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Uji Stabilitas Fisik dan Kimia Tablet Paracetamol dengan Berbagai Variasi Bahan Pengikat Muhammad Reihan Ridha; Muhammad Romansyah Khatami; Nor Latifah
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3111

Abstract

Tablets represent one of the most widely utilized solid pharmaceutical dosage forms, in which both physical and chemical stability parameters play a critical role in ensuring product quality and therapeutic efficacy throughout the shelf life. The stability of tablet formulations is influenced by various factors, including the type and concentration of binders used during manufacturing. This review aims to evaluate the effects of natural binders—specifically durian seed starch, cempedak seed starch, and mucilage from Dioscorea esculenta (lesser yam) tuber starch—on the quality of paracetamol tablets based on findings from the scientific literature. A systematic literature search was conducted using various academic databases. The reviewed studies revealed that all tested natural binders generally met the physical quality parameters outlined in the Indonesian Pharmacopoeia. However, increasing binder concentrations was associated with prolonged disintegration times and reduced solubility of the active pharmaceutical ingredient (API). These findings highlight the importance of selecting appropriate binder types and optimizing their concentrations to ensure effective drug release and maintain formulation stability during storage.
Program Sapa Sehat ke Rumah: Strategi Pemeriksaan Kesehatan Door to Door untuk Deteksi Dini Hipertensi dan Diabetes pada Lansia Herda Ariyani; Abu Dzar Alghifary; Anisa Diva Ramadhani; Dhiya Shoufi Sahaja; Gina Aqifah; Muhammad Haikal Rifqy; Muhammad Romansyah Khatami; Nailia Nur Isma Sumarno; Noor Kamalliyah Kamalliyah; Prilia Candra Noorazmi; Risma Yulidah Yulidah; Sri Rezeki Solehah; Susan; Tri Indah Lestari; Zalmiati
Borneo Community Development Vol. 6 No. 1 (2026)
Publisher : Universitas Muhammadiyah Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35747/bcd.v6i1.1510

Abstract

Non-communicable diseases (NCDs) such as hypertension, diabetes mellitus, hypercholesterolemia, and hyperuricemia remain major health problems in Indonesia, especially among the elderly. In Balangan Regency, South Kalimantan, hypertension has been reported as the most common NCD among elderly patients in the Lampihong Health Center area, while limited healthcare access in rural villages such as Matang Hanau further increases the risk of late detection and complications. To address this urgent issue, the Community Service Program (KKN) in Matang Hanau Village, Lampihong District, was implemented through a door-to-door health screening strategy aimed at early identification of NCD risk factors. The program involved coordination with village officials, collaboration with Lampihong Health Center and Matang Hanau Sub-Health Center (Pustu), provision of health education, blood pressure and blood sugar checks, and distribution of educational leaflets combined with direct consultation. A total of 258 residents participated, with most elderly showing above-normal blood pressure and blood sugar levels. The program successfully increased community awareness and willingness to undergo routine health checks, highlighting the urgency of strengthening community-based screening as a sustainable approach to reducing the burden of NCDs in Balangan Regency.