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Effects of Ethanolic Extracts of Fruits of Acacia nilotica and Flowers of Calotropis procera on Liver Function of Aspirin-Induced Male Albino Rats Muhammad Zuhairah Ismail; Imo Chinedu; Arowora Kayode Adebisi; Shadrach Philip; Rashida Ismail Mohammed; Isaac John Umaru; Kingsley Iyoko Iseko; Dafup Katdel Istifanus
African Journal of Biochemistry and Molecular Biology Research Vol 1 No 1 (2024): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v1i1.3675

Abstract

This study examined the effects of ethanolic extracts of fruits of Acacia nilotica and flowers of Calotropis procera on the liver function of male albino rats. Acacia nilotica fruits and Calotropis procera flowers are commonly consumed by natives in northern Nigeria for therapeutic purposes. Eighty-four (84) healthy male albino rats were used for this study. The animals were randomly distributed into six groups of ten animals each, while 24 rats were used for lethal dose (LD50) analysis. The animals were administered ethanolic extracts of fruits of Acacia nilotica and flowers of Calotropis procera for 5 and 14 days respectively after induction with aspirin. The study was carried out in two phases: The animals were induced with 500 mg/kg body weight of aspirin 12 hours before the commencement of the experiment, the test animals were administered ethanolic extract of fruit of Acacia nilotica and flowers of Calotropis procera for 5 and 14 days and sacrificed at the end of each test phase respectively, blood was collected for biochemical analysis. The liver was harvested at the end of each phase, processed for histological investigation and photomicrographs taken. The result of liver function parameters showed that the mean values of alanine transaminase (ALT) after five-day of treatment decreased non-significantly (p>0.05) in groups 4, 5 and 6 and decreased significantly (p<0.05) in group 4 when compared to normal control. Also, ALT increased significantly (p<0.05) in group 2. There was a general decreasing trend in the mean values of aspartate transaminase (AST) across all groups except group 2. The mean values of alkaline phosphatase (ALP) decreased significantly (p<0.05) in all groups, but increased non-significantly in group 2. The same trend was observed in the values of ALT, AST, and ALP after 14 days of treatment. Photomicrograph of the liver section of normal rats showed normal central vein, sinusoids and hepatocytes as well as that of the treated animals. Photomicrograph of liver section of rat administered aspirin only showed slightly dilated portal triad after five days. The study suggests that the ethanolic extracts from fruits of Acacia nilotica and flowers of Calotropis procera may have active ingredients that are capable of improving some liver functions.
Effect of Heavy Metals and Risk Analysis on Arable Farmlands in Selected Local Government Areas of Southern Taraba State, Nigeria Bilyaminu Habibu; Otitoju Olawale; Yakubu Ojochenemi Ejeh; Isaac John Umaru; John Odiba Oko; Chukuma Stephen Ezeonu; Egbeadumah Maryanne Odufa
African Journal of Biochemistry and Molecular Biology Research Vol 1 No 2 (2024): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v1i2.3819

