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All Journal Buletin Veteriner Udayana
I Wayan Nico Fajar Gunawan
Laboratorium Ilmu Bedah dan Radiologi Veteriner, Fakultas Kedokteran Hewan Universitas Udayana, Jl. PB. Sudirman, Denpasar, Bali, Indonesia, 80234
Immunology & microbiology Public Health Veterinary

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MACROSCOPIC EVALUATION OF INCISION WOUND HEALING IN THE SKIN OF WHITE RATS TREATED WITH PLATELET-RICH PLASMA GEL DERIVED FROM PIG BLOOD Made Amara Sanjiwaning Sukma; I Wayan Wirata; I Wayan Nico Fajar Gunawan; I Gusti Ngurah Sudisma; I Made Kardena
Buletin Veteriner Udayana Bul. Vet. Udayana. February 2025 Vol. 17 No. 1
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i01.p22

Abstract

Wound healing is the body's attempt to restore its structural integrity and normal function after tissue disruption. Platelet Rich Plasma (PRP) is often used as a regenerative treatment by increasing the activity of growth factors in the blood to treat damaged tissue. Pig blood contains a high concentration of platelets that can support the wound healing process. The purpose of this study was to determine the macroscopic picture of incision wound healing on the skin of white rats given PRP gel from pig blood. The experimental animals used in this study were 27 wistar strain rats. There were three treatments carried out, namely the negative treatment group given 0.9% NaCl solution, the positive control group given bioplacenton, and the treatment group with pig blood PRP gel. Parameters used to determine the level of wound healing include wound length, wound color, wound moisture, and wound scab. Wound length data was analyzed using one-way analysis of variance (Anova). Meanwhile, data on wound color, wound scab, and wound moisture were analyzed by Kruskal Walls. The pig blood PRP gel treatment group had a significant effect on the incision wound healing rate than the negative and positive treatment groups (bioplacenton). PRP gel from pig blood can accelerate wound healing because it contains many growth factors that play an important role in tissue repair and regeneration. Further research is recommended to evaluate the effect of PRP on other types of wounds, such as burns or infectious wounds, as well as developing PRP preservation methods in other forms for wider clinical applications.
CYSTOLITHIASIS WITH ASSOCIATED HYDRONEFROSIS IN A FEMALE PERSIAN CAT: A CASE REPORT Valerie Xylia Tay; I Nyoman Suartha; Sri Kayati Widyastuti; I Wayan Nico Fajar Gunawan
Buletin Veteriner Udayana Bul. Vet. Udayana. October 2025 Vol. 17 No. 5
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i05.p03

Abstract

This report describes the diagnosis and management of cystolithiasis in an 8-year-old, spayed female Persian cat weighing 2.85 kg. The patient presented with a history of dysuria and hematuria that began nine months post-ovariohysterectomy. The symptoms initially resolved but recurred with greater severity a few days prior to presentation. Diagnostic tests, including urinalysis and ultrasonography, revealed hyperechoic particles within the urinary bladder and calcium oxalate crystalluria. A diagnosis of calcium oxalate cystolithiasis was made. The owner opted for conservative management, which included a prescription urinary diet and a daily herbal supplement (Keji Beling®). Clinical signs, including dysuria, resolved within seven days of treatment. However, calcium oxalate crystalluria persisted on follow-up urinalysis. This case suggests that conservative management can resolve the clinical signs of cystolithiasis, but long-term dietary control remains essential to manage the underlying risk of crystal formation. The role of herbal therapy in managing this condition requires further investigation.
Co-Authors I Gusti Ngurah Sudisma I Made Kardena I Nyoman Suartha I Wayan Wirata Made Amara Sanjiwaning Sukma Sri Kayati Widyastuti Valerie Xylia Tay