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All Journal JURNAL KIMIA SAINS DAN APLIKASI Jurnal Kimia Khatulistiwa Chemistry Indonesian Journal of Chemical Research Jurnal Mandala Pharmacon Indonesia Makara Journal of Science Sewagati: Jurnal Pengabdian Masyarakat Indonesia Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia Indonesian Journal of Educational Science and Technology (Nurture) Antigen: Jurnal Kesehatan Masyarakat dan Ilmu Gizi Harmoni Sosial : Jurnal Pengabdian Dan Solidaritas Masyarakat Jurnal Inovasi dan Terapan Pengabdian Masyarakat Fundamentum: Jurnal Pengabdian Multidisiplin Indonesian Journal of Herbal and Biomedical Research
Fath Dwisari
Politeknik 'Aisyiah Pontianak
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Edukasi Bahaya Formalin, Cara Identifikasi dan Upaya Penurunan Risiko pada Produk Pangan di MAN 3 Pontianak Dermawan, Abdurraafi' Maududi; Dwisari, Fath; Jumadilah, Rahmi; Tjoadri, Tessa Nathalia
FUNDAMENTUM : Jurnal Pengabdian Multidisiplin Vol. 2 No. 1 (2024): Februari : FUNDAMENTUM : Jurnal Pengabdian Multidisiplin
Publisher : Asosiasi Peneliti Dan Pengajar Ilmu Sosial Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/fundamentum.v2i3.342

Abstract

The use of formalin as a food additive is prohibited according to Indonesian Minister of Health Regulation No. 033 of 2012 concerning Food Additives (BTP). Due to its easy availability and its ability to extend shelf life, formalin is often misused as a food preservative. Given its carcinogenic properties, the use of formalin in food poses health risks. The purpose of this community service is to provide education on the dangers of formalin, identification techniques for formalin, and de-formalization efforts in food products. The community service was conducted on July 25, 2024, with 30 students from MAN 3 Pontianak participating. The service was carried out using an outreach method at MAN 3 Pontianak, including pre-tests, material delivery, demonstrations, and post-tests. The results from the pre-test and post-test show an average knowledge increase of 19% regarding formalin risks and reduction efforts. Following the education through material presentation and demonstrations, the number of students with good knowledge increased to 26 (86.7%), while those with insufficient knowledge decreased to 4 (13.3%). The attitude assessment revealed that all students at MAN 3 Pontianak had a positive attitude towards the dangers of formalin and efforts to reduce formalin risks in food (100%).
Evaluation of the Antimicrobial Efficacy of Hibiscus sabdariffa L. Antiperspirant Preparations Against Staphylococcus epidermidis Dwisari, Fath; Dermawan, Abdurraafi Maududi; Amalia, Puspa; Tjoadri, Tessa Nathalia; Rahma, Nur Atika
Indonesian Journal of Chemical Research Vol 13 No 2 (2025): Edition for September 2025
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2025.13-fat

Abstract

Commercial antiperspirant products commonly incorporate synthetic compounds, several of which have raised concerns due to their potential carcinogenicity. Moreover, the inclusion of natural antibacterial agents in these formulations remains limited. Hibiscus sabdariffa L. (Rosella), a plant rich in bioactive secondary metabolites, offers a promising natural alternative. This study aimed to evaluate the antibacterial efficacy of rosella-based antiperspirant formulations, particularly against Staphylococcus epidermidis, a key contributor to body odor. Three formulations (F1, F2, and F3) were developed and assessed based on several parameters: pH, organoleptic properties, homogeneity, spreadability, adhesiveness, and antibacterial activity against Staphylococcus epidermidis. The results demonstrated that the antiperspirant preparations complied with standard evaluation criteria. Furthermore, the antibacterial assay outcomes yielded statistically significant differences (p < 0.05) in the mean diameter of the inhibition zones, indicating that H. sabdariffa L. exhibited measurable antibacterial activity against S. epidermidis. These findings support the potential application of Rosella extract in developing natural and efficacious anti-perspirant products.
Determination of Vitamin C Levels in Various Chilli (Capsicum sp) Varieties and In-Silico Activity Assessment Dwisari, Fath; Dermawan, Abdurraafi' Maududi
Jurnal Mandala Pharmacon Indonesia Vol. 10 No. 2 (2024): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v10i2.523

