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All Journal Jurnal Biologi Tropis
Adidaifa, Muhammad Fikri
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Literature Review: Skin Aging in the Ederly Population Salsabila, Baiq Ghefira Rojwani Putri; Hardiant, Excell Defry; Suryani, Elsa Indah; Salsabila, Tsania Zulfa; Savitri, Puti Amelia; Untari, Lania Pradiva; Paradiesta, Andi Frieskha Naurah; Angelita, Puja Rizkina; Adidaifa, Muhammad Fikri; Musyarof, Disa Fadil; Hidayatullah, Audi
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.10032

Abstract

Skin aging is a progressive degenerative process characterized by a decline in the structural and functional capacity of the skin to maintain its protective, regenerative, and homeostatic roles. It is influenced by both intrinsic factors, such as genetics, telomere shortening, mitochondrial dysfunction, hormonal changes, microbiota alterations, and decreased vitamin D production, and extrinsic factors, including ultraviolet radiation, pollution, smoking, oxidative stress, and lifestyle. Clinically, skin aging presents with thinning, dryness, loss of elasticity, fine to deep wrinkles, pigmentary changes, and benign skin lesions. The increasing elderly population, particularly in Indonesia, highlights the growing importance of addressing skin aging due to its impact not only on physical health but also on psychosocial well-being and quality of life. Management strategies include pharmacological approaches such as sunscreens, moisturizers, vitamin D and collagen supplementation, retinoids, and hormone replacement therapy, as well as non-pharmacological interventions including antioxidant-rich nutrition, hydration, allergen avoidance, wound care, dietary restriction, facial massage, and aesthetic procedures like stem cell therapy. Early prevention, timely recognition, and comprehensive management of skin aging are essential to support healthy aging and maintain the quality of life among the elderly.
Hypothyroidism: A Literature Review Hardiant, Excell Defry; Adidaifa, Muhammad Fikri; Salsabila, Tsania Zulfa; Maulana, Muhammad Rafi; Salsabila, Baiq Ghefira Rojwani Putri; Untari, Lania Pradiva; Suryani, Elsa Indah; Paradiesta, Andi Frieskha Naurah; Savitri, Puti Amelia; Rahmat, Basuki
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.10033

Abstract

Hypothyroidism is a condition in which the thyroid gland is unable to produce enough hormones to meet the body's needs. This condition causes a slowed metabolism, which can lead to various symptoms such as fatigue, weight gain, dry skin, hair loss, constipation, cold intolerance, and facial puffiness. Given the widespread impact of hypothyroidism and the potential for serious complications, special attention is needed for early detection, diagnosis, and effective treatment of hypothyroidism. This literature review was conducted using journal review methods and data searches through sources such as PubMed, Google Scholar, and ScienceDirect. The search used the keywords "hypothyroidism," "hypothyroid," "thyroid gland," and "Hashimoto's thyroiditis." The results of the literature review found that the main cause of hypothyroidism is Hashimoto's thyroiditis, an autoimmune disease in which antibodies attack the thyroid gland. Hypothyroidism is diagnosed by examining elevated TSH and decreased free T4 levels, as well as anti-TPO antibody tests to detect Hashimoto's thyroiditis. Treatment for hypothyroidism generally involves administering levothyroxine, a synthetic thyroid hormone, to replace the deficient hormone and normalize metabolic function. Healthy lifestyle support, such as diet and stress management, is also important to help optimally manage this condition. In conclusion, hypothyroidism is characterized by a decrease in thyroid hormone production and preventive management is pharmacological in the form of levothyroxine, while non-pharmacological management is in the form of regulating food intake.
Co-Authors Angelita, Puja Rizkina Basuki Rahmat Masdi Siduppa Hardiant, Excell Defry Hidayatullah, Audi Maulana, Muhammad Rafi Musyarof, Disa Fadil Paradiesta, Andi Frieskha Naurah Salsabila, Baiq Ghefira Rojwani Putri Salsabila, Tsania Zulfa Savitri, Puti Amelia Suryani, Elsa Indah Untari, Lania Pradiva