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All Journal JURNAL FARMASIMED (JFM) Fakumi Medical Journal The Indonesian Journal of General Medicine KREATIF: Jurnal Pengabdian Masyarakat Nusantara
Irna Diyana Kartika Kamaluddin
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Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Veterinary

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Hubungan antara Rasio Neutrofil Limfosit dengan Viral Load pada Pasien HIV Mustari, Ikhsanul Fauzi; Irna Diyana Kartika Kamaluddin; Irmayanti Haidir Bima; Sri Julyani; Abdul Mubdi Ardiansar
Fakumi Medical Journal: Jurnal Mahasiswa Kedokteran Vol. 5 No. 1 (2025): Maret
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/fmj.v5i1.538

Abstract

Infeksi HIV menyebabkan gangguan sistem imun dengan berbagai manifestasi klinis, termasuk peningkatan inflamasi yang dapat diukur melalui rasio neutrofil-limfosit (NLR). Penelitian ini bertujuan untuk menganalisis hubungan antara viral load dengan NLR pada pasien HIV/AIDS. Penelitian ini menggunakan desain cross-sectional dengan 50 pasien HIV/AIDS di RSUD Kota Kendari. Data dikumpulkan dari rekam medis pasien, mencakup nilai NLR dan kadar viral load. Analisis hubungan antara variabel dilakukan menggunakan uji Chi-square. Hasil penelitian menunjukkan bahwa mayoritas responden memiliki NLR normal (<6) sebanyak 48 responden (96,0%) dan NLR tidak normal (≥6) sebanyak 2 responden (4,0%). Selain itu, sebanyak 43 responden (86,0%) memiliki viral load tidak terdeteksi (<50 copies/mL), sedangkan 7 responden (14,0%) memiliki viral load terdeteksi (≥50 copies/mL). Hasil uji statistik menunjukkan adanya hubungan yang signifikan antara NLR dan viral load (p = 0,000) dengan korelasi phi = 0,506, yang mengindikasikan hubungan yang kuat antara kedua variabel. Kesimpulannya, terdapat hubungan signifikan antara NLR dan viral load pada pasien HIV/AIDS, di mana peningkatan NLR berhubungan dengan tingginya viral load.
Transfusi Darah Dalam Pandangan Islam Nadila Ardyani Nahardi; Irna Diyana Kartika Kamaluddin; Nurfadhillah Khalid; Ida Royani
The Indonesian Journal of General Medicine Vol. 13 No. 1 (2025): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/gsczjq72

Abstract

Latar Belakang: Transfusi darah merupakan intervensi medis penting yang sering kali menjadi penentu keselamatan jiwa dalam kondisi darurat. Namun, dalam konteks Islam, praktik ini menimbulkan pertanyaan fiqhiyah karena Al-Qur’an dan Hadis tidak secara eksplisit membahasnya, sehingga diperlukan pendekatan ijtihadiyah untuk menetapkan hukumnya. Tujuan: Penelitian ini bertujuan untuk mengkaji perspektif hukum Islam terkait transfusi darah melalui telaah literatur ilmiah, serta mengidentifikasi pendapat ulama dan dalil syar’i yang mendukung praktik tersebut sebagai bentuk penyelamatan jiwa. Metode: Penelitian ini merupakan narrative literature review dengan metode pencarian data berdasarkan pendekatan PICO. Sumber data berasal dari jurnal ilmiah, laporan nasional, dan literatur relevan lainnya yang diperoleh melalui database elektronik seperti Google Scholar, PubMed, dan ResearchGate. Analisis dilakukan menggunakan tabel sintesis terhadap tujuh artikel terpilih. Hasil: Dari tujuh artikel yang dianalisis, enam membahas secara eksplisit hukum transfusi darah dalam Islam, dan satu artikel fokus pada manfaat donor darah secara medis. Sebagian besar artikel sepakat bahwa transfusi darah diperbolehkan, bahkan diwajibkan dalam kondisi darurat. Mayoritas ulama menganggap donor darah sebagai amal saleh, dengan dasar kaidah fikih “ad-darūrāt tubīḥu al-maḥẓūrāt” dan prinsip ḥifẓ al-nafs dalam maqāṣid al-syarī‘ah. Kesimpulan: Transfusi darah dalam pandangan Islam merupakan bentuk tolong-menolong dalam kebajikan  yang tidak hanya diperbolehkan, tetapi juga sangat dianjurkan dalam situasi darurat. Donor darah merupakan amal ibadah kontemporer yang mencerminkan nilai kemanusiaan dan solidaritas sosial. Disarankan agar edukasi mengenai transfusi darah ditingkatkan melalui kerja sama antara lembaga kesehatan dan institusi keagamaan untuk mendorong partisipasi masyarakat Muslim secara aktif dan sadar syar’i.
Antibacterial Activity Test of 96% Ethanol Extract of Red Ginger (Zingiber officinale var. rubrum) Against the Growth of StreptococcusPneumoniae Bacteria Harry Nugraha Bachtiar; Irna Diyana Kartika Kamaluddin; Iin Widya Ningsi; Adriani; Dwi Anggita
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/6z84gr80

