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All Journal Jurnal Biologi Tropis Indonesian Journal of STEM Education Indonesian Journal of Elementary and Childhood Education Indonesian Journal of Applied Science and Technology Indonesian Journal of Health and Medical Education
As Shiddiq, Muhammad Hilmy
Faculty Of Medicine And Health Sciences, University Of Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Understanding Precocious Puberty: When Childhood Ends Too Soon Muliana, Atriska Citra; Putri, Imey Pinasty Harianto; Prasetya, Rangga Cahya; Indratama, I Nyoman Yudayana; Athalia, Ihza Namira; Shafitri, Shira Shalsabina; Mertasari, Baiq Merna; Josafat, Gantha Narendra; Ilmiah, Janiya Abdila; As Shiddiq, Muhammad Hilmy; Aulia, Rashieka Salma; Ajmala, Indana Eva
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10337

Abstract

Precocious puberty is an endocrine disorder characterized by the premature development of secondary sexual characteristics, defined as occurring before the age of 8 in girls and 9 in boys. This literature review aims to understand precocious puberty: when childhood ends too soon. The article was compiled using a literature review method. Data were obtained through a search of various scientific sources, including international and national journals, textbooks, and clinical guidelines from the Indonesian Pediatrician Association (IDAI). Central precocious puberty, most often idiopathic in girls but associated with underlying pathology in boys, is caused by premature activation of the hypothalamic-pituitary-gonadal axis, while the peripheral form is caused by excess sex steroid production independent of gonadotropin stimulation. Clinical manifestations include early breast development, testicular enlargement, rapid linear growth, acne, and the early appearance of pubic or axillary hair. Diagnosis relies on a combination of careful history taking, physical examination, hormonal testing, bone age assessment, and imaging studies such as pelvic ultrasound or cranial MRI when indicated. Management strategies vary based on etiology, with gonadotropin-releasing hormone (GnRH) agonists being the standard treatment for central precocious puberty, while surgical or medical therapy is used for peripheral causes. In conclusion, precocious puberty is a childhood health issue of increasing concern due to its increasing global incidence. This condition not only impacts accelerated bone maturation and potential short stature in adulthood, but also impacts the child's psychological well-being and causes emotional distress to the family.
Case Study of Bilateral Ureteral Stones Complicated by Acute Kidney Injury in a 52-Year-Old Female Patient Ilmiah, Janiya Abdila; Putri, Imey Pinasty Harianto; Muliana, Atriska Citra; Athalia, Ihza Namira; Shafitri, Shira Shalsabina; Sari, Baiq Merna Merta; Aulia, Rashieka Salma; Prasetya, Rangga Cahya; Indratama, I Nyoman Yudayana; Shiddiq, Muhammad Hilmy As; Josafat, Gantha Narendra
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10344

Abstract

Bilateral ureteral stones are a rare clinical manifestation of renal colic, obstructing urine flow, and can cause severe acute kidney injury (AKI) within hours. This case study aims to provide information regarding the diagnosis and management of bilateral ureteral stones causing acute kidney injury in a 52-year-old female patient. This case study uses a descriptive method to describe the current situation, for further analysis and interpretation. Based on anamnesis and physical examination, the patient was diagnosed with Acute Kidney Injury (AKI) stage 3 with a differential diagnosis of Advanced Chronic Kidney Disease (ACKD) stage 4. This condition is caused by urinary tract obstruction due to bilateral ureterolithiasis (stones in both ureters) and proximal right ureteral stenosis, which inhibits urine flow and worsens kidney function acutely and chronically. Complaints of right and left abdominal pain, as well as a history of urinary tract infections (UTIs) and hypertension, support the formation of stones in the urinary tract. The conclusion is that the patient Wirni/P/52 years old/AKI stage 3 dd ACKD stage 4 dt obstructive uropathy + ureterolithiasis infection + normocytic normochromic anemia dt chronic disease + bilateral ureteral stones + right proximal ureteral stenosis.
Factors Associated with Compliance to Iron Supplementation Tablet Consumption Among Adolescent Girls in Coastal Area of West Lombok As Shiddiq, Muhammad Hilmy; Lestarini, Ima Arum; Restuningdyah, Novia Andansari Putri
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10188

