Claim Missing Document
Check
Articles

Found 14 Documents
Search

Formulasi dan Evaluasi Liposom Krim Ekstrak Daun Ubi Jalar Ungu (Lpomoea Batatas L.) Sugindro Sugindro; Asri Anjeliani; Dedy Ma'ruf; Taufiq Dalming; Alamsyah Alamsyah
Jurnal Kesehatan Amanah Vol. 9 No. 2 (2025): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v9i2.994

Abstract

Liposomes are good carriers that can be used to reduce toxic effects, increase drug effectiveness, increase the solubility of materials and permeability penetration of the compounds they carry, liposomes can also have potential as a system for controlling and targeting drug delivery. The aim of this research was to design a liposomal cream formula from purple sweet potato leaf extract (Ipomoea batatas L.) and to determine the quality of a liposomal cream preparation from purple sweet potato leaf extract (LPomoea batatas L.). The method used in this research uses a laboratory experimental method which aims to produce a liposomal cream preparation of purple sweet potato leaf extract (Ipomoea batatas L.).   Liposome preparations were made with a concentration of 1% purple sweet potato leaf extract, the results obtained were ball-shaped liposomes and some were oval-shaped, then the liposomes were used as an active substance to make cream with concentrations of 1%, 3% and 5%, then the liposomal cream formula was tested organoleptic, pH test, homogeneity test, spreadability test, adhesion test and stability test. The results of the stability test show that in F0, F1, F2 and F3 after storage at temperatures of 2°C and 35°C there was no change in the test. organoleptic, homogeneity test and pH test which means that the preparation is able to survive within the specified limits. However, in the test the spreading power of F0, F1, F2, and F3 experienced changes which meant that the preparation was not able to survive with a spreading power that remained within the specified limits.
Formulation And Physical Stability Testing Of Emulgel Preparation Of Rainbow Leaf Extract (Eucalyptus Deglupta Blume) With Combination Of Carbopol 940 And Hpmc Gelling Agent Concentrations Siti Saharah Abdullah; Taufiq Dalming; Ferawati Fajrin Abidin
Proceeding of the International Conference on Health Sciences and Nursing Vol. 2 No. 1 (2025): Proceeding of the International Conference on Health Sciences and Nursing
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ichsn.v2i1.60

Abstract

Rainbow leaves are known to have antibacterial and anti-inflammatory activities, so they have the potential to be developed in the form of practical and comfortable topical emulgel preparations. This study aims to formulate and evaluate the physical stability of rainbow leaf extract emulgel preparations (Eucalyptus deglupta Blume) with variations in the combination of gelling agent concentrations Carbopol 940 and HPMC. Three emulgel formulas were made with different concentrations of Carbopol 940 and HPMC, then evaluated through organoleptic tests, homogeneity, pH, spreadability, adhesion, viscosity, and physical stability tests using the freeze-thaw method for 6 cycles. The evaluation results showed that all formulas met good physical parameters, with formula F1 (Carbopol 940 0.5% and HPMC 1.5%) showing the most optimal results in terms of viscosity, spreadability, and adhesion. Thus, the combination of Carbopol 940 and HPMC at optimal concentration can produce a physically stable rainbow leaf extract emulgel preparation that is suitable for topical application.
Potensi Serat Lobak Putih (Raphanus sativus L.) sebagai Agen Penurun Kolesterol: Studi In Vitro Menggunakan UV-Vis Taufiq Dalming; Gesi Gusti
Jurnal Manajemen Bisnis dan Kesehatan Vol. 2 No. 2 (2025): Vol.2 No.2 2025 October-Desember
Publisher : Edu Berjaya Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70817/jmbk.v2i2.56

Abstract

Hiperkolesterolemia merupakan faktor risiko utama penyakit kardiovaskular yang menjadi penyebab kematian tertinggi di dunia. Pendekatan non-farmakologis berbasis serat pangan menjadi strategi alternatif yang menjanjikan untuk penatalaksanaan hiperkolesterolemia. Penelitian ini bertujuan untuk mengevaluasi kapasitas pengikatan kolesterol oleh serat lobak putih (Raphanus sativus L.) secara in vitro menggunakan spektrofotometri UV-Vis. Serat lobak putih dipersiapkan melalui proses hidrolisis dengan H₂SO₄ dan NaOH, kemudian diuji dengan larutan kolesterol 200 ppm yang telah direaksikan dengan reagen FeCl₃. Pengujian dilakukan dengan tiga variasi konsentrasi serat (0,1 g, 0,2 g, dan 0,3 g) dan tiga interval waktu inkubasi (60, 120, dan 180 menit). Absorbansi diukur menggunakan spektrofotometer UV-Vis pada panjang gelombang 450 nm. Hasil penelitian menunjukkan bahwa serat lobak putih mampu menurunkan konsentrasi kolesterol dengan persentase penurunan tertinggi sebesar 7,2% pada konsentrasi serat 0,3 g dengan waktu inkubasi 15 menit, dan 20,2% pada konsentrasi serat 0,3 g dengan waktu inkubasi 180 menit. Kapasitas pengikatan kolesterol meningkat secara konsisten seiring dengan peningkatan konsentrasi serat dan durasi inkubasi. Data kurva kalibrasi menunjukkan hubungan linear yang sangat baik (R² = 0,9943). Kesimpulannya, serat lobak putih memiliki potensi nyata sebagai agen penurun kolesterol melalui mekanisme pengikatan asam empedu. Temuan ini memberikan dasar ilmiah untuk pengembangan lobak putih sebagai pangan fungsional dalam pencegahan dan penatalaksanaan hiperkolesterolemia, meskipun penelitian in vivo dan uji klinis masih diperlukan untuk mengonfirmasi efektivitas biologis.
The Role of Kodam XIV / Hasanuddin Health Team in Natural Disaster Management Luther Loginsi; Andi Yusuf; Rahmawati Azis; Taufiq Dalming
Jurnal Ilmiah Kesehatan Sandi Husada Vol. 12 No. 2 (2023): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : LPPM Politeknik Sandi Karsa, South Sulawesi, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiksh.v12i2.497

Abstract

The role of the Kodam XIV / Hasanuddin and TNI health teams in natural disaster management is essential to provide health services and prevent more casualties. However, a deeper understanding of the effectiveness and challenges faced is needed. This study aims to analyze the role of Kodam XIV / Hasanuddin Health in natural disaster management, focusing on mitigation governance, early warning, and disaster preparedness. This research uses qualitative descriptive methods to describe what is happening in the field in related agencies. Data is collected through observation, interviews, and documentation by applying source, data, and time triangulation to ensure the validity and credibility of the information obtained. This research was conducted in West Sulawesi, a province prone to floods, tsunamis, earthquakes, etc. The Health Team of Kodam XIV / Hasanuddin plays an active role in disaster risk management by carrying out mitigation in the form of wave containment infrastructure development and normalization, as well as conducting early warning through the installation of EWS tools controlled by BPBD and BMKG, and conducting training, socialization, and preparing disaster risk reduction plans in the preparedness cycle. It was concluded that the health team of Kodam XIV/Hasanuddin has a central role in disaster risk management by implementing various programs such as mitigation, early warning, and preparedness, as well as providing education and training to the community to increase awareness and response to disasters.