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FORMULASI GEL EKSTRAK DAUN KEMANGI (Ocinum Sanctum L.) SEBAGAI SEDIAAN HAND SANITIZER TAHUN 2022 Kemal, Amir
Journal of Pharmacy Tiara Bunda Vol. 2 No. 2 (2022): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.57

The formulation has been carried out antiseptic hand gel preparation of the ethanol extract of leaves of basil (Ocimum sanctum L.) using a combination of Carbopol 940 and HPMC base accompanied by physical stability test preparation gel. This study aims to determine the physical stability of the combination of base and determine the concentration of a good combination of base carbopol 940 and HPMC in antiseptic hand gel formulation ethanol extract of basil (Ocimum sanctum L.). Physical stability of the gel formulation is determined by observation of changes in color, smell, shape, pH, homogeneity, and syneresis. The results showed that sediaaan antiseptic hand gel can be said to be stable on the parameters of homogeneity where there are no solid particles in the preparation. Sinersis stable in which there is no liquid on the surface of the gel. Stable in good dispersive power parameters, namely Formula I, II, and III have the diameter of no more than 3-5 cm. While the results of the measurement of pH, a combination of carbopol 940 gel preparations and HPMC with a concentration of 0.5% and 0.25% of its pH is stable in storage and has a pH in accordance with the physiological skin pH is 4.5-6.5. Based on the results obtained, the base 940 and HPMC carbopol combination with a concentration of 0.5% and 0.25% had good physical stability

EVALUASI PENGGUNAAN OBAT BEBAS DAN BEBAS TERBATAS Kemal, Amir
Journal of Pharmacy Tiara Bunda Vol. 1 No. 1 (2021): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i1.60

Self-medication is part of the community's efforts to overcome minor illnesses by using over-the-counter drugs, limited over-the-counter medicines and mandatory pharmacy medicines without consulting a doctor first. This study was conducted to determine the evaluation of the use of over-the-counter and limited-free drugs in Cipayung village based on knowledge and rationality of drug use. Respondents were selected based on predetermined inclusion and exclusion criteria. Data were collected through interviews using a questionnaire that had been tested for validity and reliability. The number of respondents obtained were 110 respondents with consecutive sampling method from five pharmacies in Cipyaung Village, Cipayung District, Depok City. The data obtained from the results of filling out the questionnaire were collected and analyzed descriptively. Then coding is carried out on each answer by giving a certain score or value. Then the data are grouped according to their respective characteristics and displayed in tabular form. The results showed that the patient's level of knowledge was 37.3% classified as poor, 39.1% classified as moderate and 23.6% classified as good. The use of self-medication was 17.3% irrational and 82.7% rational. Based on the results of the study, it was found that the patient's level of knowledge was moderate with a percentage of 39.1%. While the rationality of self-medication is considered rational with a percentage of 82.7%.

HUBUNGAN PELAYANAN INFORMASI OBAT DENGAN TINGKAT KEPATUHAN PASIEN HIPERTENSI Kemal, Amir
Journal of Pharmacy Tiara Bunda Vol. 1 No. 2 (2021): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.63

Drug information services are very important in supporting the management and use of drugs rationally. Drug information services are very necessary, especially since many patients have not received adequate drug information. The purpose of this study was to see the relationship between drug information services and the level of compliance of hypertensive patients at the Sikumana Health Center in Kupang City. This study is a non-experimental study with a descriptive research design with a prospective approach. The sampling technique used was purposive sampling. Respondents in this study were all patients suffering from high blood pressure (Hypertension) at the Sikumana Health Center in Kupang City with a total of 50 people. Furthermore, the data was analyzed using Kendal's Tau-B correlation analysis with a significance level of p <0.005. Based on the results of statistical tests using Kendal's Tau-B correlation, a significant value of 0.004 was obtained, stating that there was a relationship between drug information services and the level of compliance of hypertensive patients, with a correlation coefficient value of 0.348 with a degree of relationship that is sufficient correlation, so it can be concluded that there is a relationship between drug information services and the level of compliance of hypertensive patients and the degree of relationship that is sufficient correlation.

FORMULASI DAN UJI SIFAT LILIN AROMATERAPI KOMBINASI MINYAK ATSIRI DAUN KEMANGI (OCINUM SANCTUM L) DAN SEREH (CYMPOGOGON ATRATUS) Kemal, Amir
Journal of Pharmacy Tiara Bunda Vol. 2 No. 1 (2022): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i1.73

In the current conditions of the Covid-19 pandemic, aromatherapy candles have become a necessity for the community as an alternative treatment by utilizing natural ingredients whose popularity is increasing. One of natural ingredients used for aromatherapy is basil and lemongrass. This study aimed to determine whether the essential oil combination of basil leaves (Ocimum sanctum L) and lemongrass (Cymbopogon citratus) can be formulated into aromatherapy candles. The experiment was conducted in the laboratory. The essential oils of basil and lemongrass were gainded from E-Commerce and processed through Thin Layer Chromatography. Silica gel stationary phase, chloroform-benzene mobile phase for basil leaves and toluene-ethyl acetate mobile phase for lemongrass samples. Then the materials (for making aromatherapy candle) were made in three different concentrations of formula I (3%: 20%), formula II (2%: 10%), and formula III (1%: 5%). Test of physical properties of the materials included organoleptic test, test melting point, burn times test and preference test from 20 respondents. The results of the test of the materials for aromatherapy candle showed that there was an affect on the physical properties of aromatherapy candles. Based on the findings of physical properties test, formula III resulted the best because of high melting test point and the longest burning time. Formula I was widely preferred for greater concentration of essential oils

