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All Journal Indonesian Journal of Global Health research The Journal of Society Medicine (JSOCMED) Journal of General Procedural Dermatology and Venereology Indonesia Cermin Dunia Kedokteran
Dhillon, Jesryn
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Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health

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Patch Test Analysis of Channa Striata Extract Biopolymer Dalimunthe, Dina A; Lubis, Flora Marita; Hazlianda, Cut Putri; Sinaga, Riana Miranda; Dhillon, Jesryn; Hutagalung, Patricia; Berlian, Guntur
Journal of Society Medicine Vol. 4 No. 6 (2025): June
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i6.217

Abstract

Introduction: Wound healing involves complex interactions between cells and mediators that occur immediately after the wound occurs and depends on nutritional factors and wound closure. Snakehead murrel fish (Channa striata) extract has been extensively researched to speed up the wound healing process because of its high amino acid content. Patch tests were carried out to assess the allergen potential of the Channa striata extract biopolymer in the form of wound dressings. Methods: Experimental study of 40 subjects who had admit patch test with various consentration of Channa striata extract biopolymer. The patch test materials divided of 5 grups. They were aquadest solution, Eucheuma cottonii biopolymer, Channa striata extract biopolymer concentrations of 5.4 g/mL, 10.8 g/mL, and 21.6 g/mL. All subjects had been assessed for skin reactions that occured after 48 hours, 72 hours, and 96 hours. Results: A total of 40 subjects met the inclusion criteria and completed informed consent.  There was minimum allergen reaction (+) in slight subject in all grups except aquadest grup after 48 hours. The allergic reaction dissolve in 72 and 96 hours. An irritant reaction (IR) occurred in among all grups but indicated to the  hypafix plaster. Conclusion: Patch test containing biopolymer Channa striata extract showed a minimal allergic reaction
Combination of Subcision, Microneedling, and Platelet-Rich Plasma Therapy in Patient with Grade Four Atrophic Acne Scars Dhillon, Jesryn; Nasution, Khairina; Jusuf, Nelva Karmila
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6682

Abstract

Atrophic acne scars affect up to 75% of patients with a history of acne and are often associated with significant psychosocial distress. These scars are classified into three main types: ice pick, rolling, and boxcar. A multimodal therapeutic approach is often required for effective management, particularly in severe cases. This report presents a case of a 40-year-old married woman with a 10-year history of inflammatory acne lesions that progressed into grade 4 atrophic scars. The acne was suspected to be triggered by injectable contraceptive use, which contains progestins with androgenic activity. The patient frequently picked at her acne, leading to deep scarring predominantly on both cheeks. Based on clinical evaluation, dermoscopy, and skin analyzer assessment, the patient underwent a series of treatments combining subcision, microneedling, and platelet-rich plasma (PRP) therapy. Following treatment, the Self-Assessment of Clinical Acne-Related Scars (SCARS) score improved from 22 to 14, while the Facial Acne Scar Quality of Life (FASQoL) score improved from 32 to 16. This case highlights the effectiveness of a combination approach in remodeling scar tissue and improving quality of life in patients with severe atrophic acne scars. A tailored, comprehensive treatment plan is essential for optimal outcomes.
Varicella Presentation in Adult: A Case Report Dhillon, Jesryn; Dalimunthe, Dina Arwina
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.7114

Abstract

Varicella is a disease caused by the varicella-zoster virus (VZV), a herpesvirus specific to humans. It is highly contagious but preventable through vaccination. It is usually diagnosed clinically and is often self-limiting. However, complications can include pneumonia, neurological, hematologic, ocular, renal, hepatic conditions, as well as sepsis, and secondary infections that can be fatal. Effective antiviral therapy has reduced associated morbidity and mortality. To report a case of varicella with bronchopneumonia in an adult patient. A 58-year-old male presented with persistent vesicular eruptions on the face, chest, back, and extremities. He was admitted to the emergency room and referred to dermatology. He had no history of prior varicella or vaccination. He was diagnosed with varicella with pneumonia and treated with acyclovir, cetirizine, paracetamol, and fusidic acid cream. Data were obtained through anamnesis, physical examination, and relevant supporting investigations, then qualitatively analyzed by correlating clinical findings and investigation results to confirm the diagnosis, evaluate treatment response, and construct the case narrative. Adult varicella is up to 25 times more severe than in children. The virus is transmitted via the respiratory tract with an incubation period of 10–21 days. Physical stress and disruption of circadian rhythms may impair immune response. Lesions typically start on the face and scalp and spread to the body. A This case highlights a presentation of adult varicella with systemic involvement. Early antiviral treatment can improve prognosis.
Patofisiologi Selulit Dhillon, Jesryn; Jusuf, Nelva Karmila
Cermin Dunia Kedokteran Vol 50 No 12 (2023): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i12.901

Abstract

Cellulite is a topographic change of the skin commonly found in the buttocks and thighs in the majority of post-pubertal women. Cellulite in males is usually accompanied by hormonal disorders. Histological changes were found in the dermis, adipose tissue, and septa. The pathophysiology of cellulite is yet to be determined, several factors are suspected.
Non–invasive vulvovaginal rejuvenation: A review Dhillon, Jesryn; Jusuf, Nelva Karmila
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 8, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Non–invasive vulvovaginal rejuvenation is a promising option for women who want to restore the appearance and function of the vagina. Vaginal atrophy and vulvovaginal laxity are caused by several circumstances, including ageing, menopause, delivery, and others. Until now, non–invasive vulvovaginal rejuvenation has not been medically indicated, but it is estimated to be the focus of cosmetic dermatology in the future. Discussion: Non–invasive vulvovaginal rejuvenation can be divided into two methods: using energy-based devices and injectables. Carbon dioxide, Erbium:YAG laser and radiofrequency are the commonly used energy-based devices. Injectables most frequently used are hyaluronic acid and platelet–rich plasma. Some additional therapies, such as vaginal bleaching and vaginal tightening, are available to complement the available modalities. Several proposed combination treatments might be used to improve treatment outcomes. Side effects and complications reported are mild, but no consensus has approved its long–term effects. The legal aspect is not to be forgotten during the whole procedure. Conclusion: Further multicenter, double–randomized studies are needed to determine these procedures' safety and efficacy.
Co-Authors Berlian, Guntur Cut Putri Hazlianda Dalimunthe, Dina A Dina Arwina Dalimunthe, Dina Arwina Hutagalung, Patricia Jusuf, Nelva Karmila Lubis, Flora Marita Nasution, Khairina Putra, Imam Budi Sinaga, Riana Miranda