Abstract

Chili peppers are acknowledged as one of the fruits endowed with a notable vitamin C content, a crucial nutrient integral to various physiological processes. These include collagen synthesis, bone and tooth formation, wound healing, and bolstering the immune system's defense against infections. Vitamin C, as a water-soluble compound, is susceptible to degradation when exposed to atmospheric conditions. Hence, careful preservation of chili peppers is imperative to maintain their vitamin C levels. The primary objective of this study is to discern the concentrations of vitamin C within three distinct stages of chili pepper ripeness: young, semi-ripe, and fully ripe. The methodology employed in this investigation entails UV-Vis Spectrophotometry, with a maximal wavelength for vitamin C quantification established at 265 nm. This approach yielded absorbance values of 0.696, 0.564, and 0.478 for the respective stages. Quantitative analysis reveals that the vitamin C concentrations in young, semi-ripe, and fully ripe chili peppers are 8.1397 ppm, 5.9559 ppm, and 4.5313 ppm, respectively. These findings unequivocally demonstrate that vitamin C content is significantly higher in young chili peppers when compared to their semi-ripe and fully ripe counterparts. The docking results for capsaicin ligands yielded Gibbs energy (?G), Ki and IC50 value -6.14 kkal/mol, 31.34 µm and 19.143 ppm, respectively. The result indicate that capsaicin exhibited good interaction to catalytic site of glycogen phosphorylase which could serve as a potential antidiabetic agent.
Antibacterial Activity of Bajakah Tampala (Spatholobus littoralis Hassk.) Methanol Extract in Roll-On Deodorant against Staphylococcus epidermidis Dwisari, Fath; Dermawan, Abdurraafi' Maududi; Rahma, Nur Atika; Tjoadri, Tessa Nathalia; Abidin, Khoirul Rista
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.865

Abstract

Body malodor results from the bacterial breakdown of apocrine gland secretions, with Staphylococcus epidermidis identified as a key contributor. Conventional deodorants often rely on synthetic compounds that may cause skin irritation or pose long-term health risks. This study aimed to formulate and assess an antibacterial roll-on deodorant containing methanolic extract of Spatholobus littoralis Hassk., a Kalimantan-native medicinal plant known for its antibacterial properties. The extract, prepared via maceration, was incorporated into a multiphase emulsion base comprising zinc ricinoleate, aluminum potassium sulfate, Carbopol 940, triethanolamine, Lexemul CS20, BHT, and phenoxyethanol. The formulations were evaluated for their physicochemical characteristics—pH, spreadability, adhesiveness, and homogeneity—as well as antibacterial activity against S. epidermidis using the disc diffusion assay. The extract-containing formulations (F1–F3) exhibited a beige color, herbal aroma, and uniform texture. The pH values (4.12–4.35) were within the dermally acceptable range. The spreadability varied from 4.59 to 4.81?cm, while the adhesiveness ranged from 0.34?s to 5.25?min, indicating favorable application and retention properties. Antibacterial testing showed inhibition zones of 10.40–12.37?mm, comparable to a commercial control (p?>?0.05). These findings suggest that S. littoralis extract is a potential natural, skin-compatible antibacterial agent for topical deodorant applications
Efek Perendaman Ikan Asin Sepat dalam Cuka Makan terhadap Penurunan Kadar Formalin Abdurraafi’ Maududi Dermawan; Dwi Haryadi; Fath Dwisari
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 2 No. 1 (2024): Februari : Antigen: Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v2i1.189

