Article Per Year (5 Year)
p-Index From 2020 - 2025
0.408
P-Index
This Author published in this journals
All Journal Lantanida Journal JIPI (Jurnal IPA dan Pembelajaran IPA)
Fazli, Rahmad Rizki
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Physics

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
EKSTRAK GLUKOMANAN UMBI SUWEG (Amorphophallus campanulatus) ASAL PIDIE JAYA SEBAGAI BAHAN SEDIAAN MASKER ORGANIK YANG DIPERKAYA SERBUK DAUN KELOR Fazli, Rahmad Rizki; Hendriani, Rosa; Erlidawati, Erlidawati; Alvionita, Mieke
Lantanida Journal Vol 13 No 1 (2025): January-June 2025
Publisher : UIN AR-RANIRY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/lj.v13i1.28994

Abstract

The combination of D-mannose and D-glucose with β-1,4-glycosidic bonds with a ratio of 1.6:1 forms a straight chain polymer of glucomannan. Glucomannan flour is widely used in industry to make paper, adhesives, food ingredients, cosmetics, and cleaners. An organic mask preparation from glucomannan flour enriched with moringa leaf powder has been made from suweg tubers from Pidie Jaya, which is expected to be widely used, one of which is as a cosmetic ingredient. The purpose of this study was to determine the glucomannan content in suweg tubers from Pidie Jaya and to obtain the best formula of an organic mask based on panelist preferences. Glucomannan flour was extracted with 60% ethanol solvent and the glucomannan content test was carried out using the DNS method. The formulation of organic mask preparations includes glucomannan flour, moringa leaf powder, and H2O with different concentration ratios, namely F1 (50% glucomannan flour: 50% moringa leaf powder), F2 (75% glucomannan flour: 25% moringa leaf powder) and F3 (25% glucomannan flour: 75% moringa leaf powder). Then the physical properties were tested including pH test, homogeneity test, spreadability test, drying time test, and organoleptic test. The results of the study obtained a glucomannan content of 26.39%. The results of organoleptic testing showed that users preferred organic mask preparations from glucomannan flour enriched with moringa leaf powder formula F1 (50% glucomannan flour and 50% moringa leaf powder) both in terms of color, texture, odor/aroma, and general preference.
Experimental and Computational Studies on the Antiglaucoma Effects of Kelulut Honey (Heterotrigona itama) from Aceh in Rats (Rattus norvegicus) Erlidawati*, Erlidawati; Rizarullah, Rizarullah; Mustika, Chessy Rima; Awlanur, Cut; Fazli, Rahmad Rizki; Saaid, Mardiana
Jurnal IPA & Pembelajaran IPA Vol 9, No 2 (2025): JUNE 2025
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jipi.v9i2.45131

Abstract

This study aimed to evaluate the efficacy of kelulut (H. itama) honey as an antiglaucoma agent in rats. Kelulut honey diluted to a concentration of 400 ppm using distilled water was prepared for chemical and biological analysis. Secondary metabolites in the extracts were identified by phytochemical methods and antioxidant activity was evaluated by DPPH method. In vivo test was conducted on R. novergicus rats that had been treated with intraocular pressure with 5 treatment groups and 5 repetitions for the antiglaucoma test. In addition, in silico studies were also conducted using apigenin, cathecin, luteolin, naringenin and taxifolin against Rho Kinase protein. The results showed that kelulut honey extract has been confirmed to contain alkaloid, flavonoid, and flavone compound classes. The extract was also confirmed to have antioxidant activity with an IC50 value of 6.2 ppm against 5.4 ppm ascorbic acid. The findings showed that kelulut honey has efficacy as antiglaucoma in rats. The secondary metabolites in this honey, especially alkaloids, flavonoids, and flavones, showed high antioxidant activity (50). At a dose of 40 ppm, kelulut honey was showed to reduce intraocular pressure (IOP) by 46.56% in the right eye and 55.15% in the left eye of rats. This effect is comparable to the use of 2% pilocarpine. In silico study showed that all tested compounds have good binding affinity to protein targets, with promising key interactions. Therefore, kelulut honey was potentially a natural candidate for the development of antiglaucoma therapeutics.
Co-Authors Alvionita, Mieke Awlanur, Cut Erlidawati Erlidawati Erlidawati*, Erlidawati Hendriani, Rosa Mustika, Chessy Rima Rizarullah, Rizarullah Saaid, Mardiana