Article Per Year (5 Year)
p-Index From 2021 - 2026
0.562
P-Index
This Author published in this journals
All Journal PREPOTIF : Jurnal Kesehatan Masyarakat JOURNAL LA MEDIHEALTICO Majalah Anestesia & Critical Care (MACC)
Sidemen, IGP Sukrana
Unknown Affiliation
Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : JOURNAL LA MEDIHEALTICO

 1 
Comparison of Inflammation, Pain, and Recovery in Colorectal Cancer Patients Undergoing Surgery with General Anesthesia and Combined Epidural Kenzi, Ignatio Armando; Hartawan, IGAG Utara; Sidemen, IGP Sukrana; Agung Senapathi, Tjokorda Gde; Gede Widnyana, I Made
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.2002

Abstract

Colorectal cancer has a high incidence and mortality rate. Surgery can increase the cytokine IL-6 which triggers inflammation and metastasis. The combination of general and epidural anesthesia has the potential to suppress IL-6, improve the tumor microenvironment, provide analgesia and improve postoperative recovery. To compare the effectiveness of postoperative analgesia quality in colorectal cancer patients receiving general anesthesia with combined epidural anesthesia. The single blind RCT study involved 44 patients who underwent surgery on colorectal cancer at Prof. Ngoerah Hospital. The study subjects were divided into two groups, group K who received general anesthesia and group P who received general anesthesia combined with epidural anesthesia. Patients' IL-6 will be evaluated preoperatively and 6 hours postoperatively. VAS and QOR-15 will be assessed 24 hours postoperatively. Of the 44 patients analyzed, the combined general anesthesia with epidural anesthesia group showed a significantly lower difference in IL-6 levels compared to the general anesthesia alone group of -14.69 [95% CI, p = <0.001]. The 24-hour postoperative VAS score was significantly lower than conventional general anesthesia, both in stationary and mobile conditions. In postoperative recovery, it was found that conventional general anesthesia combined with epdiural anesthesia gave greater QOR-15 results compared to conventional general anesthesia. General anesthesia combined with epidural anesthesia in colorectal cancer patients undergoing surgery can provide a lower difference in IL-6, lower VAS and higher QOR-15 postoperative satisfaction than the general anesthesia group.
Co-Authors Aryasa EM, Tjahya Dewi, I Dewa Ayu Mas Shintya Hartawan, IGAG Utara I Made Gede Widnyana I Made Prema Putra Jeanne, Bianca Kadek Agus Heryana Putra, Kadek Agus Kenzi, Ignatio Armando Kurniyanta, I Putu Putu Pramana Suarjaya Suastika, I Gede Juli Tjokorda Gde Agung Senapathi Tjokorda Gde Bagus Mahadewa