Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Public Health of Indonesia Journal of Fundamental and Applied Pharmaceutical Science
Zilhadia
Unknown Affiliation
Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Analysis of the Entrapment Efficiency of Thymoquinone in Microcapsules of Black Cumin Seed Oil (Nigella sativa L.) Using High Performance Liquid Chromatography Ofa Suzanti Betha; Supandi, Supandi; Addina Syahida; Boy Reynaldi Noor; Nelly Suryani; Sabrina Dahlizar; Yuni Anggraeni; Barita J. Siregar; Zilhadia
Journal of Fundamental and Applied Pharmaceutical Science Vol. 6 No. 1 (2025): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v6i1.27545

Abstract

Thymoquinone is the main active compound found in black cumin seed oil (Nigella sativa). This study intends to analyze the efficiency of its absorption in microcapsules by the ionic gelation of cross-linked alginate and the CaCl2 method, and loading with black cumin seed oil in a concentration of 20%. Thymoquinone was used as a marker to establish quality standards for this microcapsule preparation. Analysis of thymoquinone in microcapsules was performed using a pre-optimized, high-performance liquid chromatography method. Method optimization utilized an Acclaim® Polar Advantage II (C18) column with a flow speed of 1.5 mL/min, a UV detector wavelength of 252 nm, and an injection volume of 20 μL with an isocratic system on a methanol eluent composition: water (70:30). This method revealed a good linearity value (r = 0.9997) in the range of 0.5 – 500 μg/ml. The detection and quantitation limits were 8.67 μg/mL and 28.9 μg/mL, (%diff) was about -1.864 to 1.562, precision (% RSD) was 0.052 to 0.113%, and the recovery was 98.135 to 101.563%. The results of this method validation were then applied to determine thymoquinone loading in black cumin seed oil microcapsules. The results of the absorption efficiency value of black cumin seed oil microcapsules by the ionic gelation alginate and CaCl2 method, which contained 20% oil concentration in the formula, were 81.769%.
Knowledge, Attitude, and Practice Regarding Iron Deficiency Anemia Prevention Among Female Adolescents in Bogor City, Indonesia Wardani, Riastuti Kusuma; Nurmansyah, Muhammad Iqbal; Yustiyani; Iriani, Dewi Utami; Ariyanti, Fajar; Zilhadia; Kilic, Bulent
Public Health of Indonesia Vol. 12 No. 1 (2026): January - March
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v12i1.1276

Abstract

Background: Iron deficiency anemia (IDA) is a significant public health issue due to its prevalence and numerous contributing factors, specifically among female adolescents. Objective: The study aimed to examine the influence of knowledge and attitude on IDA prevention practice among female adolescents in Bogor City, Indonesia. Methods: This cross-sectional study was carried out among 20 junior high schools in Bogor City, Indonesia. A total of 1.410 female students were selected through a non-probability sampling method. The Spearman rank correlation test was then used to examine the relationship between knowledge, attitude, and practice regarding IDA prevention. Results: The results showed that the average scores for knowledge, attitude, and practice were 5.92 (out of 15), 11.56 (out of 15), and 8.95 (out of 12), respectively. In addition, knowledge had a significant correlation with attitude (p-value = 0.001, r = 0.185), and attitude showed a significant correlation with practice (p-value = 0.005, r = 0.075). Conclusion: The limited understanding of female students concerning IDA may influence their attitude and practice towards its prevention. This indicates that the implementation of diverse strategies is essential to enhance understanding of anemia, thereby improving prevention behavior. Keyword: Anemia, Chronic Diseases, Developing Countries, Female Student, School-Based
Co-Authors Addina Syahida Ariyanti, Fajar Barita J. Siregar Boy Reynaldi Noor Iriani, Dewi Utami Kilic, Bulent Nelly Suryani Nurmansyah, Muhammad Iqbal Ofa Suzanti Betha Riastuti Kusuma Wardani Supandi Yuni Anggraeni Yustiyani