Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Universa Medicina Journal SAGO Gizi dan Kesehatan
Sumartini, Ni Ketut
Unknown Affiliation
Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Effect of astaxanthin supplementation on oxidative stress in adult women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials Pratiwi, Donna; Harimawan, Agustinus I Wayan; Weta, I Wayan; Sumartini, Ni Ketut; Awan, Syuma Adhy; Sutadarma, I Wayan Gede
Universa Medicina Vol. 45 No. 1 (2026)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2026.v45.125-134

Abstract

BackgroundPolycystic ovary syndrome (PCOS) can cause significant morbidity through fertility disorders and most often found in the productive age. Recent research suggests that oxidative stress plays an important role in the pathogenesis of PCOS. Astaxanthin (AST) has broad protective effects, particularly in the regulation of antioxidant and anti-inflammatory activity. The objective of this systematic review and meta-analysis was to evaluate the efficacy of AST supplementation on PCOS management. MethodsA systematic literature search was conducted in PubMed, Scopus, Science Direct, and Cochrane Library from January 2020 to March 2025. Randomized controlled trials (RCTs) assessing astaxanthin supplementation in adult women with PCOS were included. Outcomes of interest were malondialdehyde (MDA), superoxide dismutase (SOD), and total antioxidant capacity (TAC). Data were analyzed using Review Manager (RevMan) version 5.4.1. Pooled effects were calculated as mean differences (MDs) with 95% confidence intervals (CIs).  ResultsFour RCTs involving 194 participants were included. Astaxanthin supplementation significantly reduced MDA levels (MD −0.670; 95% CI −1.070 to −0.270; p = 0.001; I² = 93%) and significantly increased TAC levels (MD 0.030; 95% CI 0.000 to 0.060; p = 0.030; I² = 76%). No significant effect was observed on SOD levels (MD 0.025; 95% CI −0.850 to 1.350; p = 0.660; I² = 57%). The overall risk of bias across included studies was low. ConclusionThis systematic review shows that AST supplementation significantly reduced lipid peroxidation in women with PCOS. These findings suggest that AST may serve as potential adjuvant antioxidant therapy in PCOS management.
The effect of carbohydrate loading on physical performance and adaptations in amateur sports enthusiasts: A systematic review Dewvi, Putu Ayu Savitri; Wulandari, Putu Ayu; Devi, Natasha Pradnya; Sumartini, Ni Ketut
Jurnal SAGO Gizi dan Kesehatan Vol 7, No 1 (2026): April
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v7i1.3080

Abstract

Background: Carbohydrate loading (CL) increases muscle glycogen reserves before intense physical activity. While CL has been shown to be beneficial for elite athletes, the metabolic capacity and activity duration of amateur and recreational athletes are variable. As sports nutrition guidelines for amateur athletes vary, especially regarding CL indications, duration, and dose, this variance has practical and therapeutic ramifications.Objectives: This study aimed to systematically review the effects of carbohydrate loading on the physical performance and adaptation of amateur sports enthusiasts.Methods: This systematic review was conducted following the PRISMA 2020 guidelines. We searched PubMed, ScienceDirect, ProQuest, and Google Scholar for publications from 2005 to 2025. Experimental or randomized controlled trials of high-carbohydrate diets in non-elite athletes were included in this review. Two reviewers independently selected the articles, and a third reviewer resolved any disagreements. VO2max, time to exhaustion, race results, and metabolic responses were all recorded. The risk of bias and study quality were assessed using the Cochrane Risk of Bias 2.0 and the NIH Quality Assessment Tools.Results: Seven studies were included in the analysis. Five trials found that carbohydrate loading improved endurance and glucose stability and reduced fatigue. Events lasting > 90 min showed the greatest performance gains. Short-term and moderate-intensity activities had no meaningful impact on the two studies. These differences may have been caused by differences in training, glycogen storage, and diet.Conclusion: Carbohydrate loading improves endurance performance and metabolic efficiency, particularly during long-duration exercise. However, inter-individual heterogeneity emphasizes the need for tailored carbohydrate regimens to maximize athletic performance in endurance sports.
Co-Authors Awan, Syuma Adhy Devi, Natasha Pradnya Dewvi, Putu Ayu Savitri Harimawan, Agustinus I Wayan I Wayan Gede Sutadarma I Wayan Weta Pratiwi, Donna Wulandari, Putu Ayu