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All Journal Journal of Social Research Surabaya Biomedical Journal
Asami Rietta Kumala
Universitas Hang Tuah
Humanities Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Nursing Social Sciences

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Characteristics of Ischemic Stroke Patients With COVID-19 Based on Gender and Age at RSPAL Dr. Ramelan Surabaya From 2020 To 2022 Loula Kamal; Ni Komang Sri Dewi Untari; Duti Sriwati Aziz; Asami Rietta Kumala
Journal of Social Research Vol. 5 No. 3 (2026): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v5i3.3046

Abstract

Stroke is the second leading cause of death worldwide. Most strokes are ischemic, with varying incidence by age and gender. COVID-19 is known to increase the risk of acute ischemic stroke through inflammatory and hypercoagulable mechanisms. According to the WHO, COVID-19 patients have an estimated 5% risk of developing ischemic stroke. Previous research indicates that ischemic stroke associated with COVID-19 predominantly occurs in patients over 69 years of age and is more common in men. This study aimed to determine the characteristics of ischemic stroke patients associated with COVID-19 based on gender and age at Dr. Ramelan Naval Hospital, Surabaya, from 2020 to 2022. This descriptive study employed quantitative methods using secondary data derived from the medical records of patients who met the inclusion criteria. The study was conducted at Dr. Ramelan Naval Hospital, Surabaya, from March to September 2025. The results showed that, of the 86 cases, 90.7% of patients were identified as having risk factors for cardiovascular disease. Among patients with risk factors, males were more numerous (69%), with a predominance in the ?50-year age group (88%). However, among patients without risk factors, the numbers of males and females were relatively equal, with a similar predominance in the ?50-year age group (75%). The conclusion of this study is that ischemic stroke patients with COVID-19 at Dr. Ramelan Naval Hospital, Surabaya, between 2020 and 2022 were predominantly male and aged ?50 years.
Patin sebagai sumber omega 3 untuk menurunkan faktor resiko terjadinya MAFLD karena DM tipe 2 Indri N. Rahayu; Asami Rietta Kumala; Dody Taruna; Stefanus Djoni Husodo; Eric Mayo Dagradi; Judya Sukmana
Surabaya Biomedical Journal Vol. 3 No. 1 (2023): September
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v3i1.114

Abstract

Diet asam lemak tak jenuh ganda (PUFA) telah diteliti dan terbukti dapat memodulasi peradangan, namun, hanya sedikit beberapa penelitian yang fokusnya pada patobiologi PUFA dengan menggunakan diet isokalori dan isolipid namun belum dapat dijelaskan apakah patologi terkait tersebut disebabkan oleh komposisi diet PUFA, metabolisme lipid, atau obesitas, karena sebagian besar penelitian membandingkan diet dengan yang diberi makan ad libitum. Stres oksidatif dan mitokondria hati berperan dalam patogenesis penyakit hati berlemak nonalcohol. Omega-3 PUFA memiliki peran protektif yang potensial terhadap kerusakan sel oksidatif yang diinduksi ROS pada tikus organ, terutama di hati. Atenuasi hepatic fibrosis oleh EPA (asam eicosapentaenoic) secara signifikan berhubungan dengan kadar ROS hati. EPA juga menekan peningkatan kadar ROS hati dan penurunan penanda oksidatif serum, seperti 8-isoprostan dan feritin. Ikan patin memiliki kandungan asam lemak tak jenuh ganda omega 3 serta selenium yang merupakan antioksidan sehingga dapat menghambat terjadinya progresifisitas kejadian NAFLD maupun MAFLD. Mekanismenya antara lain melalui jalur penghambatan stress oksidatif yang merupakan patofisiologi terjadinya NAFLD maupun MAFLD.
Co-Authors Dody Taruna Duti Sriwati Aziz Eric Mayo Dagradi Indri N. Rahayu Judya Sukmana Loula Kamal Ni Komang Sri Dewi Untari Stefanus Djoni Husodo