Skrining Aktivitas Antibakakteri Fraksi Kulit Buah Durian (Durio zibhetimus M) Kemal, Amir
Journal of Pharmacy Tiara Bunda Vol. 3 No. 2 (2023): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.87

A screening study of antibacterial activity of Durio zibethinus M fraction on Escherhicia coli bacteria and Staphylococcus aureus bacteria has been carried out. This study aims to determine the inhibitory effect of durian peel extract on Escherhicia coli bacteria and Staphylococcus aureus bacteria, to determine the most active fraction in inhibiting the growth of Escherhicia coli bacteria and Staphylococcus aureus bacteria and to find out the most active class of compounds against antibacterial activity.The fraction on Duiro zibethinus M was carried out by vacuum liquid chromatography method..Ethyl acetate and methanol extract have antibacterial activity characterized by the presence of clear inhibition zones in the paper disk area, for n-hexane extract does not have a inhibitory effect on bacteria. The results of the inhibition of ethyl acetate extract, which is 17.13 mm are strongly marked for Escherichia coli bacteria and moderate inhibitory capacity of 7.34 mm for Staphylococcus aureus bacteria. Whereas the inhibitory results of methanol extract were 15.11 mm which means that it is strong for Escherichia coli bacteria and strong inhibition power of 11.45 mm for Staphylococcus aureus bacteria. Fraction 2 has antibacterial activity in Staphylococcus aureus bacteria characterized by the presence of clear inhibition zones in the piper disk area, whereas in Escherichia coli bacteria there is no inhibiting fraction. The results of the inhibition of fraction 2 is 9.96 mm which means that it is medium for Staphylococcus aureus bacteria. On the results of identification fractionation of Durio zibethunus M fruit skin showed function as an antibacterial, namely the Flavonoid compound

FORMULASI DAN EVALUASI SABUN CAIR EKSTRAK DAUN SIRIH MERAH (Piper crocatum Riuz & Pav.) SERTA UJI AKTIVITAS SEBAGAI ANTISEPTIK TERHADAP BAKTERI Staphylococcus aureus Kemal, Amir
Journal of Pharmacy Tiara Bunda Vol. 5 No. 1 (2025): Vol. 5 No. 1 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

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Sirih merah merupakan salah satu tanaman obat berkhasiat. Berdasarkan penelitian ilmiah, daun sirih merah memiliki antibakteri karena mengandung flavonoid, alkaloid, saponin, dan tannin. Penelitin ini bertujuan untuk membuat sediaan sabun cair sebagai antiseptik dan mengetahui kemampuan sediaan sabun cair dalam menghambat pertumbuhan bakteri Staphylococcus aureus. Jenis penelitian yaitu eksperimental laboratorium. Formulasi sabun cair ekstrak etanol daun sirih merah dengan konsentrasi 2,5%, 5%, dan 7,5% dilakukan pengujian iritasi, organoleptis, pH, tinggi busa, dan bobot jenis. Pengujian yang dilakukan terhadap bakteri Staphylococcus aureus menggunakan metode difusi. Hasil pengujian mutu sabun cair memenuhi persyaratan sesuai standar yang ditetapkan SNI. Hasil pengamatan yang diperoleh dengan rata-rata zona hambat untuk konsentrasi 2,5% adalah 15,30 mm, 5% adalah 15,60 mm, 7,5 % adalah 16,86 mm, kontrol positif adalah 30,86 mm, sedangkan kontrol negatif tidak terbentuk zona hambat. Kesimpulan penelitian ini bahwa ekstrak daun sirih merah (Piper crocatum Riuz & Pav.)memiliki daya hambat terhadap bakteri Staphylococcus aureus, yaitu dengan konsentrasi 2,5%, 5%, dan 7,5% masuk dalam kategori kuat. Disarankan kepada peneliti selanjutnya untuk meneliti uji aktivitas antibakteri ekstrak daun sirih merah terhadap jenis bakteri lain.

Liquid Soap Formulation Ethanol Extract Avocado Skin (Persea americana) Against Bacteria Staphylococcus aureus Suryani, Ade Irma; Ambarsari, Niati; Oktaviani, Milla; Rerung, Lola’ Tulak; Sari, Rahayu Mustika; Kemal, Amir; Dewi, Hasna
ENDLESS: INTERNATIONAL JOURNAL OF FUTURE STUDIES Vol. 6 No. 1 (2023): ENDLESS : International Journal of Future Studies
Publisher : Global Writing Academica Researching & Publishing

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Avocado peels contain Flavonoid compounds and alkaloids as antibacterial. In this study, the ethanol extract of Avocado peels was formulated as a liquid soap using concentrations of FI (1%), FII (3%) and FIII (5%). This study aimed to formulate a liquid soap from a sample of Avocado peel extract against the antibacterial activity ofStaphylococcus aureususing the agar diffusion method in wells. Physical evaluation of liquid soap preparations includes several parameters, namely organoleptic tests including odour, shape and colour, pH test, foam stability test, viscosity test and homogeneity test. The results obtained from testing liquid soap using ethanol extract of Avocado peels with varying concentrations of 1%, 3% and 5% can inhibit the growth of Staphylococcus aureus bacteria, namely 1% = 19.6, 3% = 21.6 and 5% = 25.8. Based on the results of this study it can be concluded that the ethanol extract of Avocado peels (Persea americana) can be formulated in the form of liquid soap and is effective against inhibition of Staphylococcus aureus bacteria. In this study, FIII fulfilled the physical quality evaluation test and had activity as an antibacterial, with the resulting inhibition zone at a concentration of 5% = 26.6 mm, a powerful category.

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