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Analisis Kompetensi dan Kepuasan Kerja Terhadap Kinerja Karyawan melalui Motivasi sebagai Variabel Intervening pada PT. Astellas Pharma Indonesia Maulana, Muhammad Rafi; Sriyono, Sriyono
Jurnal Ilmiah Akuntansi dan Keuangan Vol. 12 No. 1 (2023): Jurnal Ilmiah Akuntansi dan Keuangan
Publisher : LP3M Universitas Putra Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32639/jiak.v12i1.175

Abstract

Penelitian ini memiliki tujuan untuk mengetahui dan menjawab permasalahan-permasalahan yang terjadi diperusahaan terkait dengan kompetensi, kepuasan kerja, moitvsasi dan kinerja karyawan pada perusahaan. Metode penelitian yang dilakukan pada penelitian ini adalah kuantitatif dengan mengambil sampel menggunakan tehnik Proposive sampling yang ditentukan yaitu pada karyawan bagian marketing di perusahaan dengan menggunakan sampel sebanyak 100 karyawan di perusahaan. Hasil Penelitian yang dihasilkan menunjukkan bahwa kompetensi yang dimiliki oleh karyawan dapat meningkatkan kinerja karyawan di perusahaan seperti ketrampilan yang dimiliki karyawan, pengetahuan yang mendalam terkait dengan produk dan kegiatan pemasaran yang dimiliki karyawan dan difasilitasi oleh perusahaan, kepuasan kerja yang diterima oleh karyawan juga berdampak positif terhadap kinerja karyawan sehingga dapat meningkatkan penjualan perusahaan, motivasi juga menjadi faktor pendukung yang dapat meningkatkan kinerja karyawan seperti kebutuhan yang diinginkan oleh karyawan yang berkaitan dengan perusahaan seperti penghargaan dan kebutuhan fisik sehingga kinerja karyawan dapat meningkatkan dan dapat mempengaruhi pekerjaan mereka.      
Diagnosis and Management of Acute Respiratory Tract Infections (Pharyngitis and Laryngitis) Salsabila, Ericha Zabrina; Damayanti, Ida Ayu Andara; Wiguna, I Made Danuarta; Maulana, Muhammad Rafi; Ajmala, Indana Eva
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.10013

Abstract

Acute respiratory tract infections (ARI), including pharyngitis and laryngitis, remain a highly prevalent disease in Indonesia and even globally. These respiratory infections are caused by the bacterium Streptococcus pyogenes, also known as Streptococcus beta hemolyticus group A. The purpose of this literature review was to identify acute respiratory tract infections (pharyngitis and laryngitis). Pharyngitis is more common in children and adolescents, while laryngitis is more common in infants and children. The review concluded that Streptococcus pyogenes is the main cause of bacterial pharyngitis, while laryngitis is an inflammation of the larynx that can be caused by a variety of factors, including bacterial or viral infections as well as non-infectious factors like irritation or trauma. In conclusion, a thorough understanding of acute pharyngitis and laryngitis, including causative factors, clinical manifestations, management, and prevention, is essential for both medical personnel and the general public in an effort to reduce the burden of these diseases and improve overall upper respiratory health.
Hypothyroidism: A Literature Review Hardiant, Excell Defry; Adidaifa, Muhammad Fikri; Salsabila, Tsania Zulfa; Maulana, Muhammad Rafi; Salsabila, Baiq Ghefira Rojwani Putri; Untari, Lania Pradiva; Suryani, Elsa Indah; Paradiesta, Andi Frieskha Naurah; Savitri, Puti Amelia; Rahmat, Basuki
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.10033