Abstract

Heavy metals are naturally occurring metallic elements that have a relatively high density compared to water. In most of the continent including Africa, the lack of food quality usually stand to be one of the major problem in which most of the food items are laden with lots of pollutants from heavy metals. Soil is said to be the reservoir of nutrients as well as pollutants. These pollutants have been implicated in causing lots of Health issues on human and Animals. Agricultural soil plays major role in food safety, food scarcity and food security, consumption of contaminated foods has serious implication on Human and Animals health. Heavy metals are potential environmental pollutants which are toxic to the human health. When present in an Arable land, they have the ability to bio-accumulate in the soil then to crops and eventually get to humans through food consumption. This study is able to evaluate the effect of heavy metals and risk analysis of arable farmlands in some selected local government areas of southern Taraba state (Donga, Wukari and Takum). All samples were processed, and heavy metals (Pb, Cd, Cr, Hg, and As) concentration were assayed using Atomic Absorption Spectrophotometry (AAS). The results showed that Chromium had a high concentration across all the studied areas with values ranging from 1.40 mg/kg to 2.25 mg/kg. However, Cadmium followed with values ranging from 0.04 mg/kg to 0.07 mg/kg and Arsenic with values ranging from 0.03 mg/kg to 0.06 mg/kg while Lead and Mercury had the lowest concentration of less than 0.03 mg/kg across the three LGAs. Ecological Risk Assessments parameters; Target Cancer Risk, Hazard Index (HI) and Estimated Daily Intake (EDI) were determined to assess the non-carcinogenic health risk. Takum recorded the highest levels of HM having the highest health risk followed by Wukari, whereas Donga had the lowest. Consistent use of crops harvested from the sampled location may pose a serious health challenge; bio-accumulation of toxicants in the soil across the studied areas may pose a health risk due to high concentration of heavy metals which are known to generate free radicals that may lead to oxidative stress and other cellular damages in humans.
Effect of Administration of Copper plasma Activated water and Anesthetic on Hematological and Pancreatic tissues of Wister rats Isaac John Umaru; Iseko Iyoko Kingsly; Prince Kwadwo Gyasi; Edom Favour Ogochukwu; Tensaba Andes Akafa; Jackson Soyinka Malantso; Bilyaminu Habibu; Kerenhappuch Isaac Umaru
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 1 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i1.4722

Abstract

In biomedicine, applications of PAW span from biofilm removal, wound healing, deactivation of bacteria and viruses, dentistry (for teeth disinfection and whitening), and cancer therapy. The biochemical activity of PAW is derived from synergistic effects of the highly reactive species, specifically reactive oxygen and nitrogen species (RONS). PAW is considered a biofriendly and prospective solution for biotechnology applications due to the time dependent nature of its biochemical activity because of the active species, and its economic and environmental benefits of using air rather than toxic chemicals as the raw material. Thus, the study on Effect of Administration of Copper plasma Activated water and Anaesthetic on Haematological and Pancreatic tissues of Wister rats. Material and Methods: Preparation of plasma-activated water a non-thermal micro-hollow cathode discharge (MHCD) was used to generate plasma-activated waters (CU-PAWs). Results: The results showed the haematological profile of the animals treated with 400mgkg-' had a decrease in Haemoglobin, Mean capsular Haemoglobin (11.21 ± 1.23 and 22.93 ± 21.11) compared to the controlled group (15.03 ± 1.72 and 29.93 ± 7.27) and in animals treated with 200mgkg-1 and 400mgkg-1 there is a significant decrease in the platelets (21.96 ± 23.16 and 20.89 ± 24.03) compared to animals on control group (32.08± 16.70) (table 2). Animals treated with 200mgkg-' and 400mgkg-' have a decrease in platelet (22.36 ± 4.88 and 20.89 ± 24.03) compared to animals on control (32.08 ± 16.70) and also animals treated with 400mgkg-1 have an elevated white blood cell count 173-56 ± 4.50) compared to the control group (3.66 ± 3.06). Conclusion: Cupper plasma water is safe to be used since it do not have much effect on the blood biochemistry and haematological parameters unlike the aesthetic agents cause changes on the haematological and blood biochemistry parameters. Hence, it is important to be aware of the effects of these agents before using them in experiments.
Snake Venom: Its Biochemical Components and Their Uses in Medicine Isaac John Umaru; Wisdom L. Benjamin
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 1 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i1.4931