Abstract

Abstract Background: Pneumonia is an infectious disease with a high global prevalence that contributes significantly to mortality in children and adults. Red ginger (Zingiber officinale var. rubrum), a traditional Indonesian medicinal plant, has been identified as having antibacterial, antioxidant, and anti-inflammatory properties. Some of its natural constituents, such as flavonoids, have shown antimicrobial activity with a low toxicity profile. Therefore, the phytochemical content in red ginger is assumed to be able to combat Streptococcus pneumoniae bacteria, which is one of the main etiologies of Pneumonia. Objective: Evaluating the potential of 96% ethanol extract of red ginger (Zingiber officinale var. rubrum) as an antimicrobial agent in inhibiting the growth of Streptococcus pneumoniae bacteria. Method: This study applied a true experimental approach with a post-test design to evaluate the effectiveness of 96% ethanol extract of red ginger (Zingiber officinale var. rubrum) as an agent that inhibits the growth of Streptococcus pneumoniae bacteria. The method used was the disc diffusion method (Kirby-Bauer). Results: The study showed that the ethanol extract of red ginger (Zingiber officinale var. rubrum) exhibited antibacterial activity; however, its effectiveness in inhibiting the growth of Streptococcus pneumoniae was not significant.Conclusion: The 96% ethanol extract of red ginger (Zingiber officinale var. rubrum) demonstrated resistance, showing only minimal inhibitory activity against Streptococcus pneumoniae. This condition contrasts with the positive control, chloramphenicol, which produced a significant inhibition zone and was categorized as sensitive. Therefore, the effectiveness of red ginger extract in inhibiting the growth of this bacterium is considerably lower than that of chloramphenicol.
Implementasi Program Bakti Sosial Mahasiswa Kedokteran sebagai Upaya Pemberdayaan Masyarakat: (Studi Kegiatan Fakultas Kedokteran UMI Bersama BEM KBMFK Universitas Muslim Indonesia Tahun 2025) Nasrudin Andi Mappaware; Irna Diyana Kartika Kamaluddin; Wawan Susilo; Faizul A; Andi Alamanda Irwan; M. Hamsah; Berry Erida Hasbi; Indah Lestari Daeng Kanang; Prema Hapsari Hidayati; Anna Sari Dewi; Dwi Anggita; Sidrah Darma; Nevi Sulvita Karsa; Zulfikri Khalil Novriansyah; Mohammad Reza Zainal Abidin; Muhammad Fauzul Azhim; Astra Budiati Nusrat; Muhammad Irsan Muflih Mundzir; Mufthiar Muhtar; Rizky Nurhumairah Sarifuddin; Wulan Purnamasyani S; Waode Inayatu Zahra Khairunnufus
KREATIF: Jurnal Pengabdian Masyarakat Nusantara Vol. 6 No. 2 (2026): Jurnal Pengabdian Masyarakat Nusantara
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/kreatif.v6i2.11053

