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All Journal JP3 (Jurnal Pendidikan dan Profesi Pendidik) Jurnal Penelitian Pendidikan IPA (JPPIPA)
Nainggolan, Nadya
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Materials Science & Nanotechnology Physics

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UNDERSTANDING BY DESIGN: IDENTIFIKASI HASIL YANG DIINGINKAN DAN PENERAPANNYA DALAM PEMBELAJARAN MATEMATIKA Sabrina, Khoirunisa Aisha; Fitri, Magfira Annisa; Nainggolan, Nadya; Mulyatna, Fauzi
JP3 (Jurnal Pendidikan dan Profesi Pendidik) Vol 10, No 2 (2024): JP3 (Jurnal Pendidikan dan Profesi Pendidik)
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/jp3.v10i2.22743

Abstract

Penelitian ini bertujuan untuk mengetahui bagaimana identifikasi  hasil yang diinginkan pada pembelajaran matematika. Metode penelitian yang  digunakan adalah kualitatif dengan pendekatan kualitatif. Teknik pengumpulan  data dalam penelitian ini berupa tinjauan pustaka atau literature review. Hasil  penelitian menunjukkan bahwa penerapan Understanding by Design (UbD)  dalam pembelajaran matematika memiliki dampak positif dalam membantu  peserta didik memaknai materi yang diberikan, Dalam pengimplementasiannya,  guru dapat memberikan media pembelajaran yang inovatif untuk mendukung  keterlibatan peserta didik dan mengembangkan potensi yang telah dimilikinya. Media pembelajaran hendaknya disesuaikan dengan perkembangan zaman agar  peserta didik memiliki karakteristik abad 21 sebagai upaya menghadapi  tantangan global. Hal ini sejalan dengan pemikiran Ki Hadjar Dewantara sebagai  bapak pendidikan Indonesia mengenai kemerdekaan belajar serta kodrat alam  dan kodrat zaman. Materi yang diberikan hendaknya disesuaikan dengan  kebutuhan peserta didik agar dapat mengembangkan salah keterampilan abad  21 yakni critical thinking melalui pengalaman belajar yang bermakna, sehingga  peserta didik tidak hanya menghafal tetapi memahami konsep.
Effects of Stem Cell Therapy on Keloid Treatment: A Literature Review Eric, Eric; Angeline , Maria Olivia; Layrenshia, Belinda; Kelvin, Kelvin; Rianto, Louis; Nainggolan, Nadya; Willyana, Cindy; Radiance, Shamyra; Putri, Rizka Saffana Alinda
Jurnal Penelitian Pendidikan IPA Vol 10 No 6 (2024): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i6.3865

Abstract

Fibroblasts that produce excess collagen and growth factors play a role in the pathogenesis of keloid formation. In general, keloids are treated with intralesional corticosteroids alone or with a combination of other modalities, but the recurrence rate is still relatively high, so alternative treatments such as stem cells are being investigated, one of which is Mesenchymal Stem Cells (MSC), which have proven to be useful in healing keloids. Therefore, this literature review aims to discuss the effects of stem cell therapy in the treatment of keloids. In this literature review, 36 journals were used that discussed stem cell therapy in the treatment of keloids taken from various journal sources, namely Google Scholar, Pubmed, Medline, Ebsco, Hindawi, and Cochrane which were published within the last 10 years. According to the source, MSC is divided into 2 types, namely Adipose Mesenchymal Stem Cells (AMSC) and Bone Marrow Mesenchymal Stem Cells (BMMSC). In several studies, AMSC is known to reduce the expression of TGF-β1, COL-1, and COL-2 proteins, and has been shown to inhibit the proliferation of fibroblasts in keloid patients. Whereas in the BMMSC study that was applied with Hydroxybutyl chitosan (HBC) and Arg-Gly-Asp (RGD) hydrogels for 7 days, it was shown to significantly reduce nodular collagen fibers (p<0.05). Keloids occur due to excessive production of collagen and are influenced by various factors such as age, gender, skin color, and genetics. Stem cell therapy, such as MSC, has been proven in various studies to be an alternative treatment for keloids
Co-Authors Angeline , Maria Olivia Eric, Eric Fauzi Mulyatna Fitri, Magfira Annisa Kelvin Kelvin Layrenshia, Belinda Putri, Rizka Saffana Alinda Radiance, Shamyra Rianto, Louis Sabrina, Khoirunisa Aisha Willyana, Cindy