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All Journal Jurnal Sains dan Teknologi MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation
Roy Indrianto Bangar
Universitas Prima Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Dentistry Electrical & Electronics Engineering Energy Engineering Health Professions Industrial & Manufacturing Engineering Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary

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Formulasi dan Evaluasi Sediaan Sabun Cair dari Umbi Porang (Amorphophallus muelleri Blume): Novia Agustini Irmasyari Siregar; Roy Indrianto Bangar; Erida Novriani
INSOLOGI: Jurnal Sains dan Teknologi Vol. 5 No. 1 (2026): Februari 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v5i1.7530

Abstract

Porang tuber (Amorphophallus muelleri Blume) is a potential natural resource that can be developed as an active ingredient in cosmetic preparations, particularly liquid soap. This study aimed to formulate and evaluate liquid soap containing porang tuber extract and to determine its physical quality characteristics. The tubers were extracted by maceration using 70% ethanol. Prior to extraction, simplicia characterization was performed, including determination of moisture content, water-soluble extractive, ethanol-soluble extractive, total ash, and acid-insoluble ash. Phytochemical screening was carried out to identify secondary metabolites. The extract was formulated into liquid soap preparations with concentrations of 3%, 5%, and 8%. The evaluation included organoleptic tests, pH measurement, foam height test, irritation test, and hedonic test. The results of simplicia characterization showed that all parameters met the requirements of the Herbal Pharmacopeia. Phytochemical screening indicated the presence of alkaloids, flavonoids, saponins, tannins, and triterpenoids. The formulated liquid soaps showed acceptable physical characteristics, pH values within the Indonesian National Standard range (8–11), adequate foam formation, and no skin irritation. Hedonic testing demonstrated that all formulations were acceptable to panelists. It can be concluded that porang tuber extract has potential as a natural active ingredient in liquid soap formulations.
Formulasi dan Evaluasi Sediaan Roll on Aromaterapi Minyak Atsiri Buah Andaliman (Zanthoxylum Acanthopodium Dc.) Novelia Zwi Dwinayanti Silaban; Roy Indrianto Bangar; Asyrun Alkhairi Lubis
INSOLOGI: Jurnal Sains dan Teknologi Vol. 5 No. 1 (2026): Februari 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v5i1.7535

Abstract

Andaliman (Zanthoxylum acanthopodium DC.) is an endemic spice from North Sumatra with significant therapeutic potential derived from its essential oils. Terpenoid compounds such as geranyl acetate, limonene, and citronellol in andaliman are recognized for their efficacy in aromatherapy to alleviate nausea and vomiting. This study aims to construct an aromatherapy roll-on formulation using andaliman fruit essential oil and to evaluate its physical characteristics and safety profile. The research employed a laboratory experimental method, utilizing the Stahl steam distillation technique for essential oil isolation. The preparations were formulated into three concentration variations: F0 (0%), F1 (5%), and F2 (10%). Evaluation parameters included organoleptic properties, homogeneity, viscosity, pH value, dermal irritation tests, and hedonic (preference) tests. The results demonstrated that all formulas maintained excellent physical stability and homogeneity. The pH values ranged from 5.52 to 6.06, which is considered safe as it aligns with the physiological pH of human skin (4.5–6.5). Irritation tests confirmed that the formulations did not trigger adverse skin reactions in respondents. According to the hedonic test, panelists showed high preference for aroma, texture, and comfort, although the scent longevity requires further optimization due to the volatile nature of the essential oil. Overall, the andaliman essential oil aromatherapy roll-on meets the physical quality and safety standards for topical preparations.
Perbandingan Ektrak Konvensional dengan Green Ektraksi Umbi Porang (Amorphophallus Muelleri) terhadap Aktivitas Antioksidan Pasti Marito Samosir; Roy Indrianto Bangar; Vera Estefania Kaban
INSOLOGI: Jurnal Sains dan Teknologi Vol. 5 No. 1 (2026): Februari 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v5i1.7536

Abstract

Porang tuber (Amorphophallus muelleri) contains various bioactive compounds with potential antioxidant activity, while extraction efficiency is strongly influenced by the applied method. This study aimed to compare conventional and environmentally friendly extraction techniques, including maceration, Soxhlet extraction, Microwave-Assisted Extraction (MAE), and Ultrasonic-Assisted Extraction (UAE), using 70% ethanol as the solvent. Antioxidant activity was evaluated using the DPPH radical scavenging assay and expressed as IC₅₀ values. The results showed that differences in extraction methods significantly affected antioxidant activity. Soxhlet extraction exhibited the highest antioxidant activity with the lowest IC₅₀ value (0.1788 µg/mL), followed by MAE (0.4312 µg/mL), maceration (0.6315 µg/mL), and UAE (0.6574 µg/mL). The superiority of the Soxhlet method is related to continuous solvent reflux and heat-assisted mass transfer, which enhance the release of antioxidant compounds. These findings confirm that porang tuber is a promising natural antioxidant source, with Soxhlet extraction identified as the most effective method under the applied experimental conditions for future development of functional food, nutraceutical, and pharmaceutical applications.
Kajian Potensi Etil Asetat Ekstrak Daun Andaliman : Total Fenol Flavonoid dan Aktivitas Uji Antioksidan Muhtamilatur Rahma; Roy Indrianto Bangar; Muhammad Yunus
INSOLOGI: Jurnal Sains dan Teknologi Vol. 5 No. 1 (2026): Februari 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v5i1.7537