Abstract

There are still many salted fish producers or sellers who misuse formalin to preserve salted fish. Because of its easy availability and can extend shelf life, this chemical is often misused as a food preservative, and its carcinogenic nature the use of formalin in food can have a negative impact on health. Various efforts and previous studies have been carried out to deformalize and reduce formalin levels in food, one of which is through the use of table vinegar in reducing the formalin content of Salted Sepat Fish. The study aims to determine the effect of soaking in vinegar solution to reduce the formalin content in Salted Sepat Fish and determine the concentration of vinegar solution that is effective in reducing formalin levels in Salted Sepat Fish. The study was conducted as a true experimental research with Pre and Post Test Control Group research design. Samples of Salted Sepat Fish used in this study were obtained from several traditional markets in Pontianak City (Flamboyan Market, Tengah Market, Dahlia Market, Teratai Market and Kemuning Market). The results showed that there was a decrease the concentration of formalin after soaking with 25% dining vinegar solution at 6%, 8% and 10% concentration variations with a percentage decrease of 23.32%; 50.77% and 68.21% respectively. The solution of table vinegar with a concentration of 8% was the most effective in reducing formalin levels in Salted Sepat Fish.
Evaluasi Efektivitas Daun Bayam Merah (Amaranthus tricolor L.) Berdasarkan Waktu Perendaman sebagai Pewarna Alternatif pada Pemeriksaan Escherichia coli Kalisti Meriani Papalanggi; Fath Dwisari; Puspa Amalia
Indonesian Journal of Herbal and Biomedical Research Vol. 1 No. 1 (2025)
Publisher : Bahiraliya Natura Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66982/ijhbr.v1i1.4

Abstract

Escherichia coli is one of the Gram negative bacteria and the main bacteria that causes diarrhea. The identification of E. coli can be used by Gram staining using safranin. However, safranin has several limitations, which are expensive and carcinogenic. Therefore, an alternative dyes based on natural compounds such as red spinach leaves are needed. The purpose of this study was to determine the potential of soaking time variations of red spinach leaves (Amaranthus tricolor L) as an alternative dye and the effect of soaking time variations on the examination of Escherichia coli staining. This research was conducted by quasi-experiments, using purposive sampling with a total of 27 samples and safranin as positif control. The Fisher's exact statistical test obtained p-value<0.05 which stated there were difference between red spinach leaves and safranin in staining of E. coli bacteria. The present study exhibited the potency of (Amaranthus tricolor L.) as an alternative dye for E. coli staining, but had not shown better results compared to safranin.
Analisis Pengaruh Waktu Fermentasi terhadap Konsentrasi Etanol pada Kulit Pisang Raja (Musa acuminata) dan Pisang Kepok (Musa paradisiaca L) Rahmadian Hoirunnisa; Khoirul Rista Abidin; Fath Dwisari; Abdurraafi' Maududi Dermawan
Indonesian Journal of Herbal and Biomedical Research Vol. 1 No. 1 (2025)
Publisher : Bahiraliya Natura Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66982/ijhbr.v1i1.5

Abstract

Banana peel waste is frequently discarded without proper management, potentially causing long-term environmental problems. However, banana peels can be valorized as a renewable feedstock for ethanol production. This study employed a quantitative experimental design consisting of four main stages: sample preparation, sulfuric acid hydrolysis, yeast fermentation with fermentation time variations of 72, 120, and 168 h, and ethanol content analysis. The ethanol content obtained from Raja banana (Musa acuminata) peels at fermentation times of 72, 120, and 168 h was 15%, 16%, and 17%, respectively. Meanwhile, ethanol yields from Kepok banana (Musa paradisiaca L.) peels at the same fermentation durations were 17.66%, 20.33%, and 22.33%, respectively. The results indicated that the highest ethanol content for both Raja and Kepok banana peels was achieved at a fermentation time of 168 h. Friedman test analysis revealed significance values of 0.368 (> 0.05) for Raja banana peels and 0.097 (> 0.05) for Kepok banana peels, indicating no statistically significant differences in ethanol content among the three fermentation durations. Overall, an increasing trend in ethanol content was observed for both banana varieties with prolonged fermentation time; however, statistical analysis confirmed that the differences were not significant across the tested fermentation periods.
Uji Aktivitas Anti Jerawat Krim Kratom (Mitragyna speciosa) pada Tikus Wistar yang Diinduksi Propionibacterium acnes Ariffialdi Nurhidyattulloh; Fath Dwisari; Adelia Chintya Ningrum; Khoirul Rista Abidin; Abdurraafi’ Maududi Dermawan; Nur Arsella; M. Dzaki Al Ghifari; M. Fikri Amrulloh; M. Erik Fernando; Sulisti Okta Romadhon
Jurnal Mandala Pharmacon Indonesia Vol. 12 No. 1 (2026): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v12i1.1104

