Article Per Year (5 Year)
p-Index From 2021 - 2026
0.61
P-Index
This Author published in this journals
All Journal Andalas obstetrics and gynecology journal
Saputra, Mondale
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Nursing Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Isolated Mayer–Rokitansky–Kuster–Hauser syndrome (MRKH): Case Report Putri, Eka; Saputra, Mondale
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 1 (2023)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.1.312-319.2023

Abstract

Background:Mayer–Rokitansky–Kuster–Hauser syndrome (MRKH) is a rare complex of congenitalmalformations characterized by aplasia of the uterus and upper (two-thirds) vagina in a woman with normalovaries and fallopian tubes, secondary sexual characteristics and a 46XX karyotype. The clinical symptoms ofMRKH syndrome are usually primary amenorrhea but with normal thelarche and adrenarche, as well as sexualintercourse disorders and infertility.Case report:In this case, a 22-year-old nulliparous woman with a female phenotype and normal secondary sexgrowth presented with primary amenorrhea and difficulty in sexual intercourse. On internal examination, thelength of the vagina was 4 cm and the cervix was not palpable. Transvaginal ultrasound examination did not showa picture of the uterus, but both ovaries were normal size and there were several follicles. Diagnostic laparoscopyshowed bilateral ovaries with intact tubes, but no uterus.Conclusion: Women with MRKH syndrome usually have normal ovarian function and usually present withprimary amenorrhea. Treatment of MRKH syndrome must include sexological care of the patient and hispartner.6The American College of Obstetricians and Gynecologists (ACOG) recommends dilation therapy as firstlinetreatment and vaginoplasty surgery should be performed for patients who have failed dilation therapy.
The Effect of Inositol On Malondialdehyde Serum Levels in Medical Students With PCOS Nofityari, Eldisha; Saputra, Mondale; Ali, Hirowati
Andalas Obstetrics And Gynecology Journal Vol. 10 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.10.1.117-123.2026

Abstract

Introduction: Polycystic ovary syndrome involves the endocrine system, metabolic system, as well as the reproductive system contributing to anovulatory infertility. Polycystic ovary syndrome affects 5-20% of reproductive age and 6-12% of adolescents. Oxidative stress is known to play an important role in the pathogenesis of PCOS resulting in excessive formation of ROS (malondialdehyde). ROS can be controlled by the antioxidant inositol and has minimal side effects.  To determine the effectivity of inositol antioxidant on malondialdehyde serum levels in female students Medical faculty, Andalas University with clinical PCOS. Methods: This study is a clinical trial research with a pure experimental study design (true experimental design). There were 23 samples for the experimental group and 23 samples for the control group selected by probability sampling. Normality test using Shapiro-Wilk test. Data analysis using Independent T test and Mann Whitney Test. Results: There was a significant decrease in malondialdehyde serum levels in PCOS students who consumed inositol therapy for 3 months. Conclusion: There is an effect of inositol antioxidant consumption on malondialdehyde serum levels in female students Medical faculty, Andalas University with clinical polycystic ovary syndrome.
The Relationship Between Short Chain Fatty Acids and Menarche in Elementary School Students in Padang City Zulfiqar MS; Haviz Yuad; Yetti, Husna; Defrin, Defrin; Ferry, Ferdinal; Saputra, Mondale
Andalas Obstetrics And Gynecology Journal Vol. 10 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.10.1.145-152.2026

Abstract

Introduction: Early menarche is associated with long-term health problems. Currently, adolescent girls are increasingly experience the change of menarche age. Short chain fatty acids (SCFA) are known to play a role in the early release of GnRH which induces an earlier onset of menarche. However, so far there have been no human studies assessing SCFA levels in individuals with early menarche. Method: This is a case-control study in elementary school students in Padang which conducted from July 2024 to November 2024. The sample was all elementary school students in Padang who met the inclusion and exclusion criteria. The data collected were demographic data and SCFA levels measured in faecal samples using the ELISA method. Bivariate analysis was performed using the unpaired T-test. Result: In this study, there were 25 students with early menarche and 25 normal students. Students with early menarche experienced the earliest age of menarche in 9 years old, 56% had excessive BMI, 20% had mother history of early menarche, 20% were born prematurely, 52% had  high-fat diet, 100% lived with their parents and had no history of pornography exposure. This study found the differences in fecal SCFA levels based on age of menarche with the mean SCFA levels found to be higher in the early menarche group compared to normal menarche (39.09 ±  6.64 vs 26.91±5.01 μmol/gram; p=0.000) Conclusion: This study found the differences in fecal SCFA levels based on age of menarche
Co-Authors Defrin, Defrin Eka Putri Ferry, Ferdinal Haviz Yuad Hirowati Ali, Hirowati Husna Yetti Nofityari, Eldisha Zulfiqar MS