Abstract

Anemia remains a major health problem among adolescent girls in Indonesia, with significant implications for reproductive health and productivity. Since 2014, the government has implemented an iron supplementation program through schools, yet compliance remains low. This study aimed to analyze the relationship between family support, teacher support, peer support, and socioeconomic status with compliance to iron tablet consumption among adolescent girls at SMAN 1 Lembar. This was an analytical observational study with a cross-sectional design. A total of 84 students were selected using purposive sampling. Data were collected through a validated and reliable online questionnaire and analyzed using the Chi-Square test. The results showed significant associations between teacher support (p<0.05) and peer support (p<0.05) with compliance to iron tablet consumption, while family support and socioeconomic status showed no significant associations (p>0.05). In conclusion, compliance with iron tablet consumption among adolescent girls is more strongly influenced by teacher and peer support than by family or socioeconomic factors. Strengthening school involvement and peer influence may serve as effective strategies to improve adherence and enhance anemia prevention programs.
Development Trends of E-Modules in Science Education for Fostering 21st-Century Skills: A Narrative Review Gunawan, Gunawan; Herayanti, Lovy; Shiddiq, Muhammad Hilmy As
Indonesian Journal of STEM Education Vol. 8 No. 1 (2026): Edisi Januari-Juni 2026 (Continuous Publication)
Publisher : Indonesian Publication Center

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Abstract

The post-pandemic integration of technology in education has accelerated the transformation of teaching materials from print to digital formats. This study aims to provide a narrative review of current trends in the development of electronic modules (E-Modules) in science education, specifically focusing on fostering 21st-century skills. By analyzing recent literature (2021–2025), this review identifies a shift from mere content digitalization to the creation of complex interactive media. Key findings indicate that: (1) Current E-Module development is dominated by the integration of active pedagogical models, particularly Problem-Based Learning (PBL) and STEM (Science, Technology, Engineering, and Mathematics) approaches; (2) There is a distinctive trend of merging digital technology with local wisdom (Ethnoscience) to enhance learning relevance; and (3) The primary learning outcomes targeted are critical thinking, science literacy, and problem-solving skills. This review concludes that modern E-Modules no longer function solely as passive reading resources but as interactive learning environments that effectively bridge scientific conceptual understanding with future competency demands.
Innovations in Elementary School Health Promotion Programs: An Integrative Review Muhammad Hilmy As Shiddiq; Gunawan Gunawan; Hamsu Kadriyan; Baik Nilawati Astini; Ni Made Yeni Suranti
Indonesian Journal of Elementary and Childhood Education Vol. 6 No. 4 (2025): Edisi Desember 2025
Publisher : Indonesian Publication Center

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Abstract

Elementary schools represent a strategic setting for instilling healthy behaviors early in life, as children are in a critical period of habit and character formation. Along with the evolution of educational practices, conventional health education methods have shifted toward more interactive, participatory, and holistic approaches. This study aims to explore and synthesize recent innovations and strategies in implementing health programs in elementary schools. An integrative review design was applied by analyzing 44 selected articles, including quantitative, qualitative, and experimental studies. The reviewed literature focuses on interventions related to physical health, mental health, and dental health among elementary school students. The findings identify four main clusters of program innovation: the use of creative media and gamification to enhance health knowledge, classroom-based mental health interventions such as deep breathing and mindfulness, the integration of physical education to address obesity prevention and character development, and comprehensive school health management that emphasizes the role of teachers and supportive school policies. The review concludes that health programs in elementary schools are shifting from one-way counseling toward more engaging and participatory interventions, with multidimensional approaches demonstrating greater effectiveness in improving student health outcomes.
ANATOMICAL VARIATIONS AND THERAPEUTIC APPROACHES OF CHOLEDOCHAL CYSTS Shiddiq, Muhammad Hilmy As; Putri, Imey Pinasty Harianto; Fadhila, Luthfiya Nur; Ansary, Muhammad Fathir Rahadian; Mussyafa, Aulia Putri; Indratama, I Nyoman Yudayana; Tunairin, Siti Raodatul Jannah; Rifki, Muhammad; Zuhan, Arif
Indonesian Journal of Health and Medical Education Vol. 1 No. 1 (2026): Edisi Januari-Juni 2026
Publisher : Indonesian Publication Center

