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All Journal Caring : Jurnal Pengabdian Masyarakat Pharmaceutical Sciences and Research (PSR) International Journal of Radiology and Imaging
Fahanani, Agwin Fahmi
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Anthocyanin-Rich Extract from Purple Sweet Potatoes Modified Body Weight, Visceral Fat and Circulatory IL-10 in Stressed-Mice Kurnianingsih, Nia; Rahma, Oktivani Adelathifa; Prayogo, Nabila Putri; Rayhanna, Qanitha Ailsya; Fahanani, Agwin Fahmi; Suprapto, Ratih Paramita; Prakosa, Ardani Galih; Ratnawati, Retty
Pharmaceutical Sciences and Research Vol. 11, No. 3
Publisher : UI Scholars Hub

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Abstract

Stress-induced inflammation and oxidative stress mechanisms thus plant bioactive compounds as anti-inflammation and antioxidants are placed as novel strategies to resist the adverse effects of stress. Purple sweet potatoes (PSP) as a rich source of macronutrients and anthocyanin showed health benefits as neuroprotective and metabolic diseases. However, limited research explored the effect of PSP extract on stressed animal models. This study aimed to evaluate the bioactive compound analysis of PSP and the effect on body weight gain (BW), visceral fat (VF), and interleukin-10 (IL-10) of stressed model mice. Adult male BALB/c mice (6-8 weeks) were divided into control (CTRL), and stress (STR), stress+anthocyanin-rich extract (ANC) of PSP dose 10, 20, and 40 mg/kgBW. Stress was exposed as restraint stress for 2 hours/day for 14 days. The ANC was administered once a day orally. The IL-10 was measured by enzyme-linked immunosorbent assay (ELISA). Qualitative plant compound analysis showed the presence of flavonoids, alkaloids, phenolics, glycosides, and tannins in PSP extract. The PSP extract also contains a high level of total anthocyanin, 2468.9 ± 159.38 mg/l, and high antioxidant activity. This study observed tendencies to decrease BW and VF following ANC dose of 10 mg/kgBW treatment. The administration of ANC significantly increased the level of circulatory IL-10 cytokine. In conclusion, an anthocyanin-rich extract of PSP modified BW, VF, and IL-10 levels of restraint-stressed model mice.
Pojok kasih lansia: optimizing the quality of life for older adults in lumajang regency through the development of an elderly-friendly park Kumboyono, Kumboyono; Dewi, Elvira Sari; Dewi, NI Putu Wahyu Eastiya; Febriano, Luis Figo; Anwar, Mochamad Saiful; Syadilla, Iryne Putri; Setyaningsih, Diva Ayu; Nadhifah, Umi; Rahmat, Basuki; Mayasari, Linda; Fathoni, Jazimah Nur; Kristianingrum, Niko Dima; Swastirani, Astika; Fahanani, Agwin Fahmi
Caring: Jurnal Pengabdian Masyarakat Vol 5, No 1 (2025): CARING Jurnal Pengabdian Masyarakat (April 2025)
Publisher : Caring: Jurnal Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.caringjpm.2025.005.01.3

Abstract

The increasing elderly population in Lumajang Regency, especially in Yosowilangun District, indicates progress in life expectancy but also brings challenges related to elderly care and dependency. To address these issues, a women's empowerment program was conducted in 2023 through the mentoring of Elderly Care Mothers, focusing on promoting elderly independence and caregiver support. In 2024, the initiative continued with the development of a Senior-Friendly Park equipped with ergonomic seating, sensory therapy, and recreational facilities under the concept of the Elderly Care Corner. This program aimed to improve the quality of life of older adults, enhance community involvement, and support caregiving efforts. The activities included park construction, public engagement, capacity-building for elderly care cadres, and the development of educational materials for caregivers. The outcomes demonstrated active participation of 75 elderly individuals within the first two months, a 32 percent increase in knowledge among 20 trained elderly care cadres, and reduced workload reported by 68 percent of caregivers. Improvements were also recorded in quality of life scores, particularly in life satisfaction and daily activities. Qualitative findings highlighted increased social interaction, motivation, and caregiver confidence. This initiative has encouraged replication in other villages and is expected to contribute positively to the well-being of the elderly population in Lumajang Regency.
THE RELATIONSHIP BETWEEN BREAST VOLUME AND BREAST MALIGNANCY IN MAMMOGRAPHY Lathifa, Jauza Atsil; Yueniwati, Yuyun; Fahanani, Agwin Fahmi
International Journal of Radiology and Imaging Vol. 1 No. 02 (2022): International Journal of Radiology and Imaging
Publisher : Department of Radiology, Medical Faculty, University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (381.462 KB) | DOI: 10.21776/ub.ijri.2022.001.02.5

Abstract

Breast cancer is a major global public health problem and the most common type of cancer. The incidence of cases in Indonesia are about 42.1 per 100.000 population in 2019. There are multiple risk factors that underlie breast cancer malignancy. However, breast volume has not been yet included as a risk factor for breast cancer. The aim of this study is to analyze the association between breast volume and breast malignancy. This study is a cross-sectional study obtaining breast volume and BI-RADS score by performing mammography assessment at dr. Saiful Anwar General Hospital, Malang. The inclusion criteria were women aged > 40 years and excluded those who have mammography contraindications such as pregnancy and breast-feeding. The parameters for calculating breast volume were the width, height, and compression thickness, and the BI-RADS category (0 – 6) was used to determine the malignancy.   There is no significant association using the non-parametric analytic test Kruskal Wallis analytic test (p = 0.273 , p < 0.05) and a very weak negative correlation based on the correlation test Spearmanis correlation test (-0.127). There is no association between breast volume and the risk of malignancy based on BI-RADS mammography.
Co-Authors Anwar, Mochamad Saiful Ardani Galih Prakosa, Ardani Galih Basuki Rahmat Masdi Siduppa Dewi, NI Putu Wahyu Eastiya Elvira Sari Dewi Fathoni, Jazimah Nur Febriano, Luis Figo Kristianingrum, Niko Dima Kumboyono Kumboyono Kurnianingsih, Nia Lathifa, Jauza Atsil linda mayasari, linda Nadhifah, Umi Prayogo, Nabila Putri Rahma, Oktivani Adelathifa Rayhanna, Qanitha Ailsya Retty Ratnawati Setyaningsih, Diva Ayu Suprapto, Ratih Paramita Swastirani, Astika Syadilla, Iryne Putri Yuyun Yueniwati