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EDUKASI APOTEKER CILIK: MENGGALI PEMAHAMAN PROFESI APOTEKER DAN PENERAPAN KONSEP DAGUSIBU SEJAK USIA DINI DI SD AL-IRSYAD AL-ISLAMIYAH Lusiana, Rebhika; Artabah Muchlisin, Muhammad; Salsabiella, Elok; Ahmad, Nabila; Ayu Margaretha, Miranda; Chasanah, Fadhilatul; Mumtaz, Adibah; Ericasia, Ira; Ayuningtyas Afthon, Ifa; Amelia Clarinta, Neysa; Triakbar Alharits, Fikri; Wahyuni, Sri
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 8, No 4 (2025): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v8i4.1418-1424

Abstract

Pendidikan kesehatan pada usia dini sangat penting untuk mengembangkan perilaku yang tepat terkait pengelolaan obat. Program-program seperti Apoteker Cilik (Apocil) dan DAGUSIBU (Dapatkan, Gunakan, Simpan, Buang) bertujuan untuk mengenalkan anak-anak pada praktik-praktik yang benar dalam mendapatkan, menggunakan, menyimpan, dan membuang obat, serta meningkatkan kesadaran tentang peran apoteker dalam pelayanan kesehatan. Tujuan: Penelitian ini bertujuan untuk menilai dampak program edukasi Apocil dan DAGUSIBU dalam meningkatkan pengetahuan siswa kelas 3 SD Al-Irsyad Al-Islamiyah tentang profesi apoteker dan pengelolaan obat yang benar. Metode: Desain penelitian kuantitatif digunakan dengan pendekatan pre-test dan post-test. Penelitian ini dilakukan terhadap 71 siswa kelas 3 SD Al-Irsyad Al-Islamiyah. Data dikumpulkan dengan menggunakan kuesioner untuk mengukur pemahaman siswa mengenai profesi apoteker dan penerapan konsep DAGUSIBU. Data dianalisis menggunakan uji-t dependen untuk membandingkan pengetahuan sebelum dan sesudah intervensi edukasi. Hasil: Hasil penelitian menunjukkan adanya peningkatan yang signifikan pada pengetahuan siswa, dengan skor rata-rata pre-test 42,92 dan post-test 98,13, yang mencerminkan peningkatan sebesar 39,14%. Analisis uji-t berpasangan menunjukkan nilai p=0,000 (p0,05), yang menunjukkan perbedaan yang signifikan secara statistik antara skor pre-test dan post-test. Kesimpulan: Program Apocil dan DAGUSIBU secara signifikan meningkatkan hasil belajar siswa.
Fibrinolytic Protease Production: Impact of Initial pH and Temperature in Solid-State Fermentation by Rhizopus microsporus var. oligosporus FNCC 6010 Lusiana, Rebhika; Poernomo, Achmad Toto; Syahrani, Achmad
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 10 No. 3 (2023): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v10i32023.290-299

Abstract

Background: Fibrinolytic enzyme is one of the cardiovascular disease therapies. Rhizopus microsporus var. oligosporus is microorganism that has been evaluated to produce fibrinolytic protease by fermentation. This study conducted fermentation of helianthi annui semen (sunflower seed) by Rhizopus microsporus var. oligosporus to produce fibrinolytic enzyme. Objective: This study aims to determine the effect of Initial pH and incubation temperature and its optimization in the production of fibrinolytic protease by Rhizopus microsporus var. oligosporus FNCC 6010 in solid-state fermentation on helianthi annui semen (sunflower seed) substrate.  Optimum condition was determined by maximum protease and fibrinolytic activity. Method: A crude enzyme of protease fibrinolytic was obtained from the supernatant extract of fermented sunflower seed. Protease activity was measured by the skimmed milk agar (SMA) plate method, and fibrinolytic activity was determined by the fibrin agar plate method. Result: It was found that the starting pH affects both the proteolytic and fibrinolytic activity of enzymes that are produced in fermentation. The starting pH of 5.0 showed higher fibrinolytic and proteolytic activity values compared to the starting pH of 7.0. The incubation temperature 33±1 °C had the higher activity compared to 28±1 °C or 37±1 °C. Conclusion: Initial pH and incubation temperature affect the proteolytic and fibrinolytic activity of crude enzyme extracted from fermented sunflower seed by Rhizopus microsporus var. oligosporus. The optimum condition for producing fibrinolytic protease in the state fermentation method was an initial pH of 5.0 and an incubation temperature of 33±1°C.
Edukasi Interaksi Obat dan Makanan dalam Mendukung Penggunaan Obat yang Aman pada Siswa SMK Farmasi Maharani Malang Lusiana, Rebhika; Rahmi, Amalia; Insani, Nabilah; Habibi, Muhammad Rafli; Rizky, Ihza Fadillah; Syekhan, Muhammad Alief; Albaniray, Titania Tianka; Abida, Ismi; Nazzala, Salsabilla Aghnia; Nurunnailah, Aqila; Putri, Anjeli Oktaviana
Jurnal Pengabdian Nasional (JPN) Indonesia Vol. 7 No. 1 (2026): Januari
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LPPM) STMIK Indonesia Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63447/jpni.v7i1.1768

Abstract

This counseling activity aimed to increase awareness and understanding of students at SMK Farmasi Maharani Malang regarding drug–food interactions in supporting the safe and appropriate use of medicines. Limited knowledge about drug–food interactions among adolescents may lead to reduced therapeutic effectiveness, increased risk of side effects, and inappropriate medication use. Therefore, educational activities are necessary to provide accurate information about the influence of food on drug therapy. The implementation method consisted of several stages: (1) a pre-test to assess students’ initial knowledge regarding drug food interactions; (2) an educational session delivered through PowerPoint presentations accompanied by interactive discussions and an educational crossword puzzle activity using printed media; and (3) a post-test to evaluate the improvement in students’ understanding after the educational intervention. Both the pre-test and post-test were conducted independently using Google Forms. The activity was carried out on Monday, December 1, 2025, and involved Grade XII students of SMK Farmasi Maharani Malang. The evaluation results showed an improvement in students’ understanding after participating in the educational activity. A comparison between pre-test and post-test results indicated an increase in students’ knowledge regarding types of drug–food interactions and safe medication use. This improvement demonstrates that the educational approach applied was effective in enhancing students’ medication literacy. It is expected that students who have gained this knowledge will be able to apply it in their daily lives and act as agents of change in disseminating accurate information about safe medication use to their families and communities.