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All Journal Jurnal Biologi Tropis Mandala of Health : A Scientific Journal
Asriantin, Isna
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Public Health

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Literature Study: Acute Myeloid Leukimia (AML) Pramesti, Evane Dyahayu; Dhevi, Ni Made Saithanya Gitanjali; Hudhori, Syalsa; Salsabila, Ericha Zabrina; Asriantin, Isna; Anggoro, Joko
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10082

Abstract

Leukemia is a cancer that originates from cells that initially develop into blood cells. Leukemia can be classified as acute or chronic, depending on how quickly the disease appears and how it progresses in the body. This literature review aims to determine the treatment for patients with AML depending on the subtype. This literature review used journal review methods and data searches through various sources. The results of the literature study found that Acute Myeloid Leukemia (AML) is divided into six subtypes. AML is caused by clonal transformation of hematopoietic cells through chromosomal abnormalities and gene mutations, with risk factors including exposure to radiation, benzene, smoking, chemotherapy therapy, the development of chronic myeloid neoplasms, aging, and predisposing diseases. Diagnosis of AML involves peripheral blood and bone marrow analysis, immunophenotyping, cytogenetics, molecular cytogenetics, and imaging to detect the presence and characteristics of leukemic cells. Treatment of AML includes induction therapy, consolidation therapy, and response monitoring, with special considerations for the selection of chemotherapy regimens, stem cell transplantation, and transfusion support to manage associated complications. In conclusion, Acute Myeloid Leukemia (AML) is a condition in which myeloblasts undergo excessive proliferation and fail to differentiate into granulocytes. This condition causes the bone marrow to fill with myeloblasts.
Literature Review: Complications and Management of Post Tonsillectomy Patients with Chronic Tonsillitis Suryani, Elsa Indah; Asriantin, Isna; Pramesti, Evane Dyahayu; Hairy, Fathinah Salsabilla
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10246

Abstract

Chronic tonsillitis is a chronic inflammation of the palatine tonsils caused by a viral or bacterial infection, particularly Group A beta-hemolytic Streptococcus pyogenes. Tonsillitis commonly affects children aged 5-12 years and is a major health problem in the ENT-KL field in Indonesia. The prevalence is around 3.8%. Chronic tonsillitis can cause tonsil enlargement, which can interfere with the respiratory tract and lead to complications. This article is based on a literature review, compiling referen ces from several sources, including PubMed, Google Scholar, ScienceDirect, and ResearchGate. The process involved reading the titles, abstracts, and content of the articles to validate the sources used. Chronic tonsillitis is caused by a viral or bacterial infection that causes repeated inflammation of the tonsils, due to poor oral hygiene, allergies, and inadequate treatment. Clinical manifestations include a sore throat, enlarged tonsils, and respiratory distress. Tonsillitis is diagnosed through a history, physical examination, and supporting tests. Management consists of medication with antibiotics and oral hygiene, as well as surgical tonsillectomy if obstruction or recurrent infection occurs. Post-tonsillectomy complications include bleeding and infection, which must be treated promptly. Both medical and surgical therapy are effective in treating tonsillitis. During tonsillectomy, several factors must be monitored, including post-operative bleeding and infection. Prevention includes maintaining good hygiene and a healthy lifestyle.
SCORING SYSTEM APPLICATION IN MANAGEMENT CHOICES AND PROGNOSIS OF THE PROCEDURE IN PATIENT WITH RISK OF AIRWAY OBSTRUCTION: ARTICLE REVIEW Asriantin, Isna; Suryantarini, Ni Wayan Puspa Wijaya
Mandala Of Health Vol 18 No 2 (2025): Mandala of Health: A Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2025.18.2.17680

Abstract

Airway obstruction is a life-threatening condition that requires prompt recognition and management to prevent morbidity and mortality. Intubation remains the gold standard for securing the airway; however, failed attempts are common and may delay other life-saving interventions. To improve decision-making in selecting appropriate procedures and predicting outcomes, various scoring systems have been developed. This article aims to review the application of scoring systems in management choices and prognosis of patients with risk of airway obstruction. This study employed a systematic literature review by searching PubMed, ScienceDirect, and ProQuest databases using the keywords “scoring system,” “airway obstruction,” “difficulty,” and “management prediction.” Eligible studies included original research and case reports published in English or Indonesian between 2020 and 2025, with complete full-text availability. Eight relevant articles were identified and analyzed. The findings suggest that proper application of validated scoring systems may reduce the incidence of failed intubation, guide elective tracheostomy decisions, and improve prognosis in patients at risk of airway obstruction. Nevertheless, inappropriate or excessive use may lead to unnecessary procedures and complications. Further research is needed to validate these tools across diverse populations and to develop simplified scoring models with higher sensitivity and specificity.
Co-Authors Anggoro, Joko Dhevi, Ni Made Saithanya Gitanjali Hairy, Fathinah Salsabilla Hudhori, Syalsa Pramesti, Evane Dyahayu Salsabila, Ericha Zabrina Suryani, Elsa Indah Suryantarini, Ni Wayan Puspa Wijaya