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All Journal Jurnal Biologi Tropis Jurnal Abdi Insani Cardiovascular and Cardiometabolic Journal (CCJ)
Maringka, Kezia Michella Yusak
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Aplastic Anemia: A literature Review Maringka, Kezia Michella Yusak; Lestarini, Ima Arum
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7695

Abstract

Aplastic anemia (AA) is a rare but serious hematologic disorder characterized by bone marrow failure, leading to pancytopenia and a reduction in all blood cell lines. This study aims to explore the definition, etiology, pathophysiology, diagnosis, and treatment of AA. A comprehensive literature review was conducted using electronic databases such as PubMed, ProQuest, ScienceDirect, MDPI, and Google Scholar, focusing on studies and reviews related to AA. The findings indicate that the primary causes of AA include immune-mediated destruction of hematopoietic stem cells, with potential triggers such as drugs, chemicals, and autoimmune disorders. The diagnosis is confirmed through clinical evaluation, blood tests, and bone marrow biopsy. Treatment strategies consist of immunosuppressive therapy, hematopoietic stem cell transplantation (HSCT), and supportive care. In conclusion, early diagnosis and appropriate treatment are essential for improving the prognosis of patients with AA.
EDUKASI POLA MAKAN SEHAT DAN AKTIVITAS FISIK MENGGUNAKAN BOARD GAME DI PANTI ASUHAN DHARMA LAKSANA KOTA MATARAM Sari, Dian Puspita; Abdiman, I Made Tobias; Maringka, Kezia Michella Yusak; Manafe, Winda; Patandianan, Firdaus Kamma
Jurnal Abdi Insani Vol 11 No 3 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i3.1898

Abstract

The prevalence of obesity among children and adolescents is rising globally, leading to short- and long-term health issues such as type 2 diabetes (Type 2 DM). While obesity has multiple causes, modifiable lifestyle factors like diet and physical activity can reduce the risk Indonesian children are exposed to high-sugar, low-nutrient foods and engage in limited physical activity, increasing their risk for obesity and Type 2 DM. Although children depend on adults for food, they must learn to make healthy choices early on. This community service activity aimed to improve knowledge and promote healthy eating and physical activity among foster children at the Dharma Laksana Orphanage in Mataram City. A brief survey found that 33-60% of the children chose high-sugar foods over healthier options. Education was delivered through presentations and a custom-developed board game, "Pilah Pilih" (Select and Choose), which included a storybook and guide. Forty children and two caregivers participated. Post-activity evaluations showed 60% of children scored above 70 in knowledge assessments, with a highest score of 85. Feedback on the game indicated positive engagement and enthusiasm for replay. The "Pilah Pilih" board game shows potential as an effective educational tool to encourage behavioral change through repeated play.
The Correlation Between Active Smoking Behaviour and SYNTAX Score on Male Patients with Coronary Artery Disease Maringka, Kezia Michella Yusak; Ermawan, Romi; Sari, Dian Puspita; Rahmat, Basuki
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 7 No. 1 (2026): Cardiovascular and Cardiometabolic Journal - In Press
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v7i1.2026.1-11

Abstract

Background: This study aimed to determine the relationship between smoking behavior and SYNTAX score in male patients with coronary artery disease (CAD) at the Regional General Hospital of NTB Province. Material and Methods: This observational analytic study used a cross-sectional approach, conducted from August to November 2023 in the cath lab of NTB Provincial General Hospital. A total of 94 male CAD patients diagnosed through coronary angiography were enrolled, divided into smokers and non-smokers. Medical records were reviewed, and SYNTAX scores were calculated using angiography data under the supervision of a consultant cardiologist. The study used consecutive sampling to select eligible patients based on the inclusion and exclusion criteria. Data were analyzed using independent t-tests and ANCOVA. Results: Among the 94 patients in this study, 48.9% had a history of hypertension, 25.5% had DM, and 31.9% had dyslipidemia. The mean age was 57.9 years with a standard deviation of 9.7. The body mass index (BMI) ranged from 18.4 to 34.8, with 39.4% in the normal BMI category. Regarding therapy history, 2.1% had received statin and antiplatelet therapy before angiography. SYNTAX score distribution showed that 57.4% had a low SYNTAX score, 23% had an intermediate score, and 17% had a high score, with a mean of 20.7 ± 11.9. After adjusting for confounding variables, a significant association was found between smoking behavior and SYNTAX score (p = 0.046; mean difference = 4.8). Conclusion: There is a significant difference in SYNTAX score between male CAD patients with smoking behavior and without smoking behavior. Smoking behavior is significantly associated with higher SYNTAX scores. Smoking cessation interventions may help reduce the complexity of CAD. Further research is needed to evaluate the impact of smoking cessation on SYNTAX scores in this population. -- Highlights: 1. This study demonstrates that smoking is linked to more severe and complex coronary artery disease, as reflected by higher angiographic severity scores in male patients. 2. Even after accounting for major cardiovascular risk factors, smoking remains an independent contributor to disease burden, reinforcing its critical role in worsening coronary pathology.
Co-Authors Abdiman, I Made Tobias Basuki Rahmat Masdi Siduppa Dian Puspita Sari Ima Arum Lestarini Manafe, Winda Patandianan, Firdaus Kamma Romi Ermawan, Romi