapat perbedaan waktu pulih sadar antara penggunaan anestesi desfluran dengan sevofluran pada pasien general anestesi dengan bedah modified radical mastectomy di Rumah Sakit Tk II 17.05.01 Marthen Indey. Berdasarkan hasil perbedaan waktu pulih sadar pasien dan hasil pengujian statistic pada data penelitian, dapat disimpulkan bahwa terdapat perbedaan waktu pulih sadar pasien yang menjalani tindakan anestesi desfluran dan sevofluran dengan Teknik bedah modified radical mastectomy di Rumah Sakit Tk II 17.05.01 Marthen Indey.
PERBEDAAN EFEK EPHEDRINE 10 MG DAN PHENYLEPRINE 50 MG DALAM TATALAKSANA HIPOTENSI PADA SECTIO CAESAREA DENGAN ANESTESI SPINAL Sintara, Sindu; Syamsudin, Syamsudin; Rodli, Muhammad; Negoro, Widigdo Rekso; Permana, Annes Rindy
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 1 (2025): APRIL 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i1.41287

Abstract

Anestesi spinal merupakan salah satu teknik anestesi untuk tindakan Sectio caesarea. Teknik ini dilakukan dengan menyuntikkan obat anestesi lokal ke subarachnoid yang bertujuan untuk menghilangkan sensasi nyeri saat dilakukan tindakan pembedahan. Namun, anestesi spinal dapat menyebabkan komplikasi salah satunya yang paling sering terjadi yakni hipotensi. Ephedrine 10 mg dan phenyleprine 50 mg dianggap dapat membantu meningkatkan tekanan darah pasien yang mengalami hipotensi. Penelitian ini bertujuan menganalisis untuk mengetahui perbedaan pengaruh antara ephedrine 10 mg dengan phenylephrine 50 mg pada pasien Sectio caesarea pasca tindakan anestesi spinal. Metode yang digunakan yakni quasy eksperimen dengan desain penelitian pre-experimental one group pretest-postest. Populasi dalam penelitian ini merupakan pasien RSU Mahkota Bidadari Langkat yakni sebanyak 100 pasien. Dari 100 pasien dipilih 60 pasien yang digunakan sebagai sampel penelitian dengan menggunakan teknik total sampling. Analisis menggunakan teknik univariat dan bivariat dengan teknik pengujian uji independent sample t-test. Hasil penelitian ini menunjukkan terdapat perbedaan tekanan darah pasien Sectio caesarea setelah diberikan ephedrine 10 mg dan phenyleprine 50 mg di RSU Mahkota Bidadari Langkat dengan nilai p=0,000 < 0,05. Tekanan darah sistolik dengan nilai t-hitung = -4,079 dan tekanan darah diastolik dengan nilai p=0,000 < 0,05 dan nilai t-hitung = -3,433.
Preoperative Anxiety Levels and the Incidence of Postoperative Nausea and Vomiting in Patients Undergoing General Anesthesia Rekso Negoro, Widigdo; Sintara, Sindu; Rindy Permana, Annes; Rodli, Muhammad; Priyonggo, Reko; Suryanto
Jurnal Kesehatan Masyarakat Vol. 21 No. 2 (2025)
Publisher : Universitas Negeri Semarang in collaboration with Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI Tingkat Pusat) and Jejaring Nasional Pendidikan Kesehatan (JNPK)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v21i2.27115

Abstract

Postoperative nausea and vomiting (PONV) are common complications after general anesthesia, negatively impacting patient comfort, recovery, and hospital stay. While many factors contribute to PONV, psychological aspects such as preoperative anxiety are often underestimated despite their influence on postoperative outcomes. This study aimed to analyze the relationship between preoperative anxiety levels and the incidence of PONV in patients undergoing surgery under general anesthesia. Using a cross-sectional design, 45 elective surgical patients were assessed for anxiety using the Hamilton Anxiety Rating Scale (HARS), and PONV incidence was recorded within 24 hours post-surgery. Chi-square analysis revealed a significant association between anxiety levels and PONV occurrence (p = 0.002). Among patients with moderate to severe anxiety, 73.3% experienced PONV, compared to only 26.7% among those with mild anxiety. These findings indicate that higher preoperative anxiety increases the risk of PONV. Therefore, integrating psychological assessment and anxiety management into perioperative care is crucial to reducing postoperative complications and improving anesthetic outcomes through a more holistic patient care approach.
Surgical Procedures and Team Compliance with the Surgical Safety Checklist Budi Prasetyo, Agus; Negoro, Widigdo Rekso; Rodli, Muhammad; Sintara, Sindu; Permana, Annes Rindy
Jurnal Keperawatan Profesional (KEPO) Vol. 6 No. 2 (2025): Volume 6 Nomor 2 November 2025
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/kepo.v6i2.1590

