Article Per Year (5 Year)
p-Index From 2020 - 2025
0.408
P-Index
This Author published in this journals
All Journal Indonesian Journal of Global Health research The Journal of Society Medicine (JSOCMED)
Hutagalung, Patricia
Unknown Affiliation
Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Patch Test Analysis of Channa Striata Extract Biopolymer Dalimunthe, Dina A; Lubis, Flora Marita; Hazlianda, Cut Putri; Sinaga, Riana Miranda; Dhillon, Jesryn; Hutagalung, Patricia; Berlian, Guntur
Journal of Society Medicine Vol. 4 No. 6 (2025): June
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i6.217

Abstract

Introduction: Wound healing involves complex interactions between cells and mediators that occur immediately after the wound occurs and depends on nutritional factors and wound closure. Snakehead murrel fish (Channa striata) extract has been extensively researched to speed up the wound healing process because of its high amino acid content. Patch tests were carried out to assess the allergen potential of the Channa striata extract biopolymer in the form of wound dressings. Methods: Experimental study of 40 subjects who had admit patch test with various consentration of Channa striata extract biopolymer. The patch test materials divided of 5 grups. They were aquadest solution, Eucheuma cottonii biopolymer, Channa striata extract biopolymer concentrations of 5.4 g/mL, 10.8 g/mL, and 21.6 g/mL. All subjects had been assessed for skin reactions that occured after 48 hours, 72 hours, and 96 hours. Results: A total of 40 subjects met the inclusion criteria and completed informed consent.  There was minimum allergen reaction (+) in slight subject in all grups except aquadest grup after 48 hours. The allergic reaction dissolve in 72 and 96 hours. An irritant reaction (IR) occurred in among all grups but indicated to the  hypafix plaster. Conclusion: Patch test containing biopolymer Channa striata extract showed a minimal allergic reaction
Raynaud’s Phenomenon in A Patient with Scleroderma: A Case Report Hutagalung, Patricia; Nababan, Kristo Alberto
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6631

Abstract

Systemic sclerosis, or scleroderma, is a chronic autoimmune disorder characterized by fibrosis of the skin and internal organs, vasculopathy, and immune dysregulation. Raynaud’s phenomenon (RP), marked by episodic vasospasm of the digital arteries in response to cold exposure or emotional stress, is often one of the earliest and most common sign of SSc. Early diagnosis plays a crucial role in preventing and managing complications of RP, such as digital ulcers and tissue damage due to chronic circulatory impairment, as well as in reducing long-term disability. This case report aims to highlight pedal ulcers as a complication of RP scleroderma and to emphasize the importance of early intervention in preventing progressive tissue damage. The data was conducted through a comprehensive approach including history assessment, physical examinations, electronic medical record reviews, laboratory diagnostics, and imaging studies to ensure accurate diagnosis and effective interventions. We report a 26-year-old woman who presented with a six-month history of progressive skin thickening and hardening involving almost all of her body. The patient also experienced finger stiffness, flexion contractures, and limited mouth opening. Dermatological examination revealed sclerotic skin with hypopigmented and hyperpigmented patches forming a "salt-and-pepper" appearance across various body areas, along with microstomia and a beaked nose. The Modified Rodnan Skin Score (mRSS) was 34. A diagnosis of systemic sclerosis was established based on the American College of Rheumatology in collaboration with the European League Against Rheumatism (ACR/EULAR) criteria. The patient was lost to follow-up after the initial visit and later returned with toe necrosis and ulceration over the ankle area. Treatment included systemic corticosteroids combined with methotrexate, along with counseling to avoid cold exposure and manage stress. Raynaud’s phenomenon should be recognized as a critical early sign of scleroderma. Comprehensive early evaluation, including autoantibody testing, is essential for timely diagnosis and the prevention of severe vascular complications.
Co-Authors Berlian, Guntur Cut Putri Hazlianda Dalimunthe, Dina A Dhillon, Jesryn Lubis, Flora Marita Nababan, Kristo Alberto Sinaga, Riana Miranda