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All Journal Andalas obstetrics and gynecology journal Paradigma: Jurnal Filsafat, Sains, Teknologi, dan Sosial Budaya
Asyifa Delfilaura
Unknown Affiliation
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Immunology & microbiology Languange, Linguistic, Communication & Media Nursing Public Health Social Sciences

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Gambaran Kadar Hemoglobin pada Remaja Putri; Studi Kasus di SMP Negeri 27 Padang Burhan, Ida Rahmah; Firdawati, Firdawati; Asy Syukri, Muhammad Hasbi; Fauziah Nur; Fikri Rahman; Putri, Rizqy Nurfathonah; Asyifa Delfilaura; Rahadi, Didan Ariadapa; Dharma, Fitri Yeni
Andalas Obstetrics And Gynecology Journal Vol. 9 No. 1 (2025)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.9.1.105-114.2025

Abstract

Introduction: The prevalence of anemia in adolescent girls worldwide is reported to be around 40-88%. Adolescent girls with anemia can affect work productivity or academic ability at school due to a lack of enthusiasm for learning and focus. Anemia in adolescent girls can continue throughout their lives and put them at risk of becoming anemic pregnant women who can give birth to premature babies and leading to stunting. This study aims to determine the description of hemoglobin levels in female adolescents at SMP Negeri 27 Padang. Method: The research was descriptive, using a sample of 116 adolescent girls selected by proportionate stratified random sampling. Hemoglobin levels were examined using the Point of Care Testing (POCT) method using capillary blood. Results: The results show that most hemoglobin levels are normal, namely 60 respondents (51,7%), low hemoglobin levels are 55 respondents (47,4%), and high hemoglobin levels are 1 respondents (0,9%). Conclusion: It can be concluded that hemoglobin levels among adolescent girls at SMP Negeri 27 Padang generally have normal hemoglobin levels. Keywords: Adolescent girls, anemia, hemoglobin
Protective Effect of Momordica charantia on Intestinal Histopathology in Mice Infected with Salmonella typhi: A Post test Randomazide Controlled Study Nisriinaa Yurensi; Wahida Rahmi; Asyifa Delfilaura; Tofrizal
Paradigma: Jurnal Filsafat, Sains, Teknologi, dan Sosial Budaya Vol. 32 No. 2 (2026): Paradigma: Jurnal Filsafat, Sains, Teknologi, dan Sosial Budaya
Publisher : Universitas Insan Budi Utomo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33503/paradigma.v32i2.3966

Abstract

The effect of Momordica charantia on intestinal histopathology in Salmonella typhi-infected mice remains unclear. This study aimed to evaluate histological changes in the small intestine following administration of M. charantia juice at graded doses. Twenty paraffin-embedded ileum samples from previously infected mice were divided into four groups: infected untreated control (K), and three treatment groups receiving 50 g (P1), 100 g (P2), and 200 g (P3) of bitter melon juice. Histological assessment included measurements of mucosa, villi, crypts, and muscle layer thickness, as well as inflammation scoring using the Barthel Mandja system. The 100 g dose (P2) yielded the greatest improvement in mucosal and villous height and showed a complete shift from severe to moderate inflammation. Crypt depth was significantly different among groups (p = 0.001), with P2 showing the most normalized architecture. However, mucosa, villi, and muscle layers showed no statistically significant differences. These findings suggest that M. charantia at a 100 g dose offers optimal protection of intestinal architecture and reduces inflammatory severity in S. typhi-infected mice. Higher doses may reduce efficacy, highlighting the need for dose optimization.
Co-Authors Asy Syukri, Muhammad Hasbi Dharma, Fitri Yeni Fauziah Nur Fikri Rahman Firdawati Firdawati Ida Rahmah Burhan Nisriinaa Yurensi Putri, Rizqy Nurfathonah Rahadi, Didan Ariadapa Tofrizal Wahida Rahmi