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All Journal Kappa Journal Media for Empowerment, Mobilization, and Innovation in Research & Community Indonesian Journal of Innovation in Education Research
Syahrial A
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Astronomy Education Energy Languange, Linguistic, Communication & Media Mathematics Physics Social Sciences Other

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The Influence of Skin Permeability and Electric Fields on Drug Permeation in Transdermal Systems: A Simulation-Based Study Using Pascal Taufik, Muhammad; Syahrial A
Kappa Journal Vol 8 No 3 (2024): Desember
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/kpj.v8i3.28845

Abstract

Transdermal drug delivery systems (TDDS) offer a promising non-invasive approach for drug administration, yet their effectiveness is often constrained by the permeability of the skin and the properties of the drug. This study investigates the combined impact of skin permeability and electric fields on drug permeation through the skin, using simulation data generated by a custom-developed program in Pascal. The simulation, based on Fick’s Law of Diffusion, incorporates the effects of iontophoresis (electric fields) on drug transport, adjusting parameters such as skin permeability, electric field strength, and drug characteristics. The results demonstrate that both skin permeability and electric field intensity significantly influence the rate of drug permeation. Notably, the highest flux was observed when both electric field strength (1.0 mA/cm²) and enhanced skin permeability (3.5 coefficient) were applied, with drug flux increasing by up to 5 times compared to passive diffusion. These findings underscore the substantial benefits of combining skin permeability enhancers, such as microneedles or chemical enhancers, with electric field application, offering valuable insights for developing more efficient TDDS. The results suggest that optimizing both parameters can significantly improve drug delivery, especially for low-permeability drugs.
Implementation of the GASING Method in Teaching Parabolic Motion: A Comparative Analysis of Learning Outcomes in Biology Education Taufik, Muhammad; Syahrial A
Kappa Journal Vol 8 No 3 (2024): Desember
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/kpj.v8i3.28890

Abstract

Teaching of physics concepts to non-physics majors presents significant challenges, particularly when it comes to helping students connect abstract physical principles with their primary field of study. This study investigates the effectiveness of the GASING (Graduated Assistance in Student-led Inquiry and Narrative learning through Guided experimentation) method in teaching parabolic motion to first-semester Biology Education students FKIP Universitas Mataram. Using a quasi-experimental design with two parallel classes (n = 54), we assessed the method’s effectiveness through pre- and post-tests, mini-projects, laboratory observations, and detailed student feedback questionnaires. Results demonstrated significant improvements in conceptual understanding, with mean scores increasing from 4.15 to 7.63 (Class D) and 7.56 (Class E), yielding a substantial effect size (Cohen’s d = 3.26). Both classes showed comparable performance in mini-projects (mean scores: 16.0/20 and 16.3/20). Student feedback across multiple engagement, clarity, and effectiveness measures consistently scored above 4.0/5. Statistical analysis revealed a significant correlation between student engagement and learning outcomes (r = 0.78, p < 0.001). These findings suggest that the GASING method effectively bridges the gap between physics concepts and biological applications while maintaining high student engagement and comprehension
Developing Students' Potential Skills Through the Implementation of Educational Activities Outside the School Environment in the Post-Pandemic Era Yunitun Tamara; Syahrial A; Muhammad Zuhdi; Dian Wijaya Kurniawidi; Syamsuddin, Syamsuddin; Kormil Saputra; Rahmatun Inayah; Ika Umratul Asni Aminy; Adella Ulyandana Jayatri
Media for Empowerment, Mobilization, and Innovation in Research & Community Vol. 1 No. 1 (2025): January-June
Publisher : Future Tecno-Science Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59535/c5x64z03

Abstract

Community service in Narmada Village, West Lombok, aimed to improve the quality of science and technology literacy learning through a contextual and educational approach. These activities included teaching practices using simple teaching aids, training in developing locally-based Lesson Plans (RPPs), and digital image security education using the SCBIE encryption algorithm. Results showed significant improvements in students' understanding of science concepts and active participation, as well as teachers' skills in designing relevant RPPs. Furthermore, an understanding of the effectiveness of the SCBIE algorithm was gained, with the use of a single key yielding higher e-RMS values, indicating a stronger encryption level. A comparison of the performance of algorithms A and B was also discussed during the training, emphasizing the importance of balancing speed, accuracy, and memory efficiency in implementing image cryptography. This activity significantly contributed to improving educational capacity and digital literacy at the village level.
Answering Multidimensional Challenges Through the Implementation of the 2013 Curriculum: Characteristics of Character Education Syahidi, Khaerus; Muhammad Sarjan; Joni Rokhmat; Syahrial A; I Gde Mertha; Kurniawan Arizona; Syamsuddin; Ramdhani Sucilestari
Indonesian Journal of Innovation in Education Research Vol. 1 No. 1 (2025): January
Publisher : Yayasan Arfah Bin Haji Muhammad Saleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63980/ijier.v1i1.1

Abstract

The implementation of character education in formal education environments has an effective influence in overcoming the phenomena of anarchism, imposition of will, student fights, proliferation of drug dealers and users, environmental crises, moral crises, and various other social tendencies. Formal education is an organized, directed, and measurable education system. The 2013 Curriculum orients and emphasizes the Strengthening of moral, affective, and conceptual values ​​​​of KI-1 (spiritual attitudes), KI-2 (social attitudes), KI-3 (knowledge), and KI-4 (application of knowledge). The implementation of character education in the 2013 Curriculum can be developed by integrating cognitive, affective, and psychomotor aspects. In addition, to encourage and facilitate the realization of Synergy between formal, non-formal and informal education, and encourage to Continue to improve the competence and role models of educators to implement the 2013 Curriculum
Co-Authors Adella Ulyandana Jayatri Dian Wijaya Kurniawidi I Gde Mertha Ika Umratul Asni Aminy Joni Rokhmat Khaerus Syahidi Kormil Saputra Kurniawan Arizona Muhammad Sarjan MUHAMMAD TAUFIK Muhammad Zuhdi Rahmatun Inayah Ramdhani Sucilestari Syamsuddin Syamsuddin Syamsuddin Yunitun Tamara