Abstract

Patient safety is a critical component of surgical procedures, with the Surgical Safety Checklist (SSC) playing a key role in minimizing medical errors. However, its implementation in healthcare settings continues to face challenges in medical team compliance. This study aimed to examine the relationship between the type of surgical procedure and the level of compliance of medical teams in implementing SSC. An analytic survey with a cross-sectional approach was conducted at a maternal and child specialty hospital in urban Yogyakarta. Data were collected through observation of 65 surgical procedures using a checklist based on the three SSC phases (sign-in, time-out, sign-out), and analyzed using the chi-square test. Results showed elective surgeries were more dominant (55,4%), with the majority of patients undergoing cesarean section (84,6%). A significant association was found between surgery type and compliance during the time-out (p-value = 0,004) and sign-out (p-value = 0,011) phases, but not during the sign-in phase (p-value = 0,195). Overall, only 27,7% of surgeries were performed with full SSC compliance. These findings indicate that surgical procedure type significantly influences SSC compliance, particularly in the time-out and sign-out phases, and underline the need for targeted system strengthening through structured training, standardized workflow integration, and continuous compliance monitoring to improve patient safety outcomes.
Comparative effects of desflurane and sevoflurane on recovery time in patients undergoing modified radical mastectomy: a cross-sectional study Muhammad Rodli; Suryanto Suryanto; Reko Priyonggo; Sindu Sintara; Annes Rindy Permana; Widigdo Rekso Negoro
International Journal of Public Health Science (IJPHS) Vol 15, No 2: June 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i2.26903

Abstract

Fast and predictable recovery is essential in breast cancer surgery, yet comparative evidence on inhalation anesthetics within Indonesian clinical settings remains limited. This study compared the effectiveness of desflurane and sevoflurane on early recovery time after modified radical mastectomy. A cross-sectional design was applied to 76 ASA I-II female patients who received standardized induction, maintenance, and Aldrete-based recovery assessment. Recovery was categorized as fast (≤10 minutes) or delayed (>10 minutes). Statistical analysis used Chi-square testing, supported by effect size and risk ratio estimation. Desflurane demonstrated significantly faster recovery than sevoflurane (97.4% vs 78.9%, p = 0.014). The association showed a moderate effect size (Cramér’s V = 0.30), and patients receiving sevoflurane were substantially more likely to experience delayed recovery (RR = 8.3). These results align with recent studies highlighting desflurane’s lower blood-gas solubility and faster elimination profile. The homogeneous sample and standardized anesthetic protocol strengthen internal validity. However, the non-randomized design, purposive sampling, and absence of documented adverse events limit generalizability. Desflurane may offer practical benefits in improving post-anesthesia care unit (PACU) efficiency and surgical throughput in high-volume settings. Further multicenter randomized studies are recommended to confirm these findings and explore broader clinical implications.
Hemodynamic stabilization in cesarean section patients administered spinal anesthesia: a quasi-experimental study comparing ephedrine and phenylephrine Sindu Sintara; Annes Rindy Permana; Widigdo Rekso Negoro; Suryanto Suryanto; Reko Priyonggo; Muhammad Rodli
International Journal of Public Health Science (IJPHS) Vol 15, No 2: June 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i2.26957

Abstract

This quasi-experimental research aimed to compare the effects observed following the administration of ephedrine 10 mg and phenylephrine 50 mg administered as therapeutic bolus doses for the management of intraoperative hypotension due to spinal anesthesia in cesarean section. The study involved 60 parturients who developed intraoperative hypotension during spinal anesthesia, who were divided into two groups treated with either phenylephrine or ephedrine. Maternal blood pressure, including systolic and diastolic values, was assessed pre- and post- vasopressor administration and analyzed using descriptive statistics, normality testing, and independent-samples t-tests. Both vasopressors were associated with increased maternal blood pressure following intervention, with no significant differences observed at baseline. However, between-group comparisons revealed statistically significant differences in post-intervention systolic and diastolic blood pressure (p < 0.05), indicating distinct hemodynamic response profiles. These findings demonstrate the effectiveness of both ephedrine and phenylephrine in treating hypotension associated with spinal anesthesia; vasopressor selection influences maternal blood pressure outcomes. From a practical perspective, this study provides clinically relevant evidence to inform anesthetic decision-making in maternal healthcare services, particularly in settings where therapeutic bolus administration is routinely utilized for the management of hypotension associated with spinal anesthesia.
Association of body mass index and age as risk factors for post-anesthetic shivering in mastectomy patients under general anesthesia in East Java, Indonesia Reko Priyonggo; Muhammad Rodli; Suryanto Suryanto; Annes Rindy Permana; Widigdo Rekso Negoro; Sindu Sintara
International Journal of Public Health Science (IJPHS) Vol 15, No 2: June 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i2.26908

