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All Journal Indonesian Journal of Global Health research Indonesian Journal of Global Health Research
Rini Savitri Daulay
Universitas Sumatera Utara
Education Health Professions Languange, Linguistic, Communication & Media Nursing Public Health

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Relationship between Age and the Occurrence of Depression Symptoms in Children with Acute Lymphoblastic Leukemia Dwika Intania Riano; Ika Citra Dewi Tanjung; Ririe Fachrina Malisie; Arlinda Sari Wahyuni; Olga Rasiyanti Siregar; Rini Savitri Daulay
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.6230

Abstract

In children and adolescents, depressive symptoms often presenting as irritability, anhedonia, or behavioral changes. Despite significant advancements in survival rates due to improved therapeutic protocols, the psychological burden experienced by children with ALL.Objective: To evaluate the relationship between age and the presence of depressive symptoms in children diagnosed with ALL.Methods: A cross-sectional study was done using consecutive sampling with 40 children aged from 7 to 18 years old acquired, conducted from August to October 2024 at the outpatient unit of Adam Malik Hospital, Medan. Forty children aged 7–18 years with a confirmed diagnosis of ALL were included. Depressive symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9). Categorical variables were analyzed using the chi-square test, followed by bivariate to identify significant predictors of depression.Results: Among the 40 participants, the most age group were children ≤ 10 years old (65%). A statistically significant association was found between age group and the presence of depressive symptoms (p = 0.001, OR= 33,3). Conclusions: Age is significantly associated with the severity and presence of depressive symptoms in pediatric patients with ALL. Older children were more likely to report higher levels of depression. Psychological evaluation and targeted mental health support may be especially important in older age groups.
Correlation between Procalcitonin Values and Pneumonia Severity in Pediatric Patients Yogi Zulkifli; Rini Savitri Daulay; Fera Wahyuni; Ranti Permatasari; Hendri Wijaya; Fathia Meirina
Indonesian Journal of Global Health Research Vol. 8 No. 1 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i1.237

Abstract

Pneumonia remains one of the leading causes of morbidity and mortality among children, particularly in developing countries. Rapid assessment of disease severity is essential for appropriate clinical management. Procalcitonin (PCT) is recognized as a biomarker of systemic bacterial infection; however, its role in determining the severity of pediatric pneumonia is still debated. This study aimed to analyze the correlation between procalcitonin levels and pneumonia severity in pediatric patient. This was an observational analytic study with a retrospective cross-sectional design using consecutive sampling. Data were collected from medical records of 102 pediatric patients aged 1 month to 18 years who were diagnosed with pneumonia throughout 2024. PCT levels were compared between children with severe pneumonia and those with severe pneumonia accompanied by danger signs. Statistical analysis included the Mann-Whitney test to assess differences in PCT values and ROC curve analysis to determine the optimal cut-off, sensitivity, specificity, and accuracy. The majority of patients (71.6%) presented with severe pneumonia with danger signs. PCT levels differed significantly between groups (p < 0.001). ROC analysis identified an optimal cut-off value of ≥1.06 µg/L, yielding a sensitivity of 82.2%, specificity of 79.3%, positive predictive value of 90.9%, negative predictive value of 63.9%, and overall accuracy of 81.37% (AUC = 0.874). There is a significant association between procalcitonin levels and the severity of pneumonia in children. Procalcitonin may serve as a valuable early biomarker for assessing disease severity and guiding clinical decision-making in pediatric pneumonia, particularly in healthcare settings in North Sumatra.
Co-Authors Arlinda Sari Wahyuni Dwika Intania Riano Fathia Meirina Fera Wahyuni Hendri Wijaya Ika Citra Dewi Tanjung Olga Rasiyanti Siregar Ranti Permatasari Ririe Fachrina Malisie Yogi Zulkifli