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Tingkat Pengetahuan Dan Perilaku Swamedikasi Penggunaan Obat Bebas Pada Masyarakat Di Kecamatan Simpang Kanan Kabupaten Rokan Hilir Ayu Rahmawati; Nursyafni; Novtafia Endri; Muhammad Arif; Nawwar Irfan; Wulandari, Tri Ayu; Fitratul Wahyuni
The Journal Of Pharmacy Vol. 2 No. 1 (2024): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Self-medication is an act of self-medication carried out by the community to maintain health or manage disease based on personal diagnosis, using drugs repeatedly. This study aims to analyze the relationship between knowledge level and self-medication behavior using over-the-counter drugs in the community in Simpang Kanan District, Rokan Hilir Regency. The research was conducted observational with a cross-sectional approach, using quota sampling technique and questionnaires as instruments. The results showed that out of 90 respondents, 77.8% had good knowledge, 21.1% had sufficient knowledge, and 1.1% had poor knowledge. In terms of behavior, 81.1% had good behavior, while 18.9% had moderate behavior in self-medication. Analysis using the Chi-Square test resulted in a p-value of 0.002 (p<0.05), indicating a significant relationship between the level of knowledge and behavior of self-medication using over-the-counter drugs in the community in Simpang Kanan District, Rokan Hilir Regency.
Hubungan Pengetahuan Dengan Perilaku Dan Rasionalitas Penggunaan Parasetamol Sebagai Upaya Swamedikasi Di Kalangan Ibu Rumah Tangga Najmi Hilaliyati; Izza Aulia Rizqika Nasution; Reza Laila Najmi; Efilia Meirita; Fitratul wahyuni; Fitria Anggraini
The Journal Of Pharmacy Vol. 2 No. 2 (2025): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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The use of over-the-counter drugs such as paracetamol in self-medication is commonly practiced by the public, particularly among housewives. This study aims to determine the correlation between the level of knowledge and the behavior and rationality of paracetamol use in self-medication among housewives in Nagari Sungai Pua. The research employed an observational design with a cross-sectional approach. Samples were selected using purposive sampling, and data were collected through a structured questionnaire. The results showed that the majority of housewives had a good level of knowledge (77.3%), demonstrated positive behavior (63.9%), and used paracetamol rationally (86.6%). Spearman correlation analysis indicated a significant relationship between knowledge and behavior (p < 0.05), as well as between knowledge and the rationality of paracetamol use (p < 0.05). The study concludes that there is a significant correlation between the level of knowledge of housewives and their behavior and rational use of paracetamol in self-medication. It is recommended to enhance public education regarding rational drug use through health professional counseling.
Efektivitas Antibakteri Ekstrak Etanol Kulit Jeruk Manis (Citrus sinensis (L).) Terhadap Pertumbuhan Bakteri Penyebab Jerawat Staphylococcus epidermidis Fitratul wahyuni; Dhea Frediriva Anuar; Nawwar Irfan; Efilia Meirita; Reza Laila Najmi; Najmi Hilaliyati; Izza Aulia Rizqika Nasution
The Journal Of Pharmacy Vol. 3 No. 2 (2026): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Acne (Acne vulgaris) is a skin condition frequently caused by the bacterium Staphylococcus epidermidis. Sweet orange peel (Citrus sinensis (L.)) is an agricultural waste product with potential as a natural antibacterial agent due to its content of various secondary metabolites. This study aimed to determine the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), and antibacterial activity of the ethanolic extract of sweet orange peel against the growth of Staphylococcus epidermidis. The study employed the maceration method using 70% ethanol as the solvent. Standardization was conducted through specific and non-specific parameter tests. The MIC was determined using the broth dilution method with a UV-Vis spectrophotometer at concentrations of 6%, 7%, 8%, and 9%, while the MBC was determined using the subculture method on Nutrient Agar medium. Antibacterial activity was assessed using the disc diffusion method at concentrations of 10%, 20%, and 30%. The results showed that the crude drug material (simplicia) and the extract tested positive for alkaloids, flavonoids, saponins, tannins, and terpenoids. Values ​​for loss on drying and total ash content met quality requirements (<10%). Both MIC and MBC values ​​were observed at a concentration of 9%. The average inhibition zone diameters at concentrations of 10%, 20%, and 30% were 10.01 mm, 13.96 mm, and 18.06 mm, respectively, indicating strong inhibitory activity. It is concluded that the ethanolic extract of sweet orange peel (Citrus sinensis (L.)) possesses strong antibacterial activity against Staphylococcus epidermidis and has the potential to be developed as a natural agent for acne treatment.