Abstract

The Grand Social Service (Bakti Sosial Akbar) organized by KBMFK-UMI is an initiative that reflects the academic community's empathy and care for society, especially those in need. The activity aims to express a sense of social responsibility by providing various services to the community. These services include health checks, education, blood donation drives, mass circumcision, Basic Life Support (BLS) training, and the distribution of the Susu Anak Negeri (SUSAN) program. Through these efforts, the event seeks to alleviate some of the burdens faced by local communities while promoting health awareness and knowledge. In addition to offering essential services, this event is designed to strengthen relationships among students, faculty members, and the local residents by fostering a spirit of togetherness and collaboration. The implementation of this community service activity is made possible by the full support of the academic community at the Faculty of Medicine, Universitas Muslim Indonesia, ensuring that all activities are carried out effectively and precisely. It is expected that the positive outcomes of this event will not only benefit the community but also contribute to building a stronger sense of social solidarity and cooperation among all involved.
The Effectiveness of Red Ginger (Zingiber officinale var. rubrum) Extract Administration on Weight Reduction in Obese Mice (Mus musculus) Muhammad Erlangga Dewantara djoharam; Andi Alamanda Irwan; Asrini Safitri; Sigit Dwi Pramono; Irna Diyana Kartika Kamaluddin
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/d4pdxz92

Abstract

Background: Obesity is a complex condition influenced by various factors, including an imbalance between caloric intake and energy expenditure. Red ginger contains bioactive compounds such as gingerol, flavonoids, and essential oils that have the potential to reduce body weight through mechanisms related to fat metabolism regulation and anti-inflammatory activity. However, studies on the effectiveness of red ginger in reducing body weight in obese mice (Mus musculus) are still limited, thus further research is needed to confirm its benefits. Objective: To evaluate the effectiveness of red ginger extract in reducing body weight in obese mice (Mus musculus). Methods: This study employed a true experimental research design with full control over research variables, allowing direct observation of cause-and-effect relationships. The treatment was administered to obese mice to determine the impact of red ginger extract on body weight reduction. Results: The results showed that red ginger extract was effective in reducing the body weight of obese mice. The bioactive compounds in red ginger act through anti-obesity mechanisms, particularly by regulating fat metabolism, indicating its potential use as a phytotherapeutic agent in managing obesity. Conclusion: Administration of red ginger extract (Zingiber officinale var. rubrum) proved effective in reducing the body weight of obese mice, evidenced by a significant difference between body weight before and after treatment, with greater weight reduction observed in the treatment groups compared to the control group.
Co-Authors Abdul Mubdi Ardiansar Adriani Andi Alamanda Irwan Anna Sari Dewi Asrini Safitri Astra Budiati Nusrat Berry Erida Hasbi Dwi Anggita Faizul A Harry Nugraha Bachtiar Ida Royani Iin Widya Ningsi Indah Lestari Daeng Kanang Irmayanti Haidir Bima M. Hamsah Mohammad Reza Zainal Abidin Mufthiar Muhtar Muhammad Erlangga Dewantara djoharam Muhammad Fauzul Azhim Muhammad Irsan Muflih Mundzir Mustari, Ikhsanul Fauzi Nadila Ardyani Nahardi Nasrudin Andi Mappaware Nevi sulvita karsa Nurfadhillah Khalid Prema Hapsari Hidayati Rizky Nurhumairah Sarifuddin Sidrah Darma Sigit Dwi Pramono Sri Julyani Waode Inayatu Zahra Khairunnufus Wawan Susilo Wulan Purnamasyani S Zulfikri Khalil Novriansyah