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All Journal JURNAL FARMASIMED (JFM) Jurnal EduHealth Fakumi Medical Journal The Indonesian Journal of General Medicine
Irna Diyana Kartika Kamaluddin
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Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Journal : JURNAL FARMASIMED (JFM)

 1 
Antibacterial Activity Test of 96% Ethanol Extract of Red Ginger (Zingiber officinale var. rubrum) Against the Growth of StreptococcusPneumoniae Bacteria Harry Nugraha Bachtiar; Irna Diyana Kartika Kamaluddin; Iin Widya Ningsi; Adriani; Dwi Anggita
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/6z84gr80

Abstract

Abstract Background: Pneumonia is an infectious disease with a high global prevalence that contributes significantly to mortality in children and adults. Red ginger (Zingiber officinale var. rubrum), a traditional Indonesian medicinal plant, has been identified as having antibacterial, antioxidant, and anti-inflammatory properties. Some of its natural constituents, such as flavonoids, have shown antimicrobial activity with a low toxicity profile. Therefore, the phytochemical content in red ginger is assumed to be able to combat Streptococcus pneumoniae bacteria, which is one of the main etiologies of Pneumonia. Objective: Evaluating the potential of 96% ethanol extract of red ginger (Zingiber officinale var. rubrum) as an antimicrobial agent in inhibiting the growth of Streptococcus pneumoniae bacteria. Method: This study applied a true experimental approach with a post-test design to evaluate the effectiveness of 96% ethanol extract of red ginger (Zingiber officinale var. rubrum) as an agent that inhibits the growth of Streptococcus pneumoniae bacteria. The method used was the disc diffusion method (Kirby-Bauer). Results: The study showed that the ethanol extract of red ginger (Zingiber officinale var. rubrum) exhibited antibacterial activity; however, its effectiveness in inhibiting the growth of Streptococcus pneumoniae was not significant.Conclusion: The 96% ethanol extract of red ginger (Zingiber officinale var. rubrum) demonstrated resistance, showing only minimal inhibitory activity against Streptococcus pneumoniae. This condition contrasts with the positive control, chloramphenicol, which produced a significant inhibition zone and was categorized as sensitive. Therefore, the effectiveness of red ginger extract in inhibiting the growth of this bacterium is considerably lower than that of chloramphenicol.
Co-Authors Abdul Mubdi Ardiansar Adriani Berry Erida Hasbi Dwi Anggita Harry Nugraha Bachtiar Ida Royani Iin Widya Ningsi Indah Lestari Daeng Kanang Irmayanti Haidir Bima Irmayanti Irmayanti, Irmayanti M Farhan Anwar Mustari, Ikhsanul Fauzi Nadila Ardyani Nahardi Nurfadhillah Khalid Sri Julyani