Garuda - Garba Rujukan Digital

Pengaruh Ekstrak Daun Sirsak (Annona Muricata L.) terhadap Fungsi Ginjal dan Histopatologi Tikus Putih Wistar Jantan Penderita Diabetes Melitus Usiana, Gusti Nyoman Bagus; Yumardika, Deza; Angkasa, Celvin
JURNAL PENELITIAN PENDIDIKAN, PSIKOLOGI DAN KESEHATAN (J-P3K) Vol 6, No 2 (2025): J-P3K
Publisher : Yayasan Mata Pena Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51849/j-p3k.v6i2.758

Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak daun sirsak (Annona muricata L.) terhadap fungsi ginjal dan gambaran histopatologi ginjal pada tikus putih jantan galur Wistar yang menderita diabetes melitus. Induksi diabetes melitus dilakukan dengan pemberian aloksan dan tikus dibagi menjadi beberapa kelompok, yaitu kelompok kontrol, kelompok diabetes, dan kelompok perlakuan yang diberi ekstrak daun sirsak dengan dosis yang berbeda-beda. Fungsi ginjal dinilai melalui kadar nitrogen urea darah (BUN), kreatinin serum, dan asam urat. Pemeriksaan histopatologi ginjal dilakukan dengan pewarnaan hematoksilin dan eosin. Hasil penelitian menunjukkan bahwa pemberian ekstrak daun sirsak secara signifikan memperbaiki fungsi ginjal dengan menurunkan kadar BUN, kreatinin serum, dan asam urat. Selain itu, analisis histopatologi menunjukkan adanya penurunan kerusakan jaringan ginjal akibat diabetes. Temuan ini menunjukkan bahwa ekstrak daun sirsak memiliki potensi efek terapeutik dalam memperbaiki fungsi ginjal dan mengurangi kerusakan ginjal pada tikus diabetes.

Factors influencing family planning acceptors' use of IUD contraception in the working area of Medan Amplas District Abdullah, Armelia Adel; Kaban, Lenni Apriani; Novianti, Desi; Hidayat, Andri; Ongko, Nicholas Xavier; Rosar, Naufal; Marpaung, Hans Hotma Haposan; Siregar, Lisdawaty; Sherliana, Ferra; Lizar, Budi Septhian; Angkasa, Celvin
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7437

Indonesia's high population growth rate is a big problem and needs serious handling from all parties of society and government The family planning movement is carried out to build a prosperous family in order to create optimal human resources. The family planning program is one of the most effective ways to improve family resilience, health, and safety of mothers, children, and women. Descriptive quantitative research, where this study aims to determine the factors that influence family planning acceptors on the use of IUD contraceptives in the Medan Amplas working area in 2024 using a cross-sectional design where the independent variable and the dependent variable are identified at the same time. The results of this study are There is an influence of education (P<0.05), mileage (P<0.05), knowledge (P<0.05), attitude (P,0.05), attitude (P<0.05), husband support (P<0.05), health worker support (P<0.05), The most dominant factor affecting the use of IUD contraceptives is the variable Husband support Exp (B) = 2.50 means that if there is husband's support for the use of IUD contraceptives then there are 2.5 times the mother wants to participate as an acceptor of IUD contraceptives. It is expected to Improve the Awareness Campaign Program by holding campaigns that target husbands and other family members, explaining the importance of their support in the use of contraceptives.

Factors influencing family planning acceptors' use of IUD contraception in the working area of Medan Amplas District Abdullah, Armelia Adel; Kaban, Lenni Apriani; Novianti, Desi; Hidayat, Andri; Ongko, Nicholas Xavier; Rosar, Naufal; Marpaung, Hans Hotma Haposan; Siregar, Lisdawaty; Sherliana, Ferra; Lizar, Budi Septhian; Angkasa, Celvin
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7437

Indonesia's high population growth rate is a big problem and needs serious handling from all parties of society and government The family planning movement is carried out to build a prosperous family in order to create optimal human resources. The family planning program is one of the most effective ways to improve family resilience, health, and safety of mothers, children, and women. Descriptive quantitative research, where this study aims to determine the factors that influence family planning acceptors on the use of IUD contraceptives in the Medan Amplas working area in 2024 using a cross-sectional design where the independent variable and the dependent variable are identified at the same time. The results of this study are There is an influence of education (P<0.05), mileage (P<0.05), knowledge (P<0.05), attitude (P,0.05), attitude (P<0.05), husband support (P<0.05), health worker support (P<0.05), The most dominant factor affecting the use of IUD contraceptives is the variable Husband support Exp (B) = 2.50 means that if there is husband's support for the use of IUD contraceptives then there are 2.5 times the mother wants to participate as an acceptor of IUD contraceptives. It is expected to Improve the Awareness Campaign Program by holding campaigns that target husbands and other family members, explaining the importance of their support in the use of contraceptives.

Risk factors for obesity and overweight in under-five children in a highland community, Kabanjahe Sibagariang, Eva Ellya; Ginting, Rapael; Sihombing, Rachel Raselia; Amir, Dwi Fenny; Meliala, Juli Elisabet Mayen Br; Angkasa, Celvin; Zubaidah, Siti; Sherliana, Ferra; Siregar, Hesti Despita
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 2 (2025): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i2.7746

Overnutrition in toddlers is a public health problem that continues to increase globally and nationally. In Indonesia, the prevalence of toddler obesity has risen from 10.5% (2007) to 21.8% (2018). In Karo Regency, the prevalence of toddler obesity reached 8.80%. Data from 2025 at Simpang Empat Community Health Center in Kabanjahe shows 12 toddlers with obesity and 49 toddlers with overnutrition. This study aims to analyze the relationship between maternal knowledge, attitudes, and practices with the occurrence of obesity and overnutrition in toddlers aged 12-60 months. The research method used an observational analytic design with a cross-sectional approach. The sample consisted of 61 toddlers with obesity or overnutrition, selected using total sampling. Data were collected through questionnaires and anthropometric measurements of BMI-for-age. Analysis used the Chi-Square test. Results show the majority of mothers had insufficient knowledge (57.4%), positive attitudes (63.9%), and suboptimal practices (65.6%). There was a significant relationship between knowledge (p=0.038), attitude (p=0.041), and practice (p=0.044) with the toddler's nutritional status. The study conclusion confirms that good nutritional care practices, supported by adequate knowledge and a positive attitude, play an important role in preventing obesity and overnutrition in toddlers.

Title

Found 4 Documents
Search

Abstract

Abstract

Abstract

Abstract

Title Search

Found 4 Documents Search

Abstract

Abstract

Abstract

Abstract

Title

Found 4 Documents
Search