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Journal : Pharmaceutical Science Journal

Analisa Penggunaan Antibiotik Pada Pasien Pneumonia Anak Dan Remaja Di Rs Bhayangkara Lemdiklat Polri Periode Januari-Desember 2024 Nurlela, Nurlela; Dewantoro, Agung; Susanti, Debi; Aulia, Gina
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1174

Abstract

Pneumonia attacks the respiratory tract and is one of the dangerous infections that can potentially cause high mortality rates, especially in children and adolescents. The objective of this study were to analyze the pattern of antibiotics use in pediatric and adolescent pneumonia patients at an inpatient ward, Bhayangkara Lemdiklat Polri Hospital. Methods:This was a descriptive, observational and cross-sectional study. We employed a total sampling method, collecting data from patient medical records retrospectively. Results The findings revealed that most of the patients were toddlers, 0–5 years (43%) Table 1.Length of stay and distribution of pneumonia patients in MMCPS Age Prevalence n(%) Male Patient ratioTime interval Adult N=232 Working daysper dayRange (year) 30%, followed by male gender (53%), with average length of stay from 1 to 7 days (79%). The most frequent comorbidity was anaemia (30%). The antibiotic utilized was predominantly injectables (85%) given as monotherapy 85% and under the class of cephalosporin category (66%). Ceftriaxone (59%).Conclusion: was the most commonly used antibiotic. The findings of this study reveal that the antibiotic prescription for pediatric and adolescent pneumonia patients at Bhayangkara Lemdiklat Polri Hospital are in line with previous research results, where ceftriaxone is the most commonly used as a single-agent injectable antibiotic.
FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN MASKER GEL PEEL- OFF DARI EKSTRAK BUAH STROBERI (FRAGARIA SP) DENGAN METODE DPPH Utami, Anissa; Pomalingo, Dwina Ramadhani; Bastian, Irvan; Winarni, Gandes; Susanti, Debi; Yuristiawan, Yuristiawan; Alhabzy, Raihan Wisnu
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1152

Abstract

Strawberries (Fragaria sp.) are plants rich in bioactive compounds such as anthocyanins, flavonoids, ellagic acid, and vitamin C, which act as natural antioxidants. This study aimed to formulate and evaluate peel-off gel mask preparations containing strawberry extract and to test their antioxidant activity using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The research was conducted experimentally with three extract concentrations: F1 (2%), F2 (3%), and F3 (4%). The formulations were evaluated through organoleptic testing, homogeneity, pH, drying time, and spreadability. Antioxidant activity was analyzed based on IC50 values. The results showed that all formulations remained stable organoleptically during 4 weeks of storage, were homogeneous, had pH values of 4.72–5.37, drying times of 15–19 minutes, and spreadability between 5.1–6.1 cm. Antioxidant activity tests revealed that F1 had an IC50 value of 63.65 μg/mL, F2 of 57.75 μg/mL, and F3 showed the strongest activity with an IC50 value of 41.77 μg/mL, which is categorized as very strong. In conclusion, the F3 formulation (4%) demonstrated the best physical stability and the highest antioxidant activity.
HUBUNGAN TINGKAT PENGETAHUAN IBU TERHADAP PERILAKU SWAMEDIKASI DIARE PADA ANAK DI WILAYAH RW 002 KELURAHAN PETOGONGAN KECAMATAN KEBAYORAN BARU KOTA JAKARTA SELATAN Dewantoro, Agung; Ismaya, Nurwulan Adi; Nurlela, Nurlela; Susanti, Debi; Priono, Fransiskus Agus; Nurina, Sheima Sukmarina
PHRASE (Pharmaceutical Science) Journal Vol 6, No 1 (2026)
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v6i1.1254

Abstract

ABSTRAKDiare adalah penyakit yang ditandai dengan pengeluaran tinja yang tidak normal berupa peningkatan volume, keenceran, serta frekuensi buang air besar lebih dari 3 kali sehari. Menurut WHO, diare merupakan penyakit yang menyebabkan kematian terbanyak pada anak. Swamedikasi adalah pengobatan sendiri semua penyakit yang tergolong ringan mulai dari gejala sampai dengan pemilihan obat-obatan. Tujuan penelitian ini untuk mengetahui ada atau tidaknya hubungan antara pengetahuan ibu mengenai diare pada anak dengan perilaku ibu terhadap swamedikasi diare pada anak di Wilayah RW 002 Kelurahan Petogogan Kecamatan Kebayoran Baru Kota Jakarta Selatan. Metode yang digunakan adalah metode deskriptif dengan teknik pengambilan sampel menggunakan total sampling. Hasil penelitian ini menunjukkan bahwa pengetahuan ibu mengenai diare pada anak dalam kategori baik sebanyak 119 responden (84,40%), pengetahuan ibu mengenai swamedikasi diare pada anak dalam kategori baik sebanyak 84 responden (59,57%), perilaku ibu mengenai swamedikasi diare pada anak dalam kategori cukup sebanyak 102 responden (72,34%). Kesimpulan dari penelitian ini menunjukkan bahwa tidak terdapat hubungan yang berarti pada tingkat pengetahuan ibu mengenai diare pada anak dan perilaku ibu terhadap swamedikasi diare pada anak dengan nilai uji spearman’s 0,123. Saran diharapkan ibu dapat meningkatkan perilaku swamedikasi diare dengan baik, sehingga ketika anak terkena diare dapat ditangani dengan tepat.