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Aplastic Anemia: A literature Review Maringka, Kezia Michella Yusak; Lestarini, Ima Arum
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7695

Abstract

Aplastic anemia (AA) is a rare but serious hematologic disorder characterized by bone marrow failure, leading to pancytopenia and a reduction in all blood cell lines. This study aims to explore the definition, etiology, pathophysiology, diagnosis, and treatment of AA. A comprehensive literature review was conducted using electronic databases such as PubMed, ProQuest, ScienceDirect, MDPI, and Google Scholar, focusing on studies and reviews related to AA. The findings indicate that the primary causes of AA include immune-mediated destruction of hematopoietic stem cells, with potential triggers such as drugs, chemicals, and autoimmune disorders. The diagnosis is confirmed through clinical evaluation, blood tests, and bone marrow biopsy. Treatment strategies consist of immunosuppressive therapy, hematopoietic stem cell transplantation (HSCT), and supportive care. In conclusion, early diagnosis and appropriate treatment are essential for improving the prognosis of patients with AA.
EDUKASI POLA MAKAN SEHAT DAN AKTIVITAS FISIK MENGGUNAKAN BOARD GAME DI PANTI ASUHAN DHARMA LAKSANA KOTA MATARAM Sari, Dian Puspita; Abdiman, I Made Tobias; Maringka, Kezia Michella Yusak; Manafe, Winda; Patandianan, Firdaus Kamma
Jurnal Abdi Insani Vol 11 No 3 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i3.1898

Abstract

The prevalence of obesity among children and adolescents is rising globally, leading to short- and long-term health issues such as type 2 diabetes (Type 2 DM). While obesity has multiple causes, modifiable lifestyle factors like diet and physical activity can reduce the risk Indonesian children are exposed to high-sugar, low-nutrient foods and engage in limited physical activity, increasing their risk for obesity and Type 2 DM. Although children depend on adults for food, they must learn to make healthy choices early on. This community service activity aimed to improve knowledge and promote healthy eating and physical activity among foster children at the Dharma Laksana Orphanage in Mataram City. A brief survey found that 33-60% of the children chose high-sugar foods over healthier options. Education was delivered through presentations and a custom-developed board game, "Pilah Pilih" (Select and Choose), which included a storybook and guide. Forty children and two caregivers participated. Post-activity evaluations showed 60% of children scored above 70 in knowledge assessments, with a highest score of 85. Feedback on the game indicated positive engagement and enthusiasm for replay. The "Pilah Pilih" board game shows potential as an effective educational tool to encourage behavioral change through repeated play.