Abstract

Snake venoms have components with diverse biological actions that are extensively studied to identify elements that may be useful in biomedical sciences. In the field of autoimmunity and rheumatology, various findings useful for the study of diseases and potential drug development have been reported. The study of disintegrins, proteins that block the action of integrins, has been useful for the development of antiplatelet agents and principles for the development of immunosuppressants and antineoplastic. Several proteins in snake venoms act on the coagulation cascade, activating factors that have allowed the development of tests for the study of coagulation, including Russell’s viper venom time, which is useful in the diagnosis of antiphospholipid syndrome. Neurotoxins with either pre- or postsynaptic effects have been used to study neurogenic synapses and neuromuscular plaques and the development of analgesics, muscle relaxants and drugs for neurodegenerative diseases. Various components act by inhibiting cells and proteins of the immune system, which will allow the development of anti-inflammatory and immunosuppressive drugs. This review summarizes the usefulness of the components of snake venoms in the fields of autoimmunity and rheumatology, which can serve as a basis for diverse translational research.
Effect of Aqueous Extract of Achyranthes aspera Leaves on Antiretroviral Drug-Induced Hepatotoxicity in Rats Isaac John Umaru; Mary Athanasius Udoh; Tensaba Andes Akafa; Joseph Oteng; Ingwu Joseph Akem; Ocheifa Mathew Ngbede; Ashaka Fidelis Utioukpan; Aboki Nwunuji Mijinyawa; Ogholo Ogholo Ekup
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5183

Abstract

Achyranthes aspera leaves are believed to reverse drug resistance and increase the efficacy of current drugs. Achyranthes aspera leaves contain many secondary metabolites needed for the redressal of diseases and ailment. Thus, the ART-induced hepatotoxicity in rats. Methodology: Thirty (30) albino rats were divided into 5 groups of 6 each and treated as follows: Group A (no antiretroviral drugs, no extract); group B (antiretroviral drugs alone); group C (extract alone); group D (antiretroviral drug plus 40 mg/kg extract); group E (antiretroviral drug plus 80 mg/kg extract). All treatment lasted for twenty-eight days. Blood samples were collescted and serum ALT and AST determined using UV-spectrophotometer. The mean (± S.E.M) of data were calculated and further analysed for statistical significance using graph Pad Prism 5.0. Results: Mean serum ALT were 36.8 ± 20.24, 56.11 ± 6.12, 54.6 ± 24.18, 90.40 ± 11.14, 88.36 ± 13.10 and that of AST were 143.8 ± 20.24, 208.4 ± 16.13, 60.0 ± 24.18, 164.40 ± 11.14, 52.36 ± 16.14 for groups A, B, C, D, and E respectively. There was a statistically significant difference between the mean values of serum AST for group B and those for group C. However, there was no statistically significant difference between the ALT values for the test and control groups of rats (p value >0.999) Also, there was no statistically significant difference between the mean values of AST for group B and those of groups A, D, E. Conclusions: This extract at a higher concentration should add to the treatment of HIV in synergy with antiviral drugs, However, the extract shown no significant reduction of serum ALT and AST in ART treated rats.
Exploring the Dynamics of Enzyme Activity: Environmental and Biological Influences Muhammad Akram; Urooj Rehman; Misbah Ahmed; Isaac John Umaru
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5268

Abstract

The work presents the classification of enzymes and factors that are affecting enzymatic reactions in the living systems. Factors such as temperature, pH, enzyme concentration, substrate concentration, factors of inhibition, factors of activation, and incubation time are important in influencing enzyme reactions, which are responsible for controlling components in living systems. The majority of enzymes are three-dimensional molecules with complex molecular networks and sensitive to various environmental factors.
Phytochemistry and Pharmacology of Oxystelma Esculentum Abdul Wadood Chishti; Muhammad Akram; Urooj Rehman; Fahad Said Khan; Momina Iftikhar; Isaac John Umaru
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5269

Abstract

Several phytochemicals, including glycosides, alkaloids, flavonoids, and saponins, are present in the widespread medicinal herb Oxystelmaesculentum. These physiologically active substances contribute to the herb's pharmacological properties, which include anti-inflammatory, antioxidant, antibacterial, and antidiabetic effects. Research studies have shown that O. esculentum can be used medicinally to treat a variety of ailments, such as fever, pain, respiratory issues, and digestive issues. It may also have neuroprotective properties and help in blood sugar regulation. Even though its therapeutic qualities appear promising, more research must be done to verify its efficacy, safety, and potential for drug development.
Cutting-Edge Discoveries in Cancer Biology and Therapeutic Development Muhammad Akram; Muhammad Abdullah; Momina Iftikhar; Isaac John Umaru
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5306