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Abstract

Choledochal cysts are congenital anomalies characterized by abnormal dilatation of the bile ducts, either intrahepatic or extrahepatic. This condition can lead to serious complications, including cholangitis, pancreatitis, and malignancy. Choledochal cysts are more prevalent in Asian populations compared to Western populations and are more commonly observed in females. Timely diagnosis is crucial to prevent further complications. This study aims to conduct a literature review on the anatomical variations and available therapeutic methods for managing choledochal cysts, as well as to evaluate the effectiveness of various treatment approaches. A systematic literature review methodology was employed, involving database identification, keyword selection, article screening, and the use of recent publications from reputable scientific databases such as PubMed, Google Scholar, and Scopus. This review identifies five types of choledochal cysts based on the Todani classification, with Type I being the most common. The primary treatment for choledochal cysts involves complete cyst excision, usually followed by biliary reconstruction using Roux-en-Y hepaticojejunostomy. In more advanced cases, complex surgical procedures such as pancreaticoduodenectomy may be required. Biliary reconstruction following cyst excision, particularly through Roux-en-Y jejunostomy, has been proven effective and is considered the gold standard in choledochal cyst management. Surgical approaches should be tailored to the cyst type to achieve optimal clinical outcomes.
PROGNOSTIC FACTORS IN PEDIATRIC GLIOMA Putri, Imey Pinasty Harianto; Indratama, I Nyoman Yudayana; Shiddiq, Muhammad Hilmy As; Josafat, Gantha Narendra; Priyanto, Bambang
Indonesian Journal of Health and Medical Education Vol. 1 No. 1 (2026): Edisi Januari-Juni 2026
Publisher : Indonesian Publication Center

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Abstract

Gliomas are the most common type of central nervous system neoplasms in children, exhibiting distinct clinical and biological characteristics compared to adult gliomas. Pediatric gliomas encompass various histological and molecular subtypes, ranging from low-grade gliomas (LGG) to high-grade gliomas (HGG) and diffuse intrinsic pontine glioma (DIPG), each with differing clinical presentations, treatment responses, and prognoses. This literature review discusses the definition, etiology, epidemiology, pathophysiology, clinical manifestations, diagnostic approaches, treatment modalities, and prognostic factors of pediatric gliomas. Advances in imaging and molecular technologies have enabled more precise diagnostic and therapeutic strategies. Treatment options include surgery, chemotherapy, radiotherapy, and targeted molecular therapies, tailored according to tumor grade and location. A comprehensive understanding of the biological and clinical aspects of pediatric gliomas is essential for improving patient prognosis and quality of life.
PATHOPHYSIOLOGY OF SKIN AGING: ROLE OF OXIDATIVE STRESS, INFLAMMATION, AND DERMAL REMODELING Sari, Baiq Merna Merta; Putri, Imey Pinasty Harianto; Muliana, Atriska Citra; Shafitri, Shira Shalsabina; Ilmiah, Janiya Abdila; Athalia, Ihza Namira; Aulia, Rashieka Salma; Josafat, Gantha Narendra; Shiddiq, Muhammad Hilmy As; Indratama, I Nyoman Yudayana; Prasetya, Rangga Cahya; Nurhidayati, Nurhidayati
Indonesian Journal of Health and Medical Education Vol. 1 No. 1 (2026): Edisi Januari-Juni 2026
Publisher : Indonesian Publication Center

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Abstract

The skin, as the largest organ of the human body, plays a vital role in protecting the internal systems from external environments. As age increases, the skin undergoes two types of aging: intrinsic, caused by genetic and hormonal factors, and extrinsic, due to environmental factors such as ultraviolet (UV) radiation and pollution. The aging process is characterized by a decrease in fibroblasts, which are responsible for producing collagen and elastin, leading to a reduction in skin strength and elasticity. Oxidative stress resulting from the accumulation of reactive oxygen species (ROS) contributes to DNA damage and triggers inflammatory responses that accelerate aging, manifesting as wrinkles and sagging skin. Chronic inflammation, induced by ROS, further supports premature aging by increasing inflammatory substances that cause redness and irritation of the skin. Additionally, dermal remodeling is a physiological process essential for maintaining healthy skin. Still, it can become pathological if there is an imbalance between synthesis and degradation of the extracellular matrix, thereby hastening signs of aging such as wrinkles and sagging skin. In efforts to combat skin aging, several pharmacological aspects, such as topical therapies using sunscreens, retinoids, and alpha hydroxy acids (AHAs), have proven effective. Furthermore, systemic antioxidant supplementation also contributes to skin condition improvement. This comprehensive review provides valuable insights into the mechanisms of skin aging, the importance of skincare, and therapeutic strategies to counteract premature aging.
GUNSTOCK DEFORMITY OF THE ELBOW: CLINICAL FEATURES, BIOMECHANICS, AND CURRENT TREATMENT STRATEGIES: A LITERATURE REVIEW Athalia, Ihza Namira; Putri, Imey Pinasty Harianto; Muliana, Atriska Citra; Shafitri, Shira Shalsabina; Ilmiah, Janiya Abdila; Sari, Baiq Merna Merta; Aulia, Rashieka Salma; Josafat, Gantha Narendra; Shiddiq, Muhammad Hilmy As; Indratama, I Nyoman Yudayana; Prasetya, Rangga Cahya; Nurhidayati, Nurhidayati
Indonesian Journal of Health and Medical Education Vol. 1 No. 1 (2026): Edisi Januari-Juni 2026
Publisher : Indonesian Publication Center

