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All Journal Jurnal Biologi Tropis Indonesian Journal of Health and Medical Education
Mussyafa, Aulia Putri
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Characteristics and Therapeutic Patterns of Hyperthyroidism in Eastern Indonesia: A Hospital-Based Study Rahmatullah, Alif Rizki; Fadhila, Luthfiya Nur; Mussyafa, Aulia Putri; Wulandari, Inayah; Tunairin, Siti Raodatul Jannah; Gunawan, Aulya Khalisha; Nurmawaddah, Intan; Ningrum, Sania Tresna; Rahadian A., M. Fathir; Kusuma P, I Putu Aryana; Rifki, Muhammad
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10431

Abstract

Hyperthyroidism, a condition of excessive thyroid hormone production, presents significant diagnostic and management challenges worldwide. Its clinical spectrum is broad, influenced by etiology, patient demographics, and regional factors. This study was conducted to provide a detailed description of the clinical characteristics, demographic profile, and management patterns of hyperthyroid patients at Dr. (H.C) Ir. Soekarno Regional General Hospital, a tertiary care center in Bangka Belitung Province. This research utilized a descriptive observational method with a cross-sectional design. Data were retrospectively collected from the medical records of 83 patients diagnosed with hyperthyroidism between January and December 2024. The collected variables included age, gender, clinical manifestations, laboratory findings, and prescribed therapeutic regimens. The analysis revealed a significant female predominance (86.7%) among patients, with the majority falling into the >35 years age group (56.6%), confirming established epidemiological trends. The most prevalent clinical findings were palpitations (90.4%), goiter (85.5%), and unexplained weight loss (78.3%). Graves' disease was identified as the primary etiology in 72.3% of cases. The mainstay of treatment was pharmacotherapy, with Methimazole being the most frequently prescribed antithyroid drug (81.9%), often supplemented with beta-blockers (74.7%) for symptomatic control. This study concludes that the clinical profile of hyperthyroidism at this tertiary hospital aligns with classical presentations, predominantly affecting adult women. The findings underscore the importance of recognizing key symptoms for early diagnosis and affirm that current management practices are consistent with established clinical guidelines.
ANATOMICAL VARIATIONS AND THERAPEUTIC APPROACHES OF CHOLEDOCHAL CYSTS Shiddiq, Muhammad Hilmy As; Putri, Imey Pinasty Harianto; Fadhila, Luthfiya Nur; Ansary, Muhammad Fathir Rahadian; Mussyafa, Aulia Putri; Indratama, I Nyoman Yudayana; Tunairin, Siti Raodatul Jannah; Rifki, Muhammad; Zuhan, Arif
Indonesian Journal of Health and Medical Education Vol. 1 No. 1 (2026): Edisi Januari-Juni 2026
Publisher : Indonesian Publication Center

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Abstract

Choledochal cysts are congenital anomalies characterized by abnormal dilatation of the bile ducts, either intrahepatic or extrahepatic. This condition can lead to serious complications, including cholangitis, pancreatitis, and malignancy. Choledochal cysts are more prevalent in Asian populations compared to Western populations and are more commonly observed in females. Timely diagnosis is crucial to prevent further complications. This study aims to conduct a literature review on the anatomical variations and available therapeutic methods for managing choledochal cysts, as well as to evaluate the effectiveness of various treatment approaches. A systematic literature review methodology was employed, involving database identification, keyword selection, article screening, and the use of recent publications from reputable scientific databases such as PubMed, Google Scholar, and Scopus. This review identifies five types of choledochal cysts based on the Todani classification, with Type I being the most common. The primary treatment for choledochal cysts involves complete cyst excision, usually followed by biliary reconstruction using Roux-en-Y hepaticojejunostomy. In more advanced cases, complex surgical procedures such as pancreaticoduodenectomy may be required. Biliary reconstruction following cyst excision, particularly through Roux-en-Y jejunostomy, has been proven effective and is considered the gold standard in choledochal cyst management. Surgical approaches should be tailored to the cyst type to achieve optimal clinical outcomes.
Co-Authors Ansary, Muhammad Fathir Rahadian Fadhila, Luthfiya Nur Gunawan, Aulya Khalisha Indratama, I Nyoman Yudayana Kusuma P, I Putu Aryana Muhammad Rifki Ningrum, Sania Tresna Nurmawaddah, Intan Putri, Imey Pinasty Harianto Rahadian A., M. Fathir Rahmatullah, Alif Rizki Shiddiq, Muhammad Hilmy As Tunairin, Siti Raodatul Jannah Wulandari, Inayah Zuhan, Arif