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All Journal Jurnal Kesehatan Medika Saintika Journal of Pharmaceutical and Sciences.
Dwijayanti, Anisa
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Other

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PENGARUH PEMBERIAN OAT LOTION TERHADAP PENGURANGAN SKALA PRURITUS PADA PASIEN HEMODIALISA Dwijayanti, Anisa; Rivani, Dyah; Rismanta, Agus
Jurnal Kesehatan Medika Saintika Vol 16, No 1 (2025): Juni 2025
Publisher : Stikes Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jkms.v16i1.3133

Abstract

Pruritus merupakan salah satu keluhan kulit yang sering dialami oleh pasien hemodialisis akibat akumulasi toksin uremik dan gangguan keseimbangan elektrolit. Kondisi ini dapat menurunkan kualitas hidup pasien secara signifikan. Salah satu pendekatan non-farmakologis yang potensial untuk mengurangi pruritus adalah penggunaan oat lotion, yang memiliki sifat antiinflamasi, antipruritus, dan pelembap. Penelitian ini bertujuan untuk mengetahui efektivitas oat lotion dalam menurunkan skala pruritus pasien hemodialisa. Penelitian ini menggunakan metode studi kasus pada seorang pasien Chronic Kidney Disease (CKD) yang menjalani hemodialisis rutin dua kali seminggu di RS PKU Muhammadiyah Yogyakarta. Intervensi berupa aplikasi oat lotion dua kali sehari selama dua minggu yang diukur menggunakan Numeric Rating Scale (NRS) dan dievaluasi selama empat kali pertemuan. Terdapat penurunan skor pruritus dari skor 7 menjadi 5, serta perbaikan kondisi kulit kering berskala 9 menjadi 5. Hal ini menunjukan pemberian oat lotion efektif dalam menurunkan skala pruritus.Kata kunci : Oat lotion, Pruritus, Hemodialisis, Terapi Non-Farmakologis
Optimasi Konsentrasi BHT untuk Menjaga Stabilitas Pigmen Alami pada Sediaan Cream Blush Ekstrak Hemigraphis colorata Ratih, Hestiary; Sutarna, Titta Hartyana; Al-Hakim, Nur Achsan; Dwijayanti, Anisa
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1139

Abstract

The use of natural dyes from Hemigraphis colorata Hall. extract as cosmetic dyes faces stability challenges due to oxidative degradation. This study aims to test the effect of Butylated Hydroxytoluene (BHT) antioxidant concentration on the physical stability and color of cream blush formulations. H. colorata leaves were extracted by maceration and lyophilization, then formulated into four cream blush preparations with varying concentrations of BHT: without BHT (F0), 0.0075% (F1), 0.05% (F2), and 0.1% (F3). Physical stability of the formulations was evaluated for 28 days through organoleptic testing, homogeneity, pH, viscosity, spreadability, adhesion, and color stability using UV-Visible spectrophotometry. The results showed that all formulations met the physical standards for topical preparations. However, F2 (0.05%) and F3 (0.1%) successfully maintained color stability with minimal shifts. This study concludes that BHT can effectively maintain the physical stability of cream blush formulations based on H. colorata extract, with 0.05% (F2) being the optimal BHT concentration (the lowest effective concentration), based on considerations of effectiveness, safety, and cost, proven to be optimal in protecting natural pigments from degradation. These results provide important information for the development of safe, high-quality natural cosmetic products with a longer shelf life.
Co-Authors Hartyana Sutarna, Titta Hestiary Ratih Nur Achsan Al-Hakim Rismanta, Agus Rivani, Dyah