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All Journal LEGAL BRIEF Asian Journal of Health Research Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Law and Economics
Muhammad Ali Sabisi
Universitas Batam
Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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HUBUNGAN ANTARA EKSPRESI CASPASE 3 DENGAN PROGRESIVITAS KANKER SERVIKS STADIUM IIA2 DAN IIB POST KEMOTERAPI NEOADJUVAN RSUP DR SARDJITO YOGYAKARTA Erika Kusumawardani; Muhammad Ali Sabisi
Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Vol 15 No 2 (2025): Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam
Publisher : Universitas Batam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37776/zked.v15i2.1817

Abstract

ABSTRAK LATAR BELAKANG: Kanker serviks merupakan salah satu kanker pada perempuan yang memiliki angka kejadian dan kematian yang tinggi di Indonesia. Pada kanker serviks stadium IIA2 dan IIB dikenal modalitas kemoterapi neoadjuvan sebelum operasi radikal yang bertujuan untuk mengurangi massa tumor sehingga memudahkan pembedahan dan menghambat mikrometastasis. Infeksi Human Papilloma Virus (HPV) merupakan faktor penting penyebab kanker serviks. Protein caspase 3 yang berperan dalam proses apoptosis berkaitan dengan patogenesis kanker serviks. Sampai saat ini, belum ada prediktor yang dapat digunakan untuk memprediksi progresivitas kanker serviks stadium IIA2 dan IIB setelah pemberian kemoterapi neoadjuvan. BACKGROUND: Cervical cancer is a cancer in women that has a high incidence and mortality in Indonesia. In stage IIA and IIB cervical cancer, neoadjuvant chemotherapy modality is known before radical surgery which aims to reduce tumor mass to facilitate surgery and inhibit micrometastatic. Human Papilloma Virus (HPV) infection is an important factor in causing cervical cancer. Caspase 3 protein which plays a role in the apoptosis process related to the pathogenesis of cervical cancer. Nowadays, there are no predictors that can be used to predict the progresivity of stage IIA2 and IIB cervical cancer after presenting neoadjuvant chemotherapy. Kata kunci: kanker, serviks, caspase 3, progresivitas, kemoterapi
Employment or Exploitation? A Legal Comparative Study of Domestic Worker Protection in Singapore and Indonesia Antony, Antony; Osmond, Agung Pratama; Ali Sabisi, Muhammad; Azlyn, Nurul; Rahmadani, Aini; Shahrullah, Rina Shahriyani
LEGAL BRIEF Vol. 14 No. 2 (2025): June: Law Science and Field
Publisher : IHSA Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/legal.v14i2.1313

Abstract

This study aims to analyze the comparative legal protection systems for Domestic Workers (DWs) in Indonesia and Singapore, while highlighting the urgency of ratifying ILO Convention No. 189 as an international instrument to ensure decent work in the domestic sector. The research employs an empirical legal method, utilizing statutory, conceptual, and empirical approaches. The statutory approach involves reviewing national and international regulations related to labor and domestic worker protection. The data consist of primary data from observations and interviews, as well as secondary data from primary legal sources such as the 1945 Constitution of the Republic of Indonesia, Law No. 13 of 2003, the Draft Bill on Domestic Workers, the Employment of Foreign Manpower Act (EFMA), the Employment Act, and international instruments such as ILO Convention No. 189. The data are analyzed using descriptive-qualitative methods with deductive reasoning to identify normative and empirical gaps in the protection of domestic workers. The findings reveal that both Indonesia and Singapore have yet to provide comprehensive legal protection for domestic workers, particularly regarding formal employment status, basic rights, and access to justice. The ratification of ILO Convention No. 189 is considered crucial for both countries to improve national legal frameworks, raise protection standards, and enhance their diplomatic position and international reputation in upholding human rights and social justice.
Ratifying the HCCH 2005 and 2019 Conventions: Legal Reform and the Pursuit of Certainty in Indonesia’s International Private Law Antony, Antony; Osmond, Agung Pratama; Sabisi, Muhammad Ali; Shahrullah, Rina Shahriyani
Law and Economics Vol. 19 No. 3 (2025): October: Law and Economics
Publisher : Institute for Law and Economics Studies

