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Literature Study: Acute Myeloid Leukimia (AML) Pramesti, Evane Dyahayu; Dhevi, Ni Made Saithanya Gitanjali; Hudhori, Syalsa; Salsabila, Ericha Zabrina; Asriantin, Isna; Anggoro, Joko
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10082

Abstract

Leukemia is a cancer that originates from cells that initially develop into blood cells. Leukemia can be classified as acute or chronic, depending on how quickly the disease appears and how it progresses in the body. This literature review aims to determine the treatment for patients with AML depending on the subtype. This literature review used journal review methods and data searches through various sources. The results of the literature study found that Acute Myeloid Leukemia (AML) is divided into six subtypes. AML is caused by clonal transformation of hematopoietic cells through chromosomal abnormalities and gene mutations, with risk factors including exposure to radiation, benzene, smoking, chemotherapy therapy, the development of chronic myeloid neoplasms, aging, and predisposing diseases. Diagnosis of AML involves peripheral blood and bone marrow analysis, immunophenotyping, cytogenetics, molecular cytogenetics, and imaging to detect the presence and characteristics of leukemic cells. Treatment of AML includes induction therapy, consolidation therapy, and response monitoring, with special considerations for the selection of chemotherapy regimens, stem cell transplantation, and transfusion support to manage associated complications. In conclusion, Acute Myeloid Leukemia (AML) is a condition in which myeloblasts undergo excessive proliferation and fail to differentiate into granulocytes. This condition causes the bone marrow to fill with myeloblasts.
Literature Review: Complications and Management of Post Tonsillectomy Patients with Chronic Tonsillitis Suryani, Elsa Indah; Asriantin, Isna; Pramesti, Evane Dyahayu; Hairy, Fathinah Salsabilla
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10246

Abstract

Chronic tonsillitis is a chronic inflammation of the palatine tonsils caused by a viral or bacterial infection, particularly Group A beta-hemolytic Streptococcus pyogenes. Tonsillitis commonly affects children aged 5-12 years and is a major health problem in the ENT-KL field in Indonesia. The prevalence is around 3.8%. Chronic tonsillitis can cause tonsil enlargement, which can interfere with the respiratory tract and lead to complications. This article is based on a literature review, compiling referen ces from several sources, including PubMed, Google Scholar, ScienceDirect, and ResearchGate. The process involved reading the titles, abstracts, and content of the articles to validate the sources used. Chronic tonsillitis is caused by a viral or bacterial infection that causes repeated inflammation of the tonsils, due to poor oral hygiene, allergies, and inadequate treatment. Clinical manifestations include a sore throat, enlarged tonsils, and respiratory distress. Tonsillitis is diagnosed through a history, physical examination, and supporting tests. Management consists of medication with antibiotics and oral hygiene, as well as surgical tonsillectomy if obstruction or recurrent infection occurs. Post-tonsillectomy complications include bleeding and infection, which must be treated promptly. Both medical and surgical therapy are effective in treating tonsillitis. During tonsillectomy, several factors must be monitored, including post-operative bleeding and infection. Prevention includes maintaining good hygiene and a healthy lifestyle.
Giant Cell Tumor of Bone, Tendon, and Soft Tissue: Pathogenesis and Clinical Manifestations Yulianti, Arwinda Febri; Paerdoe, Lalu Dane Pemban; Hidayat, Rahmat; Qindi, Ahmad Sa`bi Al; Hadinata, Lalu Gde Gilang Alid; Widad, Najwa; Febianisa, Tabitha Afifah; Pramesti, Evane Dyahayu; Khairifathiyyah, Khairifathiyyah; Amalia, Azka; Purnaning, Dyah
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10350

Abstract

Giant Cell Tumor (GCT) is a primary neoplasm that is intermediate malignant, characterized by aggressive local growth and the possibility of metastasis, especially to the lungs. Giant Cell Tumor (GCT) occurs in bones, tendons, and soft tissues. The purpose of this literature study is to identify differences in GCT manifestations in various anatomical locations, evaluate risk factors that contribute to tumor growth and recurrence, and assess the effectiveness of various therapeutic modalities that have been used, both conservative and operative. The method used is a literature study by reviewing various scientific journals obtained from the database. The findings show that Giant Cell Tumor (GCT) is a group of neoplasms that are histologically similar but have different clinical, molecular characteristics, and anatomical locations, including GCT in bones (GCTB), tendons (GCTTS), and soft tissues (GCTST). Although generally classified as benign, GCT can be locally aggressive with a risk of recurrence and in some cases is capable of metastasis, especially to the lungs. GCTB is most commonly found in the long bones of individuals aged 20–40 years and is characterized by the H3F3A mutation, which is an important diagnostic marker. GCTTS, which originates in the synovium, is more common in women aged 30–50 years and shows increased CSF1 expression due to a genetic translocation.
Pelatihan Kader Posyandu untuk Pendampingan Korban Kekerasan Seksual di Kelurahan Banjar Kecamatan Ampenan Kota Mataram Pujiarohman, Pujiarohman; Herlina, Lenny; Syamsun, Arfi; Harahap, Ida Lestari; Pramesti, Evane Dyahayu; Wahid, Lalu Abdurrachman
Al-DYAS Vol 4 No 2 (2025): JUNI
Publisher : Lembaga Yasin AlSys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/aldyas.v4i2.6121

Abstract

Sexual violence in Indonesia has increased significantly, both in terms of quantity and quality. Through a report from the Ministry of Women's Empowerment and Child Protection (KemenPPPA), more than 9,600 cases of violence against children were recorded in the period from January to May 2023. This increasing trend is largely due to the increasing courage of victims to report the incident. The main focus of this case is sexual violence, which includes rape, molestation, and sexual exploitation. West Nusa Tenggara (NTB), as an example, recorded 188 cases of sexual violence against children in 2021-2022, with types of incidents including rape and molestation. Involving various impacts, sexual violence damages the physical, emotional, and psychological aspects of the victim. Serious handling and in-depth understanding from various sectors are key to overcoming this problem. The involvement of Posyandu as a public health institution is a proactive solution to provide support and assistance to victims of sexual violence. Through training of Posyandu cadres in Banjar Village, Ampenan District, it is hoped that a responsive support network can be formed to address the issue of sexual violence at the community level. Collaboration with health, child protection, and mental health institutions is an integrated step that supports victim recovery. This service contributes to the understanding of the importance of the role of Posyandu in dealing with sexual violence and details the impacts and concrete solutions to improve prevention and recovery. The conclusions of this study provide a deeper understanding of the complexity of the issue of sexual violence and provide a basis for policy recommendations to improve the community approach in addressing this problem.