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Journal : Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran

Efektifitas Ekstrak Daun Kesemek Hitam (Diospyros Nigra) Sebagai Alternatif Penurunan Kadar Glukosa Tikus Putih (Rattus Norvegicus) Haryanto Haryanto; Suci Aulia Rahmadani; Rana Muthia Najwa; Afandi Afandi
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 3 No. 2 (2025): Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v3i2.4912

Abstract

Plants contain several active ingredients beneficial for health, one of which is the persimmon plant, known for its tannins and phenolic compounds. This research aims to determine the effect of Black Persimmon Leaf Extract (Diospyros nigra) as an alternative for lowering glucose levels in White Rats (Rattus norvegicus). This is a True Experimental research, which controls all external variables that could affect the experimental results. There are four control groups: a negative control using glucose and positive controls using extracts with concentrations of 15%, 30%, and 60%. The research data were measured using a UV-Vis Spectrophotometer and analyzed using One Way ANOVA with SPSS. The results of the Shapiro-Wilk normality test showed a significance value >0.05; Levene's Test for homogeneity showed a significance value >0.05; the One Way ANOVA test showed a significance value <0.05; and the Tukey HSD test showed a significance value >0.05. The objective of this research is to test the effectiveness of black persimmon leaves (Diospyros nigra) as an alternative to lowering blood glucose levels in white rats (Rattus norvegicus). Sample absorbance data were obtained using UV-VIS Spectrophotometry and analyzed using One Way ANOVA in SPSS.
Uji Efektivitas Daun Bungur (Lagerstroemia speciosa L.) terhadap Penghambatan Transportasi Glukosa Tikus Putih Galur Wistar (Rattus norvegicus) Haryanto Haryanto; Muhammad Halim Ramadhan; Rifdah Rifdah; Dian Indra Aulia; Harianti Harianti; Nadia Azzahra
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 3 No. 2 (2025): Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v3i2.4913

Abstract

This study investigated the effects of bungur leaves containing saponins, flavonoids and tannins on glucose and cholesterol levels in rat (Rattus norvegicus) test animals. Spectrophotometry results showed a significant decrease in glucose levels at different concentrations. SPSS analysis indicated that the data were normally distributed, and comparison of average glucose levels between treatment groups showed similar homogeneity. The significant value of bungur obtained was 0.014 < 0.05 from the ANOVA test, strengthening the conclusion that bungur leaves can contribute to glucose control which aims to increase the potential of active compounds contained in bungur samples in inhibiting blood glucose absorption.