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/laweco.v19i3.219

Abstract

In the era of globalization, the increasing intensity of cross-border transactions demands a national legal system capable of ensuring legal certainty in international trade. However, Indonesia has yet to ratify the HCCH 2005 Convention on Choice of Court Agreements and the HCCH 2019 Convention on the Recognition and Enforcement of Foreign Judgments. This study aims to analyze the urgency of ratifying both conventions in the context of Indonesia’s international trade, assess the readiness of national legal and institutional frameworks, and examine lessons learned from countries that have ratified similar conventions. This research adopts a normative legal approach using three methods: the statutory approach to examine the relevance of national regulations, the conceptual approach to understand the foundational principles of the HCCH conventions, and the comparative approach through case studies of ratifying countries. The data sources consist of primary legal materials such as international conventions and national legislation, as well as secondary materials including scholarly journals and legal literature. The research question in this study is: 1) What is the urgency of ratifying the 2005 and 2019 HCCH Conventions in Indonesia?; 2) How prepared is Indonesia's legal and institutional system to accept the ratification of the 2005 and 2019 HCCH Conventions?; and 3) What lessons can Indonesia learn from countries that have ratified the 2005 and 2019 HCCH Conventions?. The findings reveal that, despite Indonesia's significant economic potential, its legal system has not yet adequately accommodated the recognition of jurisdiction and enforcement of foreign judgments. Countries such as Mexico, Singapore, and members of the European Union have demonstrated that ratifying these conventions strengthens legal certainty, enhances investor confidence, and expedites the resolution of cross-border disputes. This study concludes that the ratification of the HCCH 2005 and 2019 Conventions must be an integral part of Indonesia’s civil law reform agenda. The implication is that Indonesia must revise its national regulations, enhance institutional capacity, and develop a structured ratification roadmap to ensure effective implementation and reinforce its legal standing within the global system
The Imperforate Hymen: A Case Report on A Modern Hymenectomy Incision Method Erika Kusumawardani; M. Ali Sabisi; Adrian Desmar Pardomuan Ringo Ringo
Asian Journal of Health Research Vol. 5 No. 1 (2026): Volume 5 No 1 (April) 2026
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v5i1.322

Abstract

Introduction: An imperforate hymen is a congenital condition in which the hymen completely obstructs the vaginal canal. Many patients remain asymptomatic until menarche, when they may present with primary amenorrhea, a pelvic mass, and cyclic abdominal pain. The traditional hymenectomy technique involves a cruciate (cross-shaped) incision with excision of the quadrants and approximation of the hymenal edges to the vestibule using absorbable sutures. However, this method can be associated with scar formation and subsequent reclosure of the hymen. Case Presentation: A 12-year-old girl presented with cyclic abdominal pain for three months, which worsened one week prior to admission. She complained of severe abdominal pain starting six hours before hospital admission. Physical examination revealed a palpable lower abdominal mass, tenderness, and no visible hymenal opening. Ultrasonography showed hematometra and hematocolpos, leading to the diagnosis of imperforate hymen. The patient underwent an annular hymenectomy using electrocautery to create a circumferential (ring-shaped) excision, aiming to prevent postoperative hymenal closure and scarred hymenal contour. Conclusion: Imperforate hymen should be considered in premenarcheal adolescent girls presenting with cyclic abdominal pain. Annular hymenectomy using electrocautery offers a modern surgical approach that may reduce postoperative hymenal reclosure and scarring compared with the traditional cruciate technique.
HUBUNGAN TINGKAT STRESS AKADEMIK DAN KEJADIAN GASTROESOPHAGEAL REFLUX DISEASE (GERD) PADA MAHASISWA PROFESI DOKTER PROGRAM STUDI KEDOKTERAN, FAKULTAS KEDOKTERAN UNIVERSITAS BATAM Muhammad Ali Sabisi; Erika Kusumawardani
Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Vol 16 No 1 (2026): Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam
Publisher : Universitas Batam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37776/zked.v16i1.2094

Abstract

Introduction: Gastroesophageal reflux disease (GERD) is an upper gastrointestinal disorder caused by repeated reflux of gastric contents into the esophagus, leading to symptoms or complications. One of the risk factors for GERD is stress, which is commonly experienced by university students. This study aimed to determine the relationship between academic stress levels and the incidence of GERD among medical professional students of the Medical Study Program, Faculty of Medicine, Universitas Batam. Methods: This study employed a quantitative observational analytic design with a cross-sectional approach and utilized the Chi-square test. Total random sampling was applied based on inclusion and exclusion criteria. GERD was assessed using the GERD-Q questionnaire, while academic stress levels were measured using the Medical Student Stressor Questionnaire (MSSQ). Results: The results showed that a small proportion of students, 14.5% (9 students), experienced GERD symptoms. Nearly half of the respondents, 48.4% (30 students), experienced moderate stress, while 30.6% (13 students) experienced mild stress. A smaller proportion, 19.4% (12 students), experienced severe stress, and only 1.6% (1 student) experienced very severe stress. The Chi-square analysis revealed a p-value of 0.680 (p > 0.05) for the relationship between academic stress level and GERD incidence. Conclusion: There was no statistically significant relationship between academic stress level and the incidence of GERD among medical professional students. Keywords: Gastroesophageal reflux disease, GERD, GERD-Q, MSSQ, Academic stress
Co-Authors Adrian Desmar Pardomuan Ringo Ringo Azlyn, Nurul Erika Kusumawardani Erika Kusumawardani Osmond, Agung Pratama Rahmadani, Aini Rina Shahriyani Shahrullah Syamsiar, Syamsiar