Abstract

Growth in precision medicine, immunotherapy, genetics, and new therapeutic approaches is driving the rapid progression of cancer science and drug discovery. Greater tailor-made treatments attacking specific genetic abnormalities and immune systems have become an alternative to the one-size-fits-all approach, bringing renewed hope to patients for improved outcomes and fewer adverse effects. The most critical growth impacting the face of cancer research and drug discovery is summarized in this brief. Next-generation sequencing (NGS) and other methods enable complete genomic profiling, which identifies actionable mutations and guides targeted therapy. Stepping away from blanket chemotherapy, scientists can develop more effective and less toxic drugs by understanding the specific mutations that create each patient's cancer. By blocking the brakes of the immune system, these drugs allow T cells to better fight cancer cells. However, research is ongoing to maximize these treatments' efficacy and safety, particularly in the case of solid tumors. Targeting some of the TME components, such as the extracellular matrix or TME-dwelling immune cells, could provide new treatment strategies. Huge amounts of genetic information are being evaluated, potential medicine candidates are being identified, and patient outcomes are being forecast by AI algorithms. In addition, machine learning algorithms are being employed to improve patient stratification, optimize clinical trial design, and personalize treatment regimens using real-time data. Combination Treatments: Combination therapies employing multiple mechanisms of action are gaining increasing popularity as a result of the flexibility and complexity of cancer. For maximizing efficacy and overcoming resistance, researchers are incorporating immunotherapy with targeted therapy, chemotherapy, radiation therapy, and other modalities. The goal is to keep tumor cells from evading treatment by attacking cancer from a variety of angles. These combinations are currently under investigation in clinical trials, which have had promising results, particularly in cancers such as breast, lung, and melanoma.
Antihyperlipidemic and Haematological Effect of Triherbal Formulation on Triton1339-Induced Hyperlipidemic Rats Isaac John Umaru; Yakubu Ojochenemi Ejeh; Isaac Eleojo Shaibu; Adeyanju Kate Yemisi; Akoh Miracle Talent; Lawal Favour Enyojo
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5325

Abstract

Hyperlipidemia is one of the principal factors underlying the risk for cardiovascular disease. Confirmatory evidence from animal, clinical, and epidemiological studies has clearly established the positive correlation. Allopathic antihyperlipidemic drugs are available but the side effects and contraindications. However, this study was designed to determine the haematological and antihyperlipidemic effect of ethanol leaf ex­tract of triherbal formulation (Mucuna pruriens, Phyllantus amarus, Securidaca longipeduculata) in wistar rat as a cheaper and readily available alternative. 46rats were grouped into normal, diseased, standard drug controls and test groups with seven rats each. quantitative phytochemical, haematological and antihyperlipidemic analysis were carried out according to standard methods. Results revealed presence of saponin, alkaloids, tannin, flavonoids, cardiac glycosides, phenolic with Total phenol exhibiting the highest values haematological results showed improving activities of the formulation on the erythrocytes, heamoglobins, lymphocytes and neutrophiles, this confers good effect on heamatological and immonological parameters especially at higher dose. In antihyperlipidemic activities, triherbal formulation significantly (p≤0.05) decrease the level of TC, TAG, LDL and improve upon HDL in both serum and liver homogenate effects thought to be via inhibition of cholesterol biosynthesis, absorption modification of lypogenic and lipolitic enzymes. Conclusively, the studies indicated triherbal formulation contain bioactive compounds with diverse biological activities such as immunomodulatory, inflammatory, heamatological and lipid profile regulating activities.
The Future of Gene Therapy: Revolutionizing Modern Medicine Muhammad Akram; Alam Afroz Urooj Khan; Isaac John Umaru
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5326

