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Urfa, Aghna
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Humanities Decision Sciences, Operations Research & Management Languange, Linguistic, Communication & Media Medicine & Pharmacology Social Sciences Other

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Tinjauan : Antielastase dari Berbagai Tumbuhan untuk Kosmetik Handayani, Retty; Arlina, Delin; Ekaputri, Syifa Nurisma; Nurajijah, Siti; Sopiana, Siti Nurmulyanti; Fadilla, Farisha Rahma; Urfa, Aghna
Journal of Pharmascience Vol 12, No 2 (2025): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i2.21963

Abstract

Antielastase adalah senyawa yang menghambat aktivitas enzim elastase, yang berperan dalam mencegah kerusakan jaringan elastin di dalam tubuh. Tujuan review jurnal ini yaitu merangkum berbagai jenis senyawa bioaktif dari tumbuhan yang berkhasiat sebagai antielastase. Metode review yang digunakan mencakup berbagai pendekatan literatur yang dilakukan melalui tahapan pencarian artikel, seleksi, penentuan artikel, dan ekstraksi data. Proses pencarian artikel dilakukan pada database bereputasi seperti Google Scholar, OpenAlex, Pubmed, Sciendirect, Sinta, dan Scopus. Hasil dari 50 literatur menunjukkan bahwa semua tanaman yang diteliti mempunyai senyawa yang berpengaruh besar sebagai inhibitor enzim elastase alami dengan nilai IC50 kurang dari 50ppm. Senyawa dari tanaman tersebut yaitu golongan polifenol, flavonoid, α-tocopherol, biflavonoid, fenol, epigallocatechin gallate (EGCG), epicatechin gallate (ECG), antosianin, katekin, α-pinene, limonene, likopen, quercetin, dan safranal. Penelitian ini menunjukkan bahwa terdapat banyak literatur yang mendukung pemanfaatan tanaman sebagai agen antielastase. Kata Kunci: Anti-Aging, Fitokimia, IC50, Inhibitor Elastase, Senyawa Bioaktif Antielastase is a compound that inhibits the activity of the elastase enzyme, which plays a role in preventing damage to elastin tissue in the body. The purpose of this journal review is to summarize various types of bioactive compounds from plants that are efficacious as antielastase. The review method used includes various literature approaches carried out through the stages of article search, selection, article determination, and data extraction. The article search process was carried out on reputable databases such as Google Scholar, OpenAlex, Pubmed, Sciendirect, Sinta, and Scopus. The results of 50 literatures showed that all plants studied had compounds that had a major effect as natural elastase enzyme inhibitors with IC50 values of less than 50 ppm. The compounds from these plants are polyphenols, flavonoids, α-tocopherol, biflavonoids, phenols, Epigallocatechin Gallate (EGCG), Epicatechin Gallate (ECG), anthocyanins, catechins, α-pinene, limonene, lycopene, quercetin, and safranal. This study shows that there is a lot of literature supporting the use of plants as antielastase agents.
The The Stunting Prevention Counseling Through Early Detection and Management of Pregnancy Disorders in Sukahaji Village, Sukawening, Garut Qowiyyah, Atun; Hilman, Irfan; Luthfiyyah, Hasnaa; Urfa, Aghna; Permana, Elpan Gustian; Sarah, Siti; Rizalianti, Nayla Rahmiyya; Humaira, Yasmina Rihada; Afifah, Risa Asvia; Fauziyah, Fahmi; Kartika, Sumi Sulfia; Nuraini, Annisa; Rahman, Wildan; Syahla, Nazwa Alifah; Sofyan, Ananda; Fazri, Shintya Nur; Adiningsih, Sri Astuti; Paridwan, Angga; Januar, Ariel Hasnan; Saefulloh, Ade; Abdulloh, Syehhabudin; Nugraha, Elfa Widiyanto
Indonesian Journal of Community Empowerment (IJCE) Vol 7 No 1 (2026): Indonesian Journal of Community Empowerment (Februari)
Publisher : Fakultas Kewirausahaan Universitas Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35899/ijce.v7i1.1136

Abstract

Stunting remains a major public health issue in Indonesia. In Sukahaji Village, 56 stunted children, 8 infant deaths, and 48 pregnant women at risk were recorded due to inadequate nutrition and maternal health monitoring. This activity aimed to improve the knowledge of pregnant women, prospective mothers, and health cadres regarding nutrition, pregnancy care, and early stunting prevention. Health education was conducted using a participatory approach through lectures, discussions, Q&A sessions, and educational media. Evaluation was carried out using pretest and postest instruments. Participants’ knowledge significantly improved; the “good” category increased frpm 31% to 69%, while the “poor” category decreased from 25% to 6%. Participatory health education effectively improved knowledge and has strategic implications for preventing stunting and reducing infant mortality in Sukahaji Village.
Co-Authors Abdulloh, Syehhabudin Adiningsih, Sri Astuti Afifah, Risa Asvia Arlina, Delin Atun Qowiyyah Ekaputri, Syifa Nurisma Fadilla, Farisha Rahma Fauziyah, Fahmi Fazri, Shintya Nur Handayani, Retty Humaira, Yasmina Rihada Irfan Hilman, Irfan Januar, Ariel Hasnan Kartika, Sumi Sulfia Luthfiyyah, Hasnaa Nugraha, Elfa Widiyanto Nuraini, Annisa Nurajijah, Siti Paridwan, Angga Permana, Elpan Gustian Rizalianti, Nayla Rahmiyya Saefulloh, Ade Siti Sarah, Siti Sofyan, Ananda Sopiana, Siti Nurmulyanti Syahla, Nazwa Alifah Wildan Rahman