Abstract

Intraoperative hypothermia and post-anesthetic shivering (PAS) remain frequent complications in oncologic surgery under general anesthesia, yet evidence integrating intraoperative temperature changes with PAS severity in mastectomy patients is limited. This study aimed to evaluate intraoperative temperature profiles, determine the incidence and severity of PAS, and analyze the association between age, body mass index (BMI), and PAS among radical mastectomy patients. A cross-sectional observational study was conducted involving 36 women undergoing radical mastectomy with endotracheal general anesthesia. Core temperature was measured at 30 and 60 minutes intraoperatively, and PAS was assessed using the bedside shivering assessment scale (BSAS) upon admission to the recovery room. Moderate intraoperative hypothermia was observed in 72.2% of patients at 60 minutes, while PAS occurred in 30.6% of cases. Significant associations were identified between PAS and BMI (p = 0.001), as well as age (p = 0.026). Moderate-to-severe shivering (BSAS scores 2-3) was more frequently observed among underweight and elderly patients. This study provides novel evidence by linking intraoperative hypothermia patterns with PAS severity using BSAS in mastectomy patients. Clinically, the findings support structured perioperative temperature monitoring and the implementation of risk-based warming protocols, particularly for patients with low BMI and advanced age.
Effectiveness of hypnotherapy as complementary intervention in reducing post-cesarean pain: A PRISMA-based systematic review of literature released during the 2015-2024 period Annes Rindy Permana; Widigdo Rekso Negoro; Sindu Sintara; Muhammad Rodli; Suryanto Suryanto; Reko Priyonggo
International Journal of Public Health Science (IJPHS) Vol 15, No 2: June 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i2.26893

Abstract

Cesarean section is a common surgical procedure often associated with moderate to severe postoperative pain. Hypnotherapy has been proposed as a complementary, non-pharmacological intervention; however, evidence specific to post-cesarean pain management remains limited. The purpose of this PRISMA-based systematic review was to evaluate hypnotherapy as an intervention for reducing postoperative pain associated with cesarean section. Literature searches were conducted in Google Scholar and PubMed for studies published between 2015 and 2024 using predefined inclusion and exclusion criteria. From 326 identified records, four studies met all eligibility criteria and were included in the qualitative synthesis. Despite heterogeneity in study design and intervention protocols, all included studies consistently reported reductions in postoperative pain intensity among participants receiving hypnotherapy compared with standard postoperative care, with pain outcomes primarily measured using validated scales such as the Numerical Rating Scale. These findings suggest that hypnotherapy may support conventional analgesic strategies as an adjunctive intervention during early postoperative recovery. Nevertheless, the scarcity of existing research and the presence of methodological limitations suggest the need for rigorously designed randomized controlled trials to provide more robust evidence.
Operation type and phase specific compliance with WHO surgical safety guidelines checklist at the mother and child hospital Agus Budi Prasetyo; Ircham Saifudin; Widigdo Rekso Negoro; Muhammad Rodli; Sindu Sintara; Annes Rindy Permana
International Journal of Public Health Science (IJPHS) Vol 15, No 2: June 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i2.26904

Abstract

The surgical safety checklist (SSC) is a recognized tool for enhancing patient safety by reducing surgical complications and mortality. While its benefits are well established, effective implementation depends on consistent adherence by the medical team. This study examined the relationship between surgical procedure type and team compliance with SSC in the central operating room of a maternal and child hospital in Yogyakarta. Using a quantitative cross-sectional design, data were collected from 65 observed operations out of 148 total procedures, including elective and emergency cases. Compliance was evaluated in three SSC phases: sign-in, time-out, and sign-out. Correlation was analyzed using chi-square tests. The results showed no significant relationship in the sign-in phase (p = 0.195), but significant correlations were found in the time-out (p = 0.004) and sign-out (p = 0.011) phases. Overall, a significant association was identified between type of surgery and SSC compliance (p = 0.006). This study concludes that SSC compliance remains suboptimal, particularly in the initial phase. Elective procedures demonstrated higher compliance than emergency cases. Strengthening a culture of safety and promoting interdisciplinary training are essential strategies to improve SSC adherence and elevate surgical care quality.