Abstract

Andaliman leaves (Zanthoxylum acanthopodium DC.) are a traditional plant native to North Sumatra with potential as a natural antioxidant source due to their phenolic and flavonoid compounds. This study aimed to evaluate the antioxidant potential of the ethyl acetate extract of andaliman leaves based on total phenolic content, total flavonoid content, and antioxidant activity. Extraction was carried out using the maceration method with ethyl acetate as the solvent. Total flavonoid content was determined using the AlCl₃ method with quercetin as the standard, while total phenolic content was analyzed using the Folin– Ciocalteu method with gallic acid as the standard. Antioxidant activity was evaluated using the DPPH radical scavenging assay. The results showed that the ethyl acetate extract of andaliman leaves contained 73.40 mg QE/g extract of total flavonoids (7.3%) and 148.48 mg GAE/g extract of total phenolics. The antioxidant activity test yielded an IC₅₀ value of 4,2485 µg/mL, indicating that the extract exhibits very strong antioxidant activity. The high levels of phenolic and flavonoid compounds are believed to play an important role in the radical scavenging activity observed. Based on these findings, it can be concluded that the ethyl acetate extract of andaliman leaves has strong potential to be developed as a natural antioxidant source for applications in the pharmaceutical and health fields.
ANTIOXIDANT CREAM FORMULATION OF PORANG TUBER ETHANOL EXTRACT AS AN ANTI-AGING AGENT Ain Naia; Roy Indrianto Bangar; Hariyadi Dharmawan Syahputra
MEDALION Journal: Medical Research, Nursing, Health and Midwife Participation Vol. 7 No. 2 (2026): June
Publisher : PT. Radja Intercontinental Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59733/medalion.v7i2.292

Abstract

Irreversible skin aging begins in early adulthood due to intrinsic factors such as genetics and cellular metabolism and extrinsic factors such as ultraviolet exposure, smoking, pollution, and lifestyle, which trigger reactive oxygen species (ROS) and collagen damage, leading to wrinkles and reduced skin elasticity. This study aimed to formulate an optimal anti-aging cream from ethanol extract of porang tubers (Amorphophallus muelleri Blume) using variations in the HLB value of Span 60-Tween 80 emulsifiers. This quantitative experimental study used three cream formulas (F1: HLB 4.95; F2: HLB 5.7; F3: HLB 6.8) prepared from 3 kg of porang tubers obtained from Sirapit, Langkat. Evaluations included organoleptic properties, homogeneity, pH, viscosity, spreadability, adhesiveness, cycling-test stability, irritation, preference, and antioxidant activity using the DPPH method. The results showed that F2 was the optimal formula, with medium viscosity, spreadability of 6.2 cm², pH 5.8, stability for six cycles, and an IC₅₀ value of approximately 114 μg/mL, indicating moderate antioxidant activity. Formula F2 therefore has potential as a topical antioxidant preparation for preventing premature skin aging based on locally sourced tropical material.
Analisis Kandungan Total Lemak pada Food Replacement (X) dan Fermentasi Akar Teratai (Nelumbo nucifera) Cut Rahil Sofia; Roy Indrianto Bangar; Erida Novriani
INSOLOGI: Jurnal Sains dan Teknologi Vol. 5 No. 2 (2026): April 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v5i2.7794

Abstract

This research relies on the analysis of fat content from the food replacement product (x) and lotus root (nelumbo nucifera) fermentation by utilizing the Soxhlet method. The experiment was conducted by extraction using n-hexane solvent for six hours. The fat content was determined based on the difference in weight after extraction. The findings showed that the fat content in the food replacement product (x) reached 63.60%, while in the lotus root fermentation it was 89.19%. These high numbers are influenced by the composition of the ingredients used, the effectiveness of nonpolar solvents, as well as changes in the matrix structure due to fermentation which increases lipid accessibility. The fermentation process, which lasted for 22 days, enhances enzymatic effectiveness that damages cell walls, thereby facilitating the extraction of lipophilic compounds. The results of this study indicate that fermentation can increase the measurement of fat in plant-based food materials, but the figures obtained reflect the fat that was successfully extracted, not pure fat. According to regulations in Indonesia, there is not yet a maximum limit for fat content in foods for special nutritional needs.
Co-Authors Ain Naia Asyrun Alkhairi Lubis Cut Rahil Sofia Erida Novriani Hariyadi Dharmawan Syahputra Muhammad Yunus Muhtamilatur Rahma Novelia Zwi Dwinayanti Silaban Novia Agustini Irmasyari Siregar Pasti Marito Samosir Vera Estefania Kaban