Abstract

The use of gene therapy paired with advanced technology may one day enable chronic illnesses, cancerous diseases, and even genetic defects to be treated via DNA alterations. With developments and promising results in gene CRISPR-Cas9 editing technology, improved treatments and promising results from clinical trials have made gene therapy a possibility. It is also predicted that gene therapy will be used in the future to combat heart issues, cancer, neurological diseases, and other hereditary attributes. Nonetheless, metastatic issues pertaining to ethics, engagement, spending, and the probability of negative consequences over time still remain. In the case of augmented medicine, incorporating stem cells with new artificial intelligence technology will ensure better and more accurate treatment along with greater personalization of gene therapies. This is expected to lead to a whole new realm of precision medicine.
Co-Authors , Jaouher Ben Ali A. J. Amuda Abdul Wadood Chishti Abdullahi Sa’adu Adeseye Abdulmumin Jabir Abid Mahmood Abid Rashid Abimbola Gbenga Olayemi Abimbola Gbenga Olayeni Aboki Nwunuji Mijinyawa Abu Michael Sunday Abubakar Aisami Adeseye Helen Oluwabunmi Adetoyi Moses Gbadebo Adeyanju Kate Yemisi Agbo Chibuike Ekunyi Agbo Christiana Onyindia Ahmad Alhassan Siddan Ajala-Lawal R. A Ajiduku Leyoa Abershi Akafa Andes Tansaba Akafa Andes Tensaba Akoh Miracle Talent Akpan Usenobong Morgan Alam Afroz Urooj Khan Ale Ebenezer Morayo Alice Njolke Mafe Aliyu Olamilekan Najeeb Ameh Godwin Okwori Amna Javed Ananias Amen Anih David Chinonso Anthony Mishara Audu Arowora K. A Arowora K. A. Arowora Kayode Arowora Kayode Adebisi Artu Ishishen John Ashaka Fidelis Utioukpan Atsu Ayi Augustine Absalom Bakari Genevieve Sirina Bando Christopher David Bemhemba Iba Benjamin Nanisi Daniel Bilyaminu Habibu Chabunda Endashi Esseyi Chakfa Nanmar Charles Ayara Chinedu Christian Iheanacho Chukuma Stephen Ezeonu Dafup Kadel Istifanus Dafup Katdel Istifanus Daniel Konka Danjuma Janya Danladi Mbosire Peter Danlami Efoseh David Christopher Bando David Umahi Dawoye Yusufu Debora Akinola Umogbai dulrashid Dauda Maianguwa Ebenezer Morayo Ale Edom Favour Ogochukwu Egbeadumah Maryanne Odufa Egeonu Stephen Ugoeze Eisa Yazeed Ghazwani Eluu Emmanuel Chukwudi Emmanuel Alooma Emmanuel Askeb-nde Joel Emmanuel Askebnde Joel Emmanuel Chikodiri Okoli Emmanuel Efongwa Emmanuel Eluu Chukwudi Emmanuel Olofu Omanchi Emmanuel Omanchi Eric Agim Agaba Etah Hope Mona Evelyn Ovenomo Tony-Enwin Ezeonu C. S Ezugwu Hilary Chikata Fahad Said Khan Favour Joel Bafai Fethi Ahmet Ozdemi Fethi Ahmet Ozdemir Fidelis Okii Ekpo Gabriel Favour Chisom Gaweł Sołowski Genevieve A. Yeboah Genevieve Akpah Yeboah George Okra Hassan Gideon Likida Tiimob Gift Amofa Gloria Omonefe Oladele Gomba Victoria Eno Habiba Idris Adam Haleema Sadia Hauwa A. Umaru Helen Oluwabunmi Hind A. Abdulghafoor Ibrahim Jamilat Mijinyawa Idris