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All Journal Jurnal Farmamedika (Pharmamedica Journal) Edu Masda Journal Pharmaceutical Science Journal
Susanti, Debi
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Pharmaceutical Science Journal

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Analisa Penggunaan Antibiotik Pada Pasien Pneumonia Anak Dan Remaja Di Rs Bhayangkara Lemdiklat Polri Periode Januari-Desember 2024 Nurlela, Nurlela; Dewantoro, Agung; Susanti, Debi; Aulia, Gina
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1174

Abstract

Pneumonia attacks the respiratory tract and is one of the dangerous infections that can potentially cause high mortality rates, especially in children and adolescents. The objective of this study were to analyze the pattern of antibiotics use in pediatric and adolescent pneumonia patients at an inpatient ward, Bhayangkara Lemdiklat Polri Hospital. Methods:This was a descriptive, observational and cross-sectional study. We employed a total sampling method, collecting data from patient medical records retrospectively. Results The findings revealed that most of the patients were toddlers, 0–5 years (43%) Table 1.Length of stay and distribution of pneumonia patients in MMCPS Age Prevalence n(%) Male Patient ratioTime interval Adult N=232 Working daysper dayRange (year) 30%, followed by male gender (53%), with average length of stay from 1 to 7 days (79%). The most frequent comorbidity was anaemia (30%). The antibiotic utilized was predominantly injectables (85%) given as monotherapy 85% and under the class of cephalosporin category (66%). Ceftriaxone (59%).Conclusion: was the most commonly used antibiotic. The findings of this study reveal that the antibiotic prescription for pediatric and adolescent pneumonia patients at Bhayangkara Lemdiklat Polri Hospital are in line with previous research results, where ceftriaxone is the most commonly used as a single-agent injectable antibiotic.
FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN MASKER GEL PEEL- OFF DARI EKSTRAK BUAH STROBERI (FRAGARIA SP) DENGAN METODE DPPH Utami, Anissa; Pomalingo, Dwina Ramadhani; Bastian, Irvan; Winarni, Gandes; Susanti, Debi; Yuristiawan, Yuristiawan; Alhabzy, Raihan Wisnu
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1152

Abstract

Strawberries (Fragaria sp.) are plants rich in bioactive compounds such as anthocyanins, flavonoids, ellagic acid, and vitamin C, which act as natural antioxidants. This study aimed to formulate and evaluate peel-off gel mask preparations containing strawberry extract and to test their antioxidant activity using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The research was conducted experimentally with three extract concentrations: F1 (2%), F2 (3%), and F3 (4%). The formulations were evaluated through organoleptic testing, homogeneity, pH, drying time, and spreadability. Antioxidant activity was analyzed based on IC50 values. The results showed that all formulations remained stable organoleptically during 4 weeks of storage, were homogeneous, had pH values of 4.72–5.37, drying times of 15–19 minutes, and spreadability between 5.1–6.1 cm. Antioxidant activity tests revealed that F1 had an IC50 value of 63.65 μg/mL, F2 of 57.75 μg/mL, and F3 showed the strongest activity with an IC50 value of 41.77 μg/mL, which is categorized as very strong. In conclusion, the F3 formulation (4%) demonstrated the best physical stability and the highest antioxidant activity.
Co-Authors Agung Dewantoro Alhabzy, Raihan Wisnu Andriyani Rahmah Fahriati Aulia, Gina Bastian, Irvan Gandes Winarni Muhammad Zulfikar Adha Mutiasih , Pipit Nurlela Nurlela Pomalingo, Dwina Ramadhani Susilowatie, Oni Utami, Anissa Yuristiawan, Yuristiawan