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All Journal Jurnal Biologi Tropis
Untari, Lania Pradiva
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Literature Review: Skin Aging in the Ederly Population Salsabila, Baiq Ghefira Rojwani Putri; Hardiant, Excell Defry; Suryani, Elsa Indah; Salsabila, Tsania Zulfa; Savitri, Puti Amelia; Untari, Lania Pradiva; Paradiesta, Andi Frieskha Naurah; Angelita, Puja Rizkina; Adidaifa, Muhammad Fikri; Musyarof, Disa Fadil; Hidayatullah, Audi
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.10032

Abstract

Skin aging is a progressive degenerative process characterized by a decline in the structural and functional capacity of the skin to maintain its protective, regenerative, and homeostatic roles. It is influenced by both intrinsic factors, such as genetics, telomere shortening, mitochondrial dysfunction, hormonal changes, microbiota alterations, and decreased vitamin D production, and extrinsic factors, including ultraviolet radiation, pollution, smoking, oxidative stress, and lifestyle. Clinically, skin aging presents with thinning, dryness, loss of elasticity, fine to deep wrinkles, pigmentary changes, and benign skin lesions. The increasing elderly population, particularly in Indonesia, highlights the growing importance of addressing skin aging due to its impact not only on physical health but also on psychosocial well-being and quality of life. Management strategies include pharmacological approaches such as sunscreens, moisturizers, vitamin D and collagen supplementation, retinoids, and hormone replacement therapy, as well as non-pharmacological interventions including antioxidant-rich nutrition, hydration, allergen avoidance, wound care, dietary restriction, facial massage, and aesthetic procedures like stem cell therapy. Early prevention, timely recognition, and comprehensive management of skin aging are essential to support healthy aging and maintain the quality of life among the elderly.
Hypothyroidism: A Literature Review Hardiant, Excell Defry; Adidaifa, Muhammad Fikri; Salsabila, Tsania Zulfa; Maulana, Muhammad Rafi; Salsabila, Baiq Ghefira Rojwani Putri; Untari, Lania Pradiva; Suryani, Elsa Indah; Paradiesta, Andi Frieskha Naurah; Savitri, Puti Amelia; Rahmat, Basuki
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.10033

Abstract

Hypothyroidism is a condition in which the thyroid gland is unable to produce enough hormones to meet the body's needs. This condition causes a slowed metabolism, which can lead to various symptoms such as fatigue, weight gain, dry skin, hair loss, constipation, cold intolerance, and facial puffiness. Given the widespread impact of hypothyroidism and the potential for serious complications, special attention is needed for early detection, diagnosis, and effective treatment of hypothyroidism. This literature review was conducted using journal review methods and data searches through sources such as PubMed, Google Scholar, and ScienceDirect. The search used the keywords "hypothyroidism," "hypothyroid," "thyroid gland," and "Hashimoto's thyroiditis." The results of the literature review found that the main cause of hypothyroidism is Hashimoto's thyroiditis, an autoimmune disease in which antibodies attack the thyroid gland. Hypothyroidism is diagnosed by examining elevated TSH and decreased free T4 levels, as well as anti-TPO antibody tests to detect Hashimoto's thyroiditis. Treatment for hypothyroidism generally involves administering levothyroxine, a synthetic thyroid hormone, to replace the deficient hormone and normalize metabolic function. Healthy lifestyle support, such as diet and stress management, is also important to help optimally manage this condition. In conclusion, hypothyroidism is characterized by a decrease in thyroid hormone production and preventive management is pharmacological in the form of levothyroxine, while non-pharmacological management is in the form of regulating food intake.
Antibacterial Activity of Sumbawa Forest Honey (Apis dorsata) against Klebsiella pneumoniae ATCC BA1705 Untari, Lania Pradiva; Wardoyo, Eustachius Hagni; Dirja, Bayu Tirta
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10159