Habiba Adams Ikrimah Usman Mohammed Ikwebe Joseph Imo Chinedu Inemesit Samuel Essien Ingwu Joseph Akem Ingwu Joseph Akem3 Iornenge Terungwa Joseph Isaac Eleojo Shaibu Isbah Shahid Iseko Iyoko Kingsly Ismail Yunusa Yuguda Izam Emmanuel David Jackson Soyinka Malantso James Agbu Sunday James Eneji Agwu Jankada Patience Audu Janya Danjuma Jaouher Ben Ali Jehan Mohammad Al-Musawi Jehan Mohammed Al-Musawi Jehan Mohammed Jehan Mohammed Al-Musawi Jibaniya Grace Mchibuma Joanna Afariba Johnson John Odiba Oko Joseph Oteng Josephine Maina Sule Julius Ishaya Salman Kaka Garpiya Yakubu Katchim Evelyn Shadrach Katchin Evelyn Shadrach Kerenhappuch Isaac Umar Kerenhappuch Isaac Umaru Khalid Yahuza Abbas Kingsley Bassey Enang Kingsley Iyoko Iseko Kwabena Owusu Amoah Kyugah Jacob Tersur Lawal Danjuma Tyem Lawal Favour Enyojo Lazaru Joseph Goje Lipana Dorcas Bappa Lubabatu Abdulrasheed Maayam Usman Ahmed Mai-anguwa Abdulrashid Dauda Maianguwa Abdulrashid Dauda Maianguwa Abdulrsashid Dauda Manasseh Ilumunter Matilda Mary Athanasius Udoh Maryam Usman Ahmed Mathew Jacob Mathias Mawuli Ametefe Mgbede Timothy Michael S. Abu Michael Sunday Abu Misbah Ahmed Mohammed Khudhair Hasan Momina Iftikhar Moses Adondua Abah Mosugu O. O Mosugu Ovayoza Omolara Muhammad Abdullah Muhammad Akram Muhammad Bashir Muhammad Muhammad Haris Baig Muhammad Tayyab Aslam Muhammad Zuhairah Ismail Musa Azegya Mustapha Musbau Adekunle Yahaya Nanyak Zingfa Galam Nasiru Audu Ngabea Nkechi Gift Ijeomah Nkiri Annasthesia Ekubnse Nosheen Aslam Nurudeen Umar Abdulkadir Nwachukwu Favour Onyinyechi Nwofor Innocent Obadiah Saveni Yusuf Oche Williams Ujah Ocheifa Mathew Ngbede Ocheifa Matthew Ngbede Odok Endurance Akam Ogar Fonne Okang Ogholo Ogholo Ekup Ojochenemi E. Yakubu Ojochenemi Ejeh Yakubu Okoli Emmanuel Okpanachi Nuhu Oyibo Okrah George Hassan Olabanji Martina Morolake Olawale Otitoju Oluwasegun M. Oladimeji Omachi Blessing John Onwubiko A. Henry Onwubiko N. Grace Otashu Kenneth Frank Otitoju Olawale Otitoju Oluwale Otitujo Olawale Ozzioma Praise Acha Panah Philemon Peter Ise Uduak Precious Chioma Jack Prince Kwadwo Gyasi Prince Osei Akumia Prosper Uneju Peter Queen Uyo Williams Rashida Ismail Mohammed Sabahat Abbas Samuel Tamunoiyowuna Cockeye Brown Selumun Solomon Ipav Shadrach Philip Shelter Agbeko Bobie Shitta Nasisi Namuma Simon Teza Zinas Solomon Chuanu Solomon Godiya Marvelous Solomon O. Asare Solomon Ossom Asare Steve Osagie Asuelimen Sukyakma Manu Sulaiman Abubakar Aliyu Sule John Ugbedeojo Tahmina Maqbool Tensaba Andes Akafa Tongle Nanle John Tsokwa Punarimam Rebecca Tyem Lawal Danjuma Ubur Terzulum Wilson Ugwuala Chimaobi Melvin Ugwuoke Kenneth C Umme Laila Urooj Rehman Usenobong Morgan Akpan Usman Ikira Usman Lukman Adamu Victor Duniya Sheneni Victor Makanjuola Victoria Ifeoluwa Ayo Vika Tensaba Akafa Williams Oche Ujah Wisdom L. Benjamin Yakubu Ojochenemi Ejeh Zainab Bello Dambazau Zephaniah Hananiah Shenia