Abstract

Hypothyroidism is a condition in which the thyroid gland is unable to produce enough hormones to meet the body's needs. This condition causes a slowed metabolism, which can lead to various symptoms such as fatigue, weight gain, dry skin, hair loss, constipation, cold intolerance, and facial puffiness. Given the widespread impact of hypothyroidism and the potential for serious complications, special attention is needed for early detection, diagnosis, and effective treatment of hypothyroidism. This literature review was conducted using journal review methods and data searches through sources such as PubMed, Google Scholar, and ScienceDirect. The search used the keywords "hypothyroidism," "hypothyroid," "thyroid gland," and "Hashimoto's thyroiditis." The results of the literature review found that the main cause of hypothyroidism is Hashimoto's thyroiditis, an autoimmune disease in which antibodies attack the thyroid gland. Hypothyroidism is diagnosed by examining elevated TSH and decreased free T4 levels, as well as anti-TPO antibody tests to detect Hashimoto's thyroiditis. Treatment for hypothyroidism generally involves administering levothyroxine, a synthetic thyroid hormone, to replace the deficient hormone and normalize metabolic function. Healthy lifestyle support, such as diet and stress management, is also important to help optimally manage this condition. In conclusion, hypothyroidism is characterized by a decrease in thyroid hormone production and preventive management is pharmacological in the form of levothyroxine, while non-pharmacological management is in the form of regulating food intake.
Chronic Lymphocytic Leukemia: A Literature Review Maulana, Muhammad Rafi; Nurmawaddah, Intan; Ilmiah, Janiya Abdila; Damayanti, Ida Ayu Andara; Wiguna, I Made Danuarta; Anggoro, Joko; Maulana, Akhada
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10078

Abstract

Chronic Lymphocytic Leukemia (CLL) is a slowly progressing hematological cancer characterized by the accumulation of abnormal B lymphocytes in the blood, bone marrow, and lymphatic tissue, commonly affecting the elderly. This review aims to comprehensively review the epidemiology, molecular basis of the disease, clinical symptoms, diagnosis, and therapeutic advances of CLL, emphasizing the importance of shifting treatment approaches towards more precision therapy. A literature search was conducted through PubMed, Scopus, and Web of Science using the keywords "Chronic Lymphocytic Leukemia", "epidemiology", "molecular basis of the disease", and "targeted therapy", with publication criteria between 2018–2025, full text, and topic relevance. Analysis was conducted using a narrative review and thematic synthesis approach to identify epidemiological trends, therapeutic effectiveness, and clinical implications. The results showed that the incidence of CLL is higher in Western countries compared to Asia, with a higher prevalence in elderly men. The main genetic factors that play a role include del(13q), del(17p), and TP53 mutations. Over the past decade, targeted therapies such as second-generation Bruton's tyrosine kinase inhibitors (acalabrutinib, zanubrutinib) and the venetoclax-obinutuzumab combination have been shown to improve remission rates with fewer side effects compared to chemoimmunotherapy. Minimal Residual Disease (MRD) status has become an important marker for determining when therapy can be stopped early. In conclusion, this review underscores the crucial role of biomarkers and MRD in modern CLL management. Future developments include the integration of personalized therapy approaches and translational research to develop more effective and safe treatment strategies.
Pengembangan Komitmen Organisasi Pada Karyawan Lazismu (Lembaga Amil Zakat, Infaq dan Sadaqah Muhammadiyah) Kabupaten Gresik Maulana, Muhammad Rafi; Saleh, Mohammad; Munir, Akhmad
IJABAH Vol. 3 No. 2 (2025): IJABAH
Publisher : UPT Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ijabah.v3i2.5677

Abstract

Organizational commitment is key to the success of Islamic philanthropic institutions that manage public funds based on trust. This study analyzes the condition of organizational commitment and its development strategies among employees of Lazismu Kabupaten Gresik, a zakat institution with a high reputation for accountability and a strong Islamic culture. Using a descriptive qualitative approach through case studies, data was obtained from in-depth interviews, observations, and document analysis, then analyzed using the interactive model of Miles, Huberman, and Saldaña. The results of the study show that the three dimensions of organizational commitment—affective, sustainable, and normative—are formed simultaneously with different drivers. Affective commitment arises from the internalization of spiritual values and the meaning of work as worship, sustainable commitment is influenced by rational considerations such as income stability and career opportunities, while normative commitment is strengthened by a sense of moral and religious responsibility. Lazismu develops employee commitment through the strengthening of spiritual values, a performance-based reward system, employee involvement in decision-making, and the provision of clear career paths. These findings enrich the Three-Component Model of Organizational Commitment with the context of Islamic work ethics, while also confirming the relevance of social exchange theory in faith-based nonprofit organizations. This study provides theoretical contributions and offers a practical model for zakat institutions in designing human resource policies that balance religious values and modern management practices.