Abstract

Jerawat (acne vulgaris) merupakan gangguan kulit inflamasi kronis yang berhubungan dengan inflamasi akibat Propionibacterium acnes (P. acnes). Meningkatnya kekhawatiran terhadap resistensi antibiotik mendorong pencarian alternatif terapi topikal berbasis bahan alam. Mitragyna speciosa (M. speciosa), yang dikenal sebagai kratom, mengandung metabolit sekunder bioaktif seperti alkaloid, flavonoid, senyawa fenolik, dan saponin yang dilaporkan memiliki aktivitas antibakteri dan antiinflamasi. Penelitian ini bertujuan mengevaluasi potensi anti jerawat dari krim topikal yang diformulasikan menggunakan ekstrak metanol M. speciosa. Sampel diekstraksi dengan metode maserasi, dilanjutkan dengan skrining fitokimia dan formulasi krim dengan konsentrasi ekstrak 5%, 10%, dan 15%. Aktivitas antibakteri terhadap P. acnes diuji menggunakan metode difusi cakram. Uji in vivo dilakukan pada tikus Wistar betina yang diinduksi P. acnes, dibagi ke dalam lima kelompok (n = 6 per kelompok), yaitu kontrol tanpa terapi (Acnes), asam azelaic (Aaz), serta tiga kelompok perlakuan krim ekstrak (MG 5, MG 10, MG 15). Tingkat keparahan jerawat dinilai melalui skor klinis dan pemeriksaan histopatologi jaringan telinga. Skrining fitokimia mengonfirmasi keberadaan alkaloid, flavonoid, fenol, dan saponin. Krim ekstrak konsentrasi 10% dan 15% menghasilkan zona hambat masing-masing sebesar 7,97 ± 0,40 mm dan 8,27 ± 0,91 mm, lebih rendah dibandingkan krim asam azelaic 20% (15,80 ± 0,00 mm). Analisis nonparametrik menggunakan uji Kruskal–Wallis menunjukkan tidak terdapat perbedaan yang signifikan antar kelompok pada hari ke-3 dan ke-5 (p > 0,05). Meskipun demikian, kelompok perlakuan ekstrak menunjukkan kecenderungan penurunan skor jerawat secara deskriptif, yang didukung oleh perbaikan gambaran histopatologis jaringan telinga. Temuan ini mengindikasikan adanya potensi aktivitas biologis krim ekstrak metanol M. speciosa sebagai kandidat terapi topikal jerawat, namun efektivitasnya masih memerlukan konfirmasi melalui optimasi formulasi dan penelitian lanjutan dengan kekuatan statistik yang lebih memadai.
Co-Authors Abdurraafi' Maududi Dermawan Abdurraafi’ Maududi Dermawan Abidin, Khoirul Rista Ade Cintyia Sally Adelia Chintya Ningrum Afriani, Natia Ainun Sa'adah Alma Miranda Amalia, Puspa Ariffialdi Nurhidyattulloh Azmi, Khulul Dermawan, Abdurraafi Maududi Dwi Haryadi Fitri Khotimatus Sa'adah Jumadilah, Rahmi Kalisti Meriani Papalanggi Khoirul Rista Abidin Khoirul Rista Abidin M. Dzaki Al Ghifari M. Erik Fernando M. Fikri Amrulloh Mohammad Farid Rahman Mohammad Farid Rahman Nur Arsella Nurli Arnida Nurza Wahyuningsih Pangesti, Laras Purwanti, Desi Asih Puspa Amalia Rahma, Nur Atika Rahmadian Hoirunnisa Ramadhani, Natasya Intan Samsiah Samsiah Siti Mariyah Ulfa Sulisti Okta Romadhon Tilawaty Aprina Tjoadri, Tessa Nathalia Tri Utari