Abstract

Klebsiella pneumoniae is an opportunistic bacterium often associated with antibiotic resistance, necessitating the investigation of natural antibacterial alternatives. Honey is recognized for its bioactive ingredients that possess antibacterial properties. This research sought to assess the antibacterial efficacy of Sumbawa forest honey (Apis dorsata) against K. pneumoniae ATCC BA1705 by inhibition zone test. A laboratory experiment was performed using the well diffusion technique. K. pneumoniae suspensions (McFarland 0.5) were injected onto Mueller Hinton Agar. Wells (Ø 6 mm) were filled with 100 µL of honey at concentrations of 25%, 50%, 75%, and 100%. Tetracycline (1 µg/µL) acted as the positive control, while distilled water functioned as the negative control. Plates were incubated at 35±2°C for a duration of 18 to 24 hours. Inhibition zones were quantified using a caliper, and each experiment was conducted in sextuplicate. Data were expressed as mean ± standard deviation. No inhibitory zones were found at 25% and 50% concentrations (0 mm). Antibacterial activity was seen at 75% concentration, yielding a mean diameter of 10.33±SD mm, and raised to 100% concentration, resulting in a mean diameter of 11.33±SD mm. Tetracycline generated a 26 mm inhibitory zone, while distilled water exhibited none (0 mm). The conclusion is Sumbawa forest honey exhibits concentration-dependent antibacterial activity against K. pneumoniae, with moderate inhibition at concentrations ≥75%. Although less effective than tetracycline, these findings support the potential role of honey as a complementary antibacterial agent.
Cerebral Stroke Secondary to Decompression Ilness (DCI): Pathophysiology, Clinical Presentation, Diagnosis, and Management Khairifathiyyah, Khairifathiyyah; Aryasta, Ida Bagus Putra Bayu; Prawira, I Nyoman Dio Yudha; Untari, Lania Pradiva; Pambudi, Balqis Prudena Kurnia; Hunaifi, Ilsa
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10783

Abstract

Decompression illness (DCI) encompasses two major diving-related disorders: decompression sickness (DCS) and arterial gas embolism (AGE). Both conditions are characterized by the formation of gas bubbles that act as the primary mechanism of tissue injury, resulting in overlapping clinical manifestations and similar therapeutic approaches. This study aims to review the pathophysiology, clinical presentation, diagnosis, and management of DCI that presents with stroke-like neurological symptoms. The method used was a literature review approach based on current evidence from recent scientific publications. Findings show that DCS occurs when dissolved inert gases, such as nitrogen, become supersaturated during ascent and form bubbles within tissues and the venous circulation. AGE typically arises from pulmonary barotrauma, allowing trapped gas to enter the pulmonary veins and reach the arterial circulation, with the brain as the most vulnerable target organ. DCI is considered a medical emergency requiring definitive management with hyperbaric oxygen therapy (HBOT). Neurological manifestations of DCI often resemble conventional ischemic stroke but demonstrate distinct clinical and temporal patterns related to pressure changes. Therefore, in addition to recompression therapy, patients may require standard acute stroke management. Prognosis depends heavily on the promptness of diagnosis and treatment, as early intervention is critical to preventing permanent neurological injury.
Co-Authors Adidaifa, Muhammad Fikri Angelita, Puja Rizkina Aryasta, Ida Bagus Putra Bayu Basuki Rahmat Masdi Siduppa Dirja, Bayu Tirta Eustachius Hagni Wardoyo Hardiant, Excell Defry Hidayatullah, Audi Ilsa Hunaifi, Ilsa Khairifathiyyah, Khairifathiyyah Maulana, Muhammad Rafi Musyarof, Disa Fadil Pambudi, Balqis Prudena Kurnia Paradiesta, Andi Frieskha Naurah Prawira, I Nyoman Dio Yudha Salsabila, Baiq Ghefira Rojwani Putri Salsabila, Tsania Zulfa Savitri, Puti Amelia Suryani, Elsa Indah