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POTENSI EKSTRAK ETANOL DAUN SUKUN (Artocarpus altilis) SEBAGAI BAHAN TABIR SURYA DENGAN PENENTUAN NILAI Sun Protection Factor (SPF) SECARA In Vitro Jariah, Ainun; Masri, Anshari; Rukman, Wira Yustika; Muhammad Guntur; Andi Budirohmi; dupppa, muhammad taufiq
Jurnal Kesehatan Yamasi Makassar Vol 9 No 2 (2025): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v9i2.384

Abstract

This study aims to determine the value of Sun Protection Factor (SPF) In Vitro Leaf Extract Ethanol Breadfruit (Artocarpus altilis) as a Material Sunscreen. The study design was an observational laboratory that carried out in the Laboratory Farmakognosi-fitokimia Study Pharmacy Faculty of Medicine and Health, Muhammadiyah University. In a study determining the SPF in vitro is done by making a solution of ethanol extract of leaves of breadfruit with a concentration of 25 ppm, 50 ppm, 100 ppm and 200 ppm were then the absorbance is measured using a UV-Vis spectrophotometer at a wavelength of 290-320 nm at intervals of 5 nm. The results showed that the ethanol extract of leaves of breadfruit at a concentration of 25 ppm by 1600, 50 ppm at 2.5966, 6.9166 at 100 ppm, and 200 ppm of 50.6811. Based on the results of this study concluded that the ethanol extract of leaves of breadfruit can be used as a sunscreen active ingredient in concentrations above 50 ppm (SPF value> 2).
UJI EFEKTIVITAS EKSTRAK ETANOL BUAH BINTARO (Cerbera odollam Gaerthn) TERHADAP PENURUNAN GLUKOSA DARAH PADA TIKUS PUTIH (Rattus norvegicus) Masri, Anshari; duppa, muhammad taufiq; Rukman, Wira Yustika; Syafruddin; Sitti Nurjannah; Delvi Sara JIhan; Ermawati; dupppa, muhammad taufiq
Jurnal Kesehatan Yamasi Makassar Vol 9 No 2 (2025): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v9i2.386

Abstract

This study aims to determine the efectivity of Bintaro Fruit (Cerbera odollam gaerthn) Ethanol Extract Against Blood Glucose Decrease in White Rats (Rattus Norvegicus. The research design used was an experimental laboratory carried out in the pharmacology laboratory of the Department of Pharmacy, Pancasakti University. This study used 15 rats. male white rats were divided into 5 groups consisting of group I as a negative control by giving 1% w/v Na.CMC suspension, groups II, III, IV as a treatment group given Bintaro Fruit extract 1% w/v, 3% w/v, 5% w/v And group V was given Glibenclamide suspension as a positive control.The results showed that the percentage reduction in blood glucose for negative control, treatment and positive groups was 11.37%, 32.03%, 65, respectively. 46%, 86.15%, 95.5% The most effective concentration was 5% w/v concentration with an average value of 86.15% reduction, but it has not been able to match the effectiveness of Glibenclamide. in statistical testing using the Graphad Prims program for an alpha rate of 0.05, P value of 0.0001 is significant, the F value is 608.3.