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Abstract

Gunstock deformity, also known as cubitus varus, is a common complication that arises after supracondylar humerus fractures in children, primarily due to malunion of the bone. This condition results in an inward deviation of the forearm when the elbow is in full extension, creating a pronounced change in contour that can significantly impact biomechanical function and the quality of life of the patient. Common clinical symptoms include pain on the lateral side of the elbow, limited range of motion, and joint instability, particularly associated with ulnar neuropathy. Diagnosis is established through physical examination and radiological imaging to identify the angle of deviation and malalignment. Management of this deformity varies based on severity, ranging from observation in mild cases to surgical interventions like osteotomy in more severe cases. Common corrective techniques include lateral closing wedge osteotomy and dome osteotomy, aimed at restoring anatomical alignment and preventing long-term complications. Postoperative rehabilitation is crucial for regaining joint function and muscle strength. Long-term prognosis is generally good; however, it requires appropriate management to avoid complications like joint stiffness and ulnar neuropathy. A comprehensive approach encompassing diagnosis, deformity correction, and rehabilitation is essential for achieving optimal functional outcomes.
Factors Affecting Adherence to Iron-Folic Acid Supplementation Among Adolescent Girls: An Integrative Review Shiddiq, Muhammad Hilmy As; Lestarini, Ima Arum; Restuningdyah, Novia Andansari Putri
Indonesian Journal of Applied Science and Technology Vol. 6 No. 1 (2025): Edisi Januari-Juni 2025
Publisher : Indonesian

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Abstract

Adherence to Iron-Folic Acid (IFA) supplementation is a critical strategy in preventing and overcoming anemia among adolescent girls. However, compliance rates remain inconsistent across various regions. This integrative review aims to identify and synthesize the multi-dimensional factors influencing adherence to IFA supplementation among adolescent girls. A total of 28 relevant studies, including quantitative, qualitative, and systematic reviews, were analyzed. The findings indicate that adherence is determined by several key factors: (1) Individual factors, including knowledge of anemia, attitudes towards supplements, and personal motivation; (2) Social and environmental support, particularly the crucial roles of family (parents) and school environments (teacher supervision); and (3) Programmatic interventions, such as culture-based nutrition education and the use of digital health applications. Barriers such as fear of side effects and lack of consistent information were also identified. This review concludes that a multi-sectoral approach involving schools and families, supported by innovative educational media, is essential to improve compliance and ensure the success of anemia prevention programs.
Co-Authors Ajmala, Indana Eva Ansary, Muhammad Fathir Rahadian Athalia, Ihza Namira Aulia, Rashieka Salma Baik Nilawati Astini Bambang Priyanto, Bambang Fadhila, Luthfiya Nur Fathoroni, Fathoroni G. Gunawan Gunawan Gunawan Hamsu Kadriyan Ilmiah, Janiya Abdila Ima Arum Lestarini Imran Imran Indratama, I Nyoman Yudayana Josafat, Gantha Narendra Lovy Herayanti Mertasari, Baiq Merna Muhammad Rifki Muliana, Atriska Citra Mussyafa, Aulia Putri Ni Made Yeni Suranti Nurhidayati Nurhidayati Prasetya, Rangga Cahya Putri, Imey Pinasty Harianto Rahmatullah Rahmatullah Restuningdyah, Novia Andansari Putri Sari, Baiq Merna Merta Shafitri, Shira Shalsabina Tunairin, Siti Raodatul Jannah Yahya